Search Results - "Skružný, Michal"

The endocytic protein machinery as an actin-driven membrane-remodeling machine by Skruzny, Michal

“…In clathrin-mediated endocytosis, a principal membrane trafficking route of all eukaryotic cells, forces are applied to invaginate the plasma membrane and form…”
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Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis by Skruzny, Michal, Brach, Thorsten, Ciuffa, Rodolfo, Rybina, Sofia, Wachsmuth, Malte, Kaksonen, Marko

“…Dynamic actin filaments are a crucial component of clathrin-mediated endocytosis when endocytic proteins cannot supply enough energy for vesicle budding. Actin…”
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The protein architecture of the endocytic coat analyzed by FRET microscopy by Skruzny, Michal, Pohl, Emma, Gnoth, Sandina, Malengo, Gabriele, Sourjik, Victor

“…Endocytosis is a fundamental cellular trafficking pathway, which requires an organized assembly of the multiprotein endocytic coat to pull the plasma membrane…”
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Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis by Lizarrondo, Javier, Klebl, David P., Niebling, Stephan, Abella, Marc, Schroer, Martin A., Mertens, Haydyn D. T., Veith, Katharina, Thuenauer, Roland, Svergun, Dmitri I., Skruzny, Michal, Sobott, Frank, Muench, Stephen P., Garcia-Alai, Maria M.

“…During clathrin-mediated endocytosis, a complex and dynamic network of protein-membrane interactions cooperate to achieve membrane invagination. Throughout…”
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Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast by Defelipe, Lucas A., Veith, Katharina, Burastero, Osvaldo, Kupriianova, Tatiana, Bento, Isabel, Skruzny, Michal, Kölbel, Knut, Uetrecht, Charlotte, Thuenauer, Roland, García-Alai, Maria M.

“…Clathrin forms a triskelion, or three-legged, network that regulates cellular processes by facilitating cargo internalization and trafficking in eukaryotes…”
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Epsin and Sla2 form assemblies through phospholipid interfaces by Garcia-Alai, Maria M., Heidemann, Johannes, Skruzny, Michal, Gieras, Anna, Mertens, Haydyn D. T., Svergun, Dmitri I., Kaksonen, Marko, Uetrecht, Charlotte, Meijers, Rob

“…In clathrin-mediated endocytosis, adapter proteins assemble together with clathrin through interactions with specific lipids on the plasma membrane. However,…”
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FRET Microscopy in Yeast by Skruzny, Michal, Pohl, Emma, Abella, Marc

“…Förster resonance energy transfer (FRET) microscopy is a powerful fluorescence microscopy method to study the nanoscale organization of multiprotein assemblies…”
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An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes by Skruzný, Michal, Schneider, Claudia, Rácz, Attila, Weng, Julan, Tollervey, David, Hurt, Ed

“…Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle (mRNP)…”
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An Organized Co-assembly of Clathrin Adaptors Is Essential for Endocytosis by Skruzny, Michal, Desfosses, Ambroise, Prinz, Simone, Dodonova, Svetlana O., Gieras, Anna, Uetrecht, Charlotte, Jakobi, Arjen J., Abella, Marc, Hagen, Wim J.H., Schulz, Joachim, Meijers, Rob, Rybin, Vladimir, Briggs, John A.G., Sachse, Carsten, Kaksonen, Marko

“…Clathrin-mediated endocytosis, the main trafficking route from the plasma membrane to the cytoplasm, is critical to many fundamental cellular processes…”
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Prp45 affects Prp22 partition in spliceosomal complexes and splicing efficiency of non-consensus substrates by Gahura, Ondřej, Abrhámová, Kateřina, Skružný, Michal, Valentová, Anna, Munzarová, Vanda, Folk, Petr, Půta, František

“…Human transcription co‐regulator SNW1/SKIP is implicated in the regulation of both transcription elongation and alternative splicing. Prp45, the SNW/SKIP…”
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Actin-generated force applied during endocytosis measured by Sla2-based FRET tension sensors by Abella, Marc, Andruck, Lynell, Malengo, Gabriele, Skruzny, Michal

“…Mechanical forces are integral to many cellular processes, including clathrin-mediated endocytosis, a principal membrane trafficking route into the cell…”
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Functional Mapping of Saccharomyces cerevisiae Prp45 Identifies the SNW Domain as Essential for Viability by Martinkova, Katerina, Lebduska, Pavel, Skruzny, Michal, Folk, Petr, Puta, Frantisek

“…The essential gene product Prp45 (379 aa) of Saccharomyces cerevisiae is a highly conserved, but N-terminally abridged, ortholog of the human transcriptional…”
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Nanoscale structural organization and stoichiometry of the budding yeast kinetochore by Cieslinski, Konstanty, Wu, Yu-Le, Nechyporenko, Lisa, Hörner, Sarah Janice, Conti, Duccio, Skruzny, Michal, Ries, Jonas

“…Proper chromosome segregation is crucial for cell division. In eukaryotes, this is achieved by the kinetochore, an evolutionarily conserved multiprotein…”
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The Fission Yeast Ortholog of the Coregulator SKIP Interacts with the Small Subunit of U2AF by Ambrozková, Monika, Půta, František, Fuková, Iva, Skružný, Michal, Brábek, Jan, Folk, Petr

“…The mode of action of transcriptional coregulators may involve the recruitment of spliceosome components. Using the two-hybrid screen, we examined the…”
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Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis by Skruzny, Michal, Brach, Thorsten, Ciuffa, Rodolfo, Rybina, Sofia, Wachsmuth, Malte, Kaksonen, Marko

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An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes: e1000008 by Skruzný, Michal, Schneider, Claudia, Rácz, Attila, Weng, Julan, Tollervey, David, Hurt, Ed

“…Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle (mRNP)…”
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Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe by Skružný, Michal, Ambrozková, Monika, Fuková, Iva, Martı́nková, Kateřina, Blahůšková, Anna, Hamplová, Ludmila, Půta, František, Folk, Petr

“…We screened the Dictyostelium discoideum two-hybrid cDNA library with the SNW/SKIP transcription coregulator SnwA and identified a novel cyclophilin CypE…”
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