Search Results - "Skryabin, Boris"

DNA barcoding reveals that injected transgenes are predominantly processed by homologous recombination in mouse zygote by Smirnov, Alexander, Fishman, Veniamin, Yunusova, Anastasia, Korablev, Alexey, Serova, Irina, Skryabin, Boris V, Rozhdestvensky, Timofey S, Battulin, Nariman

“…Abstract Mechanisms that ensure repair of double-strand DNA breaks (DSBs) are instrumental in the integration of foreign DNA into the genome of transgenic…”
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Differential effects of anoctamins on intracellular calcium signals by Cabrita, Inês, Benedetto, Roberta, Fonseca, Ana, Wanitchakool, Podchanart, Sirianant, Lalida, Skryabin, Boris V., Schenk, Laura K., Pavenstädt, Hermann, Schreiber, Rainer, Kunzelmann, Karl

“…ABSTRACT The Ca2+‐activated Cl‒ channel TMEM16A [anoctamin (ANO)1] is homologous to yeast Ist2 and has been shown to tether the cortical endoplasmic reticulum…”
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Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure by Špiranec, Katarina, Chen, Wen, Werner, Franziska, Nikolaev, Viacheslav O, Naruke, Takashi, Koch, Franziska, Werner, Andrea, Eder-Negrin, Petra, Diéguez-Hurtado, Rodrigo, Adams, Ralf H, Baba, Hideo A, Schmidt, Hannes, Schuh, Kai, Skryabin, Boris V, Movahedi, Kiavash, Schweda, Frank, Kuhn, Michaela

“…BACKGROUND:Peripheral vascular resistance has a major impact on arterial blood pressure levels. Endothelial C-type natriuretic peptide (CNP) participates in…”
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Reference Genes across Nine Brain Areas of Wild Type and Prader-Willi Syndrome Mice: Assessing Differences in Igfbp7 , Pcsk1 , Nhlh2 and Nlgn3 Expression by Kummerfeld, Delf-Magnus, Skryabin, Boris V, Brosius, Juergen, Vakhrushev, Sergey Y, Rozhdestvensky, Timofey S

“…Prader−Willi syndrome (PWS) is a complex neurodevelopmental disorder caused by the deletion or inactivation of paternally expressed imprinted genes at the…”
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A universal approach to investigate circRNA protein coding function by Mo, Dingding, Li, Xinping, Raabe, Carsten A., Cui, Di, Vollmar, Jeanne-Franca, Rozhdestvensky, Timofey S., Skryabin, Boris V., Brosius, Juergen

“…Circular RNAs (circRNAs) are an emerging class of RNA molecules that have been linked to human diseases and important regulatory pathways. Their functional…”
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The Receptor for Advanced Glycation Endproducts (RAGE) Contributes to Severe Inflammatory Liver Injury in Mice by Weinhage, Toni, Wirth, Timo, Schütz, Paula, Becker, Philipp, Lueken, Aloys, Skryabin, Boris V, Wittkowski, Helmut, Foell, Dirk

“…The receptor for advanced glycation end products (RAGE) is a multiligand receptor involved in a number of processes and disorders. While it is known that…”
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Pervasive head-to-tail insertions of DNA templates mask desired CRISPR-Cas9-mediated genome editing events by Skryabin, Boris V, Kummerfeld, Delf-Magnus, Gubar, Leonid, Seeger, Birte, Kaiser, Helena, Stegemann, Anja, Roth, Johannes, Meuth, Sven G, Pavenstädt, Hermann, Sherwood, Joanna, Pap, Thomas, Wedlich-Söldner, Roland, Sunderkötter, Cord, Schwartz, Yuri B, Brosius, Juergen, Rozhdestvensky, Timofey S

“…CRISPR-Cas9-mediated homology-directed DNA repair is the method of choice for precise gene editing in a wide range of model organisms, including mouse and…”
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A Comprehensive Review of Genetically Engineered Mouse Models for Prader-Willi Syndrome Research by Kummerfeld, Delf-Magnus, Raabe, Carsten A, Brosius, Juergen, Mo, Dingding, Skryabin, Boris V, Rozhdestvensky, Timofey S

“…Prader-Willi syndrome (PWS) is a neurogenetic multifactorial disorder caused by the deletion or inactivation of paternally imprinted genes on human chromosome…”
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Advancing 3Rs: The Mouse Estrus Detector (MED) as a Low-Stress, Painless, and Efficient Tool for Estrus Determination in Mice by Belozertseva, Irina V, Merkulovs, Dmitrijs D, Kaiser, Helena, Rozhdestvensky, Timofey S, Skryabin, Boris V

“…Determining the estrous cycle stages in mice is essential for optimizing breeding strategies, synchronizing experimental timelines, and facilitating studies in…”
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A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models by Frank, Stefan, Skryabin, Boris V, Greber, Boris

“…Transcription activator-like effector nucleases (TALENs) have emerged as a tool for enabling targeted gene editing and disruption in difficult systems, such as…”
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Impaired myocellular Ca2+ cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation by Glaser, Dennis, Heinick, Alexander, Herting, Julius R., Massing, Fabian, Müller, Frank U., Pauls, Paul, Rozhdestvensky, Timofey S., Schulte, Jan S., Seidl, Matthias D., Skryabin, Boris V., Stümpel, Frank, Kirchhefer, Uwe

“…The activity of protein phosphatase 2A (PP2A) is determined by the expression and localization of the regulatory B-subunits. PP2A-B56α is the dominant isoform…”
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Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine by Schreiber, Rainer, Faria, Diana, Skryabin, Boris V., Wanitchakool, Podchanart, Rock, Jason R., Kunzelmann, Karl

“…Intestinal epithelial electrolyte secretion is activated by increase in intracellular cAMP or Ca 2+ and opening of apical Cl − channels. In infants and young…”
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Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2 by Schmeisser, Michael J., Ey, Elodie, Wegener, Stephanie, Bockmann, Juergen, Stempel, A. Vanessa, Kuebler, Angelika, Janssen, Anna-Lena, Udvardi, Patrick T., Shiban, Ehab, Spilker, Christina, Balschun, Detlef, Skryabin, Boris V., Dieck, Susanne tom, Smalla, Karl-Heinz, Montag, Dirk, Leblond, Claire S., Faure, Philippe, Torquet, Nicolas, Le Sourd, Anne-Marie, Toro, Roberto, Grabrucker, Andreas M., Shoichet, Sarah A., Schmitz, Dietmar, Kreutz, Michael R., Bourgeron, Thomas, Gundelfinger, Eckart D., Boeckers, Tobias M.

“…Altered glutamatergic neurotransmission can lead to the core symptoms of autism, and ProSAP1/Shank2 and ProSAP2/Shank3 proteins seem to serve different…”
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MicroRNA expression in the adult mouse central nervous system by Bak, Mads, Silahtaroglu, Asli, Møller, Morten, Christensen, Mette, Rath, Martin F, Skryabin, Boris, Tommerup, Niels, Kauppinen, Sakari

“…MicroRNAs are approximately 22 nucleotide endogenous noncoding RNAs that post-transcriptionally repress expression of protein-coding genes by base-pairing with…”
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DHHC7-mediated palmitoylation of the accessory protein barttin critically regulates the functions of ClC-K chloride channels by Gorinski, Nataliya, Wojciechowski, Daniel, Guseva, Daria, Abdel Galil, Dalia, Mueller, Franziska E., Wirth, Alexander, Thiemann, Stefan, Zeug, Andre, Schmidt, Silke, Zareba-Kozioł, Monika, Wlodarczyk, Jakub, Skryabin, Boris V., Glage, Silke, Fischer, Martin, Al-Samir, Samer, Kerkenberg, Nicole, Hohoff, Christa, Zhang, Weiqi, Endeward, Volker, Ponimaskin, Evgeni

“…Barttin is the accessory subunit of the human ClC-K chloride channels, which are expressed in both the kidney and inner ear. Barttin promotes trafficking of…”
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Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation by Skryabin, Boris V, Gubar, Leonid V, Seeger, Birte, Pfeiffer, Jana, Handel, Sergej, Robeck, Thomas, Karpova, Elena, Rozhdestvensky, Timofey S, Brosius, Jürgen

“…Prader-Willi syndrome (PWS [MIM 176270]) is a neurogenetic disorder characterized by decreased fetal activity, muscular hypotonia, failure to thrive, short…”
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Ectopic expression of Snord115 in choroid plexus interferes with editing but not splicing of 5-Ht2c receptor pre-mRNA in mice by Raabe, Carsten A., Voss, Reinhard, Kummerfeld, Delf-Magnus, Brosius, Juergen, Galiveti, Chenna R., Wolters, Anna, Seggewiss, Jochen, Huge, Andreas, Skryabin, Boris V., Rozhdestvensky, Timofey S.

“…Serotonin 5-HT2C receptor is a G-protein coupled excitatory receptor that regulates several biochemical pathways and has been implicated in obesity, mental…”
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SNORD116 and growth hormone therapy impact IGFBP7 in Prader–Willi syndrome by Eddiry, Sanaa, Diene, Gwenaelle, Molinas, Catherine, Salles, Juliette, Auriol, Françoise Conte, Gennero, Isabelle, Bieth, Eric, Skryabin, Boris V., Rozhdestvensky, Timofey S., Burnett, Lisa C., Leibel, Rudolph L., Tauber, Maithé, Salles, Jean Pierre

“…Purpose Prader–Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the…”
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Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia by Bork, Nadja I., Kuret, Anna, Cruz Santos, Melanie, Molina, Cristina E., Reiter, Beate, Reichenspurner, Hermann, Friebe, Andreas, Skryabin, Boris V., Rozhdestvensky, Timofey S., Kuhn, Michaela, Lukowski, Robert, Nikolaev, Viacheslav O.

“…3′,5′-cyclic guanosine monophosphate (cGMP) is a druggable second messenger regulating cell growth and survival in a plethora of cells and disease states, many…”
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Neuronal expression of the human neuropeptide S receptor NPSR1 identifies NPS-induced calcium signaling pathways by Erdmann, Frank, Kügler, Sebastian, Blaesse, Peter, Lange, Maren D, Skryabin, Boris V, Pape, Hans-Christian, Jüngling, Kay

“…The neuropeptide S (NPS) system was discovered as a novel neurotransmitter system a decade ago and has since been identified as a key player in the modulation…”
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