Search Results - "Skvortsov, D A"

Assays for detection of telomerase activity by Skvortsov, D A, Zvereva, M E, Shpanchenko, O V, Dontsova, O A

“…Progressive loss of the telomeric ends of chromosomes caused by the semi-conservative mechanism of DNA replication is an important timing mechanism which…”
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Cooperation and Competition of RNA Secondary Structure and RNA-Protein Interactions in the Regulation of Alternative Splicing by Vorobeva, M A, Skvortsov, D A, Pervouchine, D D

“…The regulation of alternative splicing in eukaryotic cells is carried out through the coordinated action of a large number of factors, including RNA-binding…”
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Replication protein A modulates the activity of human telomerase in vitro by Rubtsova, M. P, Skvortsov, D. A, Petruseva, I. O, Lavrik, O. I, Spirin, P. V, Prasolov, V. S, Kisseljov, F. L, Dontsova, O. A

“…Our aim was to investigate how replication protein A (RPA) in a wide range of concentration can regulate the activity of human telomerase. We used an in vitro…”
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Nuclear Scanning Microprobe Analysis of Silicon Carbide Epilayers by Buzoverya, M. E., Karpov, I. A., Arkhipov, A. Yu, Skvortsov, D. A., Neverov, V. A., Mamin, B. F.

“…The surfaces of homoepitaxial 4H-SiC layers were studied using a nuclear scanning microprobe in the Rutherford backscattering mode. Analysis of the state of…”
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New C(4)-esters of podophyllotoxin and epipodophyllotoxin with heterocyclic moieties by Elisseev, I. A., Nurieva, E. V., Zefirov, N. A., Kolchanova, A. Yu, Skvortsov, D. A., Milaeva, E. R., Zefirova, O. N.

“…Esters of podophyllotoxin and epipodophyllotoxin with 4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)butanoic and (4 R )- N -( tert…”
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Screening of a series of 3,5-disubstituted 1,2,4-thiadiazoles for selectivity of cytotoxic action to cancer cells by Proshin, A. N., Trofimova, T. P., Zefirova, O. N., Zhirkina, I. V., Skvortsov, D. A., Bachurin, S. O.

“…New 3,5-disubstituted-1,2,4-thiadiazoles were synthesized and together with a series of their analogs obtained earlier were tested for cytotoxic activity to…”
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Synthesis of 8-carboxamide-substituted angelicin derivatives by Klyatskina, S. R., Olshanova, A. S., Dagaev, N. D., Vorozhtsov, N. I., Skvortsov, D. A., Vasilenko, D. A., Averina, E. B., Zyk, N. V., Beloglazkina, E. K.

“…A method for the synthesis of 4-methyl-2-oxo-9-phenyl-2 H -furo[2,3- h ]chromene-8-carboxylic acid amides combining in the structure the angelicin core with…”
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Terpyridine-Containing 5-(2-Pyridylmethylene)-2-thioimidazolones and Their Coordination Compounds with Copper(II) Chloride: Synthesis and Cytotoxicity by Salimova, I. O., Berezina, A. V., Moiseeva, A. A., Skvortsov, D. A., Sukonnikov, M. A., Zyk, N. V., Beloglazkina, E. K.

“…Methods for the synthesis of new ditopic organic ligands containing coordinating fragments of two types, terpyridine and thiohydantoin, have been developed…”
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Synthesis of dispirooxindoles containing N-unsubstituted heterocyclic moieties and study of their anticancer activity by Beloglazkina, A. A., Karpov, N. A., Mefedova, S. R., Polyakov, V. S., Skvortsov, D. A., Kalinina, M. A., Tafeenko, V. A., Majouga, A. G., Zyk, N. V., Beloglazkina, E. K.

“…A convenient method is proposed for the synthesis of N -unsubstituted spiroxindoles with different heterocyclic moieties (2-thiohydantoin, hydantoin, and…”
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From Toxicity to Selectivity: Coculture of the Fluorescent Tumor and Non-Tumor Lung Cells and High-Throughput Screening of Anticancer Compounds by Skvortsov, D.A., Kalinina, M.A., Zhirkina, I.V., Vasilyeva, L.A., Ivanenkov, Y.A., Sergiev, P.V., Dontsova, O.A.

“…For the search of anticancer compounds in modern large chemical libraries, new approaches are of great importance. Cocultivation of the cells of tumor and…”
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Specific course of COVID-19 associated pneumonia in the tuberculosis patient after pleuropneumonectomy by Zhukova, E. M., Laushkina, Zh. A., Skvortsov, D. A., Stavitskaya, N. V.

“…The article describes a clinical case of viral pneumonia associated with COVID-19 of the only lung, it developed in the patient 30 days after…”
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Novel 5-N,N-disubstituted-5-amino-3-(2-oxopropyl)-1,2,4-thiadiazoles: synthesis and study of neuroprotective and antiproliferative properties by Proshin, A. N., Trofimova, T. P., Zefirova, O. N., Petrova, L. N., Skvortsov, D. A., Bachurin, S. O.

“…A series of eight novel 5- N , N -disubstituted-5-amino-3-(2-oxopropyl)-1,2,4-thiadiazoles with diverse lipophilic groups was obtained by reaction of…”
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Imidazole Derivative As a Novel Translation Inhibitor by Lukianov, D A, Buev, V S, Ivanenkov, Y A, Kartsev, V G, Skvortsov, D A, Osterman, I A, Sergiev, P V

“…Searching for novel compounds with antibiotic activity and understanding their mechanism of action is extremely important. The ribosome is one of the main…”
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Synthesis of 4,4′-substituted 2,2′-[ethane-1,2-diylbis(selanediyl)]bis(1H-imidazol-5(4H)-ones) by Finko, A. V., Sokolov, A. I., Vasilyeva, L. A., Skvortsov, D. A., Al-Khazraji, A. S. H., Ofitserov, E. N., Zyk, N. V., Majouga, A. G., Beloglazkina, E. K.

“…Synthesis of new bis(seleno-imidazolone) derivatives bearing the alkyl and aryl moieties at the N(1) atom of the five-membered ring was developed. Cytotoxicity…”
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High expression levels and nuclear localization of novel Danio rerio ncRNA transcribed from a genomic region containing repetitive elements by Shubernetskaya, O. S., Skvortsov, D. A., Evfratov, S. A., Rubtsova, M. P., Belova, E. V., Strelkova, O. S., Cherepaninets, V. D., Zhironkina, O. A., Olovnikov, A. M., Zvereva, M. E., Kireev, I. I., Dontsova, O. A.

“…Noncoding and repetitive sequences make up a large part of the genome of high eukaryotes, but the elucidation of their roles and mechanisms of action are…”
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New ASGPR-targeted ligands based on glycoconjugated natural triterpenoids by Yamansarov, E. Yu, Skvortsov, D. A., Lopukhov, A. V., Kovalev, S. V., Evteev, S. A., Petrov, R. A., Klyachko, N. L., Zyk, N. V., Beloglazkina, E. K., Ivanenkov, Ya. A., Majouga, A. G.

“…New ligands for targeted delivery to the liver based on glycoconjugated natural triterpenoids are proposed. Simple chemical transformations of starting lupane…”
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Synthesis of a new betulinic acid glycoconjugate with N-acetyl-d-galactosamine for the targeted delivery to hepatocellular carcinoma cells by Olshanova, A. S., Yamansarov, E. Yu, Seleznev, E. I., Kovalev, S. V., Lopuhov, A. V., Skvortsov, D. A., Evteev, S. A., Klyachko, N. L., Beloglazkina, E. K., Ivanenkov, Ya. A., Majouga, A. G.

“…A new promising conjugate of betulinic acid with N -acetyl- d -galactosamine was synthesized by the simple reaction sequence: esterification and…”
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Comparative Analysis of Long Noncoding RNA Expression in Human Hepatocyte Cell Lines and Liver by Burenina, O. Y., Zatsepin, T. S., Kim, E. F., Metelin, A. V., Skvortsov, D. A., Rubtsova, M. P., Dontsova, O. A.

“…Long noncoding RNAs (lncRNAs) are promising biomarkers and potential targets for liver cancer therapy. Stable hepatocyte lines are used in vitro to investigate…”
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Recombinogenic Telomeres in Diploid Sorex granarius (Soricidae, Eulipotyphla) Fibroblast Cells by Zhdanova, N. S., Draskovic, I., Minina, J. M., Karamysheva, T. V., Novo, C. L., Liu, W.-Y., Porreca, R. M., Gibaud, A., Zvereva, M. E., Skvortsov, D. A., Rubtsov, N. B., Londoño-Vallejo, A.

“…The telomere structure in the Iberian shrew Sorex granarius is characterized by unique, striking features, with short arms of acrocentric chromosomes carrying…”
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Nuclear Non-Proliferation Security on Exportation of Fast Reactors with a Closed Fuel Cycle by Gorin, N. V., Voloshin, N. P., Churikov, Yu. I., Chebeskov, A. N., Kuchinov, V. P., Vasiliev, A. P., Moiseev, A. V., Shepelev, S. F., Skvortsov, D. A., Zhurin, S. I., Shidlovskiy, V. V., Krivtsov, A. V.

“…The exportation of fast reactors with a closed nuclear fuel cycle to countries that do not have nuclear weapons could commence within the next few decades,…”
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