Search Results - "Skuland, Tonje"

Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model by Skuland, Tonje, Låg, Marit, Gutleb, Arno C, Brinchmann, Bendik C, Serchi, Tommaso, Øvrevik, Johan, Holme, Jørn A, Refsnes, Magne

“…Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health effects of SiNPs have therefore…”
Get full text

Characterization of elements, PAHs, AhR-activity and pro-inflammatory responses of road tunnel-derived particulate matter in human hepatocyte-like and bronchial epithelial cells by Holme, Jørn A., Låg, Marit, Skuland, Tonje, Parenicová, Martina, Ciganek, Miroslav, Penciková, Katerina, Grytting, Vegard Sæter, Neca, Jiri, Øvrevik, Johan, Mariussen, Espen, Jørgensen, Rikke Bramming, Refsnes, Magne, Machala, Miroslav

“…The aims were to characterize the content of elements and polycyclic aromatic hydrocarbons (PAHs) in size-separated particulate matter (PM) sampled in a road…”
Get full text

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s) by Brinchmann, Bendik C, Skuland, Tonje, Rambøl, Mia H, Szoke, Krisztina, Brinchmann, Jan E, Gutleb, Arno C, Moschini, Elisa, Kubátová, Alena, Kukowski, Klara, Le Ferrec, Eric, Lagadic-Gossmann, Dominique, Schwarze, Per E, Låg, Marit, Refsnes, Magne, Øvrevik, Johan, Holme, Jørn A

“…Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD),…”
Get full text

Respirable stone particles differ in their ability to induce cytotoxicity and pro-inflammatory responses in cell models of the human airways by Grytting, Vegard Sæter, Refsnes, Magne, Øvrevik, Johan, Halle, Marit Sigrid, Schönenberger, Jasmin, van der Lelij, Roelant, Snilsberg, Brynhild, Skuland, Tonje, Blom, Richard, Låg, Marit

“…Respirable stone- and mineral particles may be a major constituent in occupational and ambient air pollution and represent a possible health hazard. However,…”
Get full text

Role of different mechanisms in pro-inflammatory responses triggered by traffic-derived particulate matter in human bronchiolar epithelial cells by Refsnes, Magne, Skuland, Tonje, Jørgensen, Rikke, Sæter-Grytting, Vegard, Snilsberg, Brynhild, Øvrevik, Johan, Holme, Jørn A, Låg, Marit

“…Traffic-derived particles are important contributors to the adverse health effects of ambient particulate matter (PM). In Nordic countries, mineral particles…”
Get full text

Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages by Sandberg, Wiggo J, Låg, Marit, Holme, Jørn A, Friede, Bernd, Gualtieri, Maurizio, Kruszewski, Marcin, Schwarze, Per E, Skuland, Tonje, Refsnes, Magne

“…Respirable crystalline silica (silicon dioxide; SiO₂, quartz) particles are known to induce chronic inflammation and lung disease upon long-term inhalation,…”
Get full text

Proinflammatory effects of diesel exhaust particles from moderate blend concentrations of 1st and 2nd generation biodiesel in BEAS-2B bronchial epithelial cells − The FuelHealth project by Skuland, Tonje S, Refsnes, Magne, Magnusson, Pål, Oczkowski, Michał, Gromadzka-Ostrowska, Joanna, Kruszewski, Marcin, Mruk, Remigiusz, Myhre, Oddvar, Lankoff, Anna, Øvrevik, Johan

“…Abstract Biodiesel fuel fuels are introduced at an increasing extent as a more carbon-neutral alternative to reduce CO2 -emissions, compared to conventional…”
Get full text

Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells by Skuland, Tonje, Grytting, Vegard Saeter, Låg, Marit, Jargensen, Rikke Braemming, Snilsberg, Brynhild, Leseman, Daan L. A. C, Kubátová, Alena, Emond, Jessica, Cassee, Flemming R, Holme, Jarn A, Øvrevik, Johan, Refsnes, Magne

“…Abstract Background Traffic particulate matter (PM) comprises a mixture of particles from fuel combustion and wear of road pavement, tires and brakes. In…”
Get full text

Importance of agglomeration state and exposure conditions for uptake and pro-inflammatory responses to amorphous silica nanoparticles in bronchial epithelial cells by Gualtieri, Maurizio, Skuland, Tonje, Iversen, Tore-Geir, Låg, Marit, Schwarze, Per, Bilani ová, Dagmar, Pojana, Giulio, Refsnes, Magne

“…Abstract Amorphous silica nanoparticles (SiNPs, 30 and 50 nm) and rhodamine-coated SiNPs (50 nm) were examined for their ability to induce pro-inflammatory…”
Get full text

Role of scavenger receptors in silica nanoparticle-induced cytokine responses in bronchial epithelial cells by Refsnes, Magne, Skuland, Tonje, Øvrevik, Johan, Låg, Marit

“…•Silica nanoparticles (SiNP) induce IL-6, CXCL8, IL-1α and IL-1β and TGF-α responses in epithelial lung cells.•The scavenger-receptors SR-B1, LOX-1 and CXCL16…”
Get full text

Concentration‐dependent cytokine responses of silica nanoparticles and role of ROS in human lung epithelial cells by Refsnes, Magne, Skuland, Tonje, Lilleaas, Edel, Øvrevik, Johan, Låg, Marit

“…Reactive oxygen species (ROS) is regarded as a critical denominator in nanoparticle toxicology and inflammation. Previously, we have shown that silica…”
Get full text

The effects of fine particulate matter (SRM 2786) on three different 3D lung models exposed at the air-liquid interface – A comparative study by Grytting, Vegard Sæter, Skuland, Tonje, Ballangby, Jarle, Refsnes, Magne, Låg, Marit, Øvrevik, Johan, Mariussen, Espen

“…3D cell culture models exposed at the air-liquid interface (ALI) represent a potential alternative to animal experiments for hazard and risk assessment of…”
Get full text

Silica nanoparticles induce cytokine responses in lung epithelial cells through activation of a p38/TACE/TGF-α/EGFR-pathway and NF-κB signalling by SKULAND, Tonje, ØVREVIK, Johan, LAG, Marit, SCHWARZE, Per, REFSNES, Magne

Get full text

Silica nanoparticles induce cytokine responses in lung epithelial cells through activation of a p38/TACE/TGF-α/EGFR-pathway and NF-κΒ signalling by Skuland, Tonje, Øvrevik, Johan, Låg, Marit, Schwarze, Per, Refsnes, Magne

“…Amorphous silica nanoparticles (SiNPs) have previously been shown to induce marked cytokine (interleukin-6; IL-6 and interleukin-8; CXCL8/IL-8) responses…”
Get full text

Biological effects of combustion-derived particles from different biomass sources on human bronchial epithelial cells by Marchetti, Sara, Mollerup, Steen, Gutzkow, Kristine Bjerve, Rizzi, Cristiana, Skuland, Tonje, Refsnes, Magne, Colombo, Anita, Øvrevik, Johan, Mantecca, Paride, Holme, Jørn Andreas

“…Combustion-derived particles (CDPs), in particular from traffic, are regarded as a central contributor for adverse health effects linked to air pollution…”
Get full text

Silica Nanoparticle‐induced Cytokine Responses in BEAS‐2B and HBEC3‐KT Cells: Significance of Particle Size and Signalling Pathways in Different Lung Cell Cultures by Låg, Marit, Skuland, Tonje, Godymchuk, Anna, Nguyen, Thu H. T., Pham, Hang L. T., Refsnes, Magne

“…We have previously reported that silica nanoparticles (SiNPs) of nominal size 50 nm (Si50) induce the pro‐inflammatory cytokines CXCL8 and IL‐6 in BEAS‐2B…”
Get full text

85 An Approach to Test Effects on Secondary Organs via Lung Cells Exposed at the Air Liquid Interphase by Mariussen, Espen, Skuland, Tonje, Dahlman, Hans Jørgen, Låg, Marit, Øvrevik, Johan

“…Abstract Air pollutions are shown to increase the occurrence of cardiovascular diseases and ischemic stroke. These effects imply an indirect exposure of…”
Get full text

76 Combined Exposure to road wear Particles and Diesel Exhaust Particles Induces Enhanced pro-Inflammatory Responses in Cells of the Human Airways by ter Grytting, Vegard Sæ, Kirkerød, Elisabeth, Skuland, Tonje, Refsnes, Magne, Øvrevik, Johan, Gustafsson, Mats, Låg, Marit

“…Abstract Ambient particulate matter (PM) is one of the leading environmental mortality risk factors worldwide. PM is not a single entity but consists of a…”
Get full text

Combined Exposure to road wear Particles and Diesel Exhaust Particles Induces Enhanced pro-Inflammatory Responses in Cells of the Human Airways by Sæter Grytting, Vegard, Kirkerød, Elisabeth, Skuland, Tonje, Refsnes, Magne, Øvrevik, Johan, Gustafsson, Mats, Låg, Marit

“…Ambient particulate matter (PM) is one of the leading environmental mortality risk factors worldwide. PM is not a single entity but consists of a complex and…”
Get full text

Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells by Brinchmann, Bendik C., Holme, Jørn A., Frerker, Nadine, Rambøl, Mia H., Karlsen, Tommy, Brinchmann, Jan E., Kubátová, Alena, Kukowski, Klara, Skuland, Tonje, Øvrevik, Johan

“…Exposure to fine particulate matter (PM2.5) from incomplete fossil fuel combustion (coal, oil, gas and diesel) has been linked to increased morbidity and…”
Get full text