Search Results - "Skryma, R."

TRPV6 channel controls prostate cancer cell proliferation via Ca2+/NFAT-dependent pathways by LEHEN'KYI, V, FLOURAKIS, M, SKRYMAL, R, PREVARSKAYA, N

“…The transient receptor potential channel, subfamily V, member 6 (TRPV6), is strongly expressed in advanced prostate cancer and significantly correlates with…”
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TRPV6 channel controls prostate cancer cell proliferation via Ca(2+)/NFAT-dependent pathways by Lehen'kyi, V, Flourakis, M, Skryma, R, Prevarskaya, N

“…The transient receptor potential channel, subfamily V, member 6 (TRPV6), is strongly expressed in advanced prostate cancer and significantly correlates with…”
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Intermediate-conductance Ca2+-activated K+ channels (IKCa1) regulate human prostate cancer cell proliferation through a close control of calcium entry by Lallet-Daher, H, Roudbaraki, M, Bavencoffe, A, Mariot, P, Gackière, F, Bidaux, G, Urbain, R, Gosset, P, Delcourt, P, Fleurisse, L, Slomianny, C, Dewailly, E, Mauroy, B, Bonnal, J L, Skryma, R, Prevarskaya, N

“…Accumulating data point to K + channels as relevant players in controlling cell cycle progression and proliferation of human cancer cells, including prostate…”
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Ion channels in death and differentiation of prostate cancer cells by Prevarskaya, N, Skryma, R, Bidaux, G, Flourakis, M, Shuba, Y

“…Plasma membrane ion channels contribute to virtually all basic cellular processes, including such crucial ones for maintaining tissue homeostasis as…”
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Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells by Flourakis, M, Lehen'kyi, V, Beck, B, Raphaël, M, Vandenberghe, M, Abeele, F V, Roudbaraki, M, Lepage, G, Mauroy, B, Romanin, C, Shuba, Y, Skryma, R, Prevarskaya, N

“…The molecular nature of calcium (Ca 2+ )-dependent mechanisms and the ion channels having a major role in the apoptosis of cancer cells remain a subject of…”
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Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death by Kondratskyi, A, Yassine, M, Slomianny, C, Kondratska, K, Gordienko, D, Dewailly, E, Lehen'kyi, V, Skryma, R, Prevarskaya, N

“…The growing number of studies suggested that inhibition of autophagy enhances the efficacy of Akt kinase inhibitors in cancer therapy. Here, we provide…”
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Calcium signalling and cancer cell growth by Capiod, T, Shuba, Y, Skryma, R, Prevarskaya, N

“…Cancer is caused by defects in the mechanisms underlying cell proliferation and cell death. Calcium ions are central to both phenomena, serving as major…”
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Acceleration of keratinocyte differentiation by transient receptor potential vanilloid (TRPV6) channel activation by Lehen'kyi, V, Vandenberghe, M, Belaubre, F, Julié, S, Castex-Rizzi, N, Skryma, R, Prevarskaya, N

“…Background  Numerous studies have demonstrated the beneficial effect of Avène Thermal Spring Water (TSW) in dermatological diseases but the molecular…”
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Ca2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells by Vanoverberghe, K, Vanden Abeele, F, Mariot, P, Lepage, G, Roudbaraki, M, Bonnal, J L, Mauroy, B, Shuba, Y, Skryma, R, Prevarskaya, N

“…Neuroendocrine (NE) differentiation is a hallmark of advanced, androgen-independent prostate cancer, for which there is no successful therapy. NE tumor cells…”
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Differential role of TRP channels in prostate cancer by Prevarskaya, N, Flourakis, M, Bidaux, G, Thebault, S, Skryma, R

“…A major clinical problem with PC (prostate cancer) is the cell's ability to survive and proliferate upon androgen withdrawal. Indeed, deregulated cell…”
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Store-operated Ca2+ channels in prostate cancer epithelial cells: function, regulation, and role in carcinogenesis by Vanden Abeele, F, Shuba, Y, Roudbaraki, M, Lemonnier, L, Vanoverberghe, K, Mariot, P, Skryma, R, Prevarskaya, N

“…Ca2+ homeostasis mechanisms, in which the Ca2+ entry pathways play a key role, are critically involved in both normal function and cancerous transformation of…”
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2-APB inhibits volume-regulated anion channels independently from intracellular calcium signaling modulation by Lemonnier, L., Prevarskaya, N., Mazurier, J., Shuba, Y., Skryma, R.

“…It has previously been suggested that volume-regulated anion channels (VRACs) and store-operated channels (SOCs) interact with each other according to their…”
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Alterations in the regulatory volume decrease (RVD) and swelling-activated Cl−current associated with neuroendocrine differentiation of prostate cancer epithelial cells by Lemonnier, L, Lazarenko, R, Shuba, Y, Thebault, S, Roudbaraki, M, Lepage, G, Prevarskaya, N, Skryma, R

“…Neuroendocrine (NE) differentiation of prostate epithelial/basal cells is a hallmark of advanced, androgen-independent prostate cancer, for which there is no…”
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Volume-regulated chloride conductance in the LNCaP human prostate cancer cell line by Shuba, Y M, Prevarskaya, N, Lemonnier, L, Van Coppenolle, F, Kostyuk, P G, Mauroy, B, Skryma, R

“…Patch-clamp recordings were used to study ion currents induced by cell swelling caused by hypotonicity in human prostate cancer epithelial cells, LNCaP. The…”
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A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3 by Ivanov, D.V., Tyazhelova, T.V., Lemonnier, L., Kononenko, N., Pestova, A.A., Nikitin, E.A., Prevarskaya, N., Skryma, R., Panchin, Y.V., Yankovsky, N.K., Baranova, A.V.

“…We report the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3. This gene includes three exons and has two alternatively spliced…”
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Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells by Sydorenko, V, Shuba, Y, Thebault, S, Roudbaraki, M, Lepage, G, Prevarskaya, N, Skryma, R

“…Although the prostate gland is a rich source of α1-adreno- (α1-AR) and m1-cholino receptors (m1-AChR), the membrane processes associated with their…”
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Verapamil inhibits proliferation of LNCaP human prostate cancer cells influencing K+ channel gating by Rybalchenko, V, Prevarskaya, N, Van Coppenolle, F, Legrand, G, Lemonnier, L, Le Bourhis, X, Skryma, R

“…The mechanisms of verapamil and tetraethylammonium (TEA) inhibition of voltage-gated K+ channels in LNCaP human prostate cancer cells were studied in…”
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Prolactin stimulates cell proliferation through a long form of prolactin receptor and K+ channel activation by Van Coppenolle, Fabien, Skryma, Roman, Ouadid-Ahidouch, Halima, Slomianny, Christian, Roudbaraki, Morad, Delcourt, Philippe, Dewailly, Etienne, Humez, Sandrine, Crépin, Alexandre, Gourdou, Isabelle, Djiane, Jean, Bonnal, Jean-Louis, Mauroy, Brigitte, Prevarskaya, Natalia

“…PRL (prolactin) has been implicated in the proliferation and differentiation of numerous tissues, including the prostate gland. However, the PRL-R (PRL…”
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Potassium conductance in the androgen-sensitive prostate cancer cell line, LNCaP: Involvement in cell proliferation by Skryma, Roman N., Prevarskaya, Natalia B., Dufy-Barbe, Luce, Odessa, Marie F., Audin, Jacques, Dufy, Bernard

“…BACKGROUND Very little is known about the expression of ion channels in prostate cells (both normal and malignant), and their possible role in physiological…”
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TRP channels in agonist-induced proliferation of prostate cancer cells by Shuba, Y. M., Skryma, R., Prevarskaya, N.

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