Search Results - "Skowronski, Danuta M."

Repeated annual influenza vaccination and vaccine effectiveness: review of evidence by Belongia, Edward A, Skowronski, Danuta M, McLean, Huong Q, Chambers, Catharine, Sundaram, Maria E, De Serres, Gaston

“…Studies in the 1970s and 1980s signaled concern that repeated influenza vaccination could affect vaccine protection. The antigenic distance hypothesis provided…”
Get full text

A Perfect Storm: Impact of Genomic Variation and Serial Vaccination on Low Influenza Vaccine Effectiveness During the 2014–2015 Season by Skowronski, Danuta M., Chambers, Catharine, Sabaiduc, Suzana, De Serres, Gaston, Winter, Anne-Luise, Dickinson, James A., Krajden, Mel, Gubbay, Jonathan B., Drews, Steven J., Martineau, Christine, Eshaghi, Alireza, Kwindt, Trijntje L., Bastien, Nathalie, Li, Yan

“…Background. The 2014–2015 influenza season was distinguished by an epidemic of antigenically-drifted A(H3N2) viruses and vaccine components identical to…”
Get full text

Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses by Skowronski, Danuta M, Janjua, Naveed Z, De Serres, Gaston, Sabaiduc, Suzana, Eshaghi, Alireza, Dickinson, James A, Fonseca, Kevin, Winter, Anne-Luise, Gubbay, Jonathan B, Krajden, Mel, Petric, Martin, Charest, Hugues, Bastien, Nathalie, Kwindt, Trijntje L, Mahmud, Salaheddin M, Van Caeseele, Paul, Li, Yan

“…Influenza vaccine effectiveness (VE) is generally interpreted in the context of vaccine match/mismatch to circulating strains with evolutionary drift in the…”
Get full text

Serial cross-sectional estimation of vaccine-and infection-induced SARS-CoV-2 seroprevalence in British Columbia, Canada by Skowronski, Danuta M, Kaweski, Samantha E, Irvine, Michael A, Kim, Shinhye, Chuang, Erica S Y, Sabaiduc, Suzana, Fraser, Mieke, Reyes, Romina C, Henry, Bonnie, Levett, Paul N, Petric, Martin, Krajden, Mel, Sekirov, Inna

“…The evolving proportion of the population considered immunologically naive versus primed for more efficient immune memory response to SARS-CoV-2 has…”
Get full text

Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015 by Skowronski, Danuta M., Chambers, Catharine, De Serres, Gaston, Sabaiduc, Suzana, Winter, Anne-Luise, Dickinson, James A., Gubbay, Jonathan B., Fonseca, Kevin, Drews, Steven J., Charest, Hugues, Martineau, Christine, Krajden, Mel, Petric, Martin, Bastien, Nathalie, Li, Yan, Smith, Derek J.

“…Background. The antigenic distance hypothesis (ADH) predicts that negative interference from prior season's influenza vaccine (v1) on the current season's…”
Get full text

Single-dose mRNA Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Including Alpha and Gamma Variants: A Test-negative Design in Adults 70 Years and Older in British Columbia, Canada by Skowronski, Danuta M, Setayeshgar, Solmaz, Zou, Macy, Prystajecky, Natalie, Tyson, John R, Galanis, Eleni, Naus, Monika, Patrick, David M, Sbihi, Hind, El Adam, Shiraz, Henry, Bonnie, Hoang, Linda M N, Sadarangani, Manish, Jassem, Agatha N, Krajden, Mel

“…Abstract Background Randomized-controlled trials of messenger RNA (mRNA) vaccine protection against severe acute respiratory syndrome coronavirus 2…”
Get full text

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada by Skowronski, Danuta M, De Serres, Gaston, Crowcroft, Natasha S, Janjua, Naveed Z, Boulianne, Nicole, Hottes, Travis S, Rosella, Laura C, Dickinson, James A, Gilca, Rodica, Sethi, Pam, Ouhoummane, Najwa, Willison, Donald J, Rouleau, Isabelle, Petric, Martin, Fonseca, Kevin, Drews, Steven J, Rebbapragada, Anuradha, Charest, Hugues, Hamelin, Marie-Eve, Boivin, Guy, Gardy, Jennifer L, Li, Yan, Kwindt, Trijntje L, Patrick, David M, Brunham, Robert C

“…In late spring 2009, concern was raised in Canada that prior vaccination with the 2008-09 trivalent inactivated influenza vaccine (TIV) was associated with…”
Get full text

Influenza Vaccination of Healthcare Workers: Critical Analysis of the Evidence for Patient Benefit Underpinning Policies of Enforcement by De Serres, Gaston, Skowronski, Danuta M, Ward, Brian J, Gardam, Michael, Lemieux, Camille, Yassi, Annalee, Patrick, David M, Krajden, Mel, Loeb, Mark, Collignon, Peter, Carrat, Fabrice

“…Four cluster randomized controlled trials (cRCTs) conducted in long-term care facilities (LTCFs) have reported reductions in patient risk through increased…”
Get full text

Early season co-circulation of influenza A(H3N2) and B(Yamagata): interim estimates of 2017/18 vaccine effectiveness, Canada, January 2018 by Skowronski, Danuta M, Chambers, Catharine, De Serres, Gaston, Dickinson, James A, Winter, Anne-Luise, Hickman, Rebecca, Chan, Tracy, Jassem, Agatha N, Drews, Steven J, Charest, Hugues, Gubbay, Jonathan B, Bastien, Nathalie, Li, Yan, Krajden, Mel

“…Using a test-negative design, we assessed interim vaccine effectiveness (VE) for the 2017/18 epidemic of co-circulating influenza A(H3N2) and B(Yamagata)…”
Get full text

Paradoxical clade- and age-specific vaccine effectiveness during the 2018/19 influenza A(H3N2) epidemic in Canada: potential imprint-regulated effect of vaccine (I-REV) by Skowronski, Danuta M, Sabaiduc, Suzana, Leir, Siobhan, Rose, Caren, Zou, Macy, Murti, Michelle, Dickinson, James A, Olsha, Romy, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Bastien, Nathalie, Li, Yan, Jassem, Agatha, Krajden, Mel, De Serres, Gaston

“…Introduction The Canadian Sentinel Practitioner Surveillance Network reports vaccine effectiveness (VE) for the 2018/19 influenza A(H3N2) epidemic. Aim To…”
Get full text

Previous infection with seasonal coronaviruses does not protect male Syrian hamsters from challenge with SARS-CoV-2 by Francis, Magen E., Jansen, Ethan B., Yourkowski, Anthony, Selim, Alaa, Swan, Cynthia L., MacPhee, Brian K., Thivierge, Brittany, Buchanan, Rachelle, Lavender, Kerry J., Darbellay, Joseph, Rogers, Matthew B., Lew, Jocelyne, Gerdts, Volker, Falzarano, Darryl, Skowronski, Danuta M., Sjaarda, Calvin, Kelvin, Alyson A.

“…SARS-CoV-2 variants and seasonal coronaviruses continue to cause disease and coronaviruses in the animal reservoir pose a constant spillover threat…”
Get full text

Interim estimates of 2018/19 vaccine effectiveness against influenza A(H1N1)pdm09, Canada, January 2019 by Skowronski, Danuta M, Leir, Siobhan, Sabaiduc, Suzana, Murti, Michelle, Dickinson, James A, Olsha, Romy, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Chan, Tracy, Bastien, Nathalie, Li, Yan, Krajden, Mel, De Serres, Gaston

“…Using a test-negative design, the Canadian Sentinel Practitioner Surveillance Network assessed interim 2018/19 vaccine effectiveness (VE) against predominant…”
Get full text

Interim estimates of 2019/20 vaccine effectiveness during early-season co-circulation of influenza A and B viruses, Canada, February 2020 by Skowronski, Danuta M, Zou, Macy, Sabaiduc, Suzana, Murti, Michelle, Olsha, Romy, Dickinson, James A, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Jassem, Agatha, Krajden, Mel, Bastien, Nathalie, Li, Yan, De Serres, Gaston

“…Interim results from Canada's Sentinel Practitioner Surveillance Network show that during a season characterised by early co-circulation of influenza A and B…”
Get full text

Network theory and SARS: predicting outbreak diversity by Meyers, Lauren Ancel, Pourbohloul, Babak, Newman, M.E.J., Skowronski, Danuta M., Brunham, Robert C.

“…Many infectious diseases spread through populations via the networks formed by physical contacts among individuals. The patterns of these contacts tend to be…”
Get full text

Integrated Sentinel Surveillance Linking Genetic, Antigenic, and Epidemiologic Monitoring of Influenza Vaccine-Virus Relatedness and Effectiveness During the 2013-2014 Influenza Season by Skowronski, Danuta M., Chambers, Catharine, Sabaiduc, Suzana, De Serres, Gaston, Winter, Anne-Luise, Dickinson, James A., Gubbay, Jonathan, Fonseca, Kevin, Charest, Hugues, Krajden, Mel, Petric, Martin, Mahmud, Salaheddin M., Van Caeseele, Paul, Bastien, Nathalie, Eshaghi, Alireza, Li, Yan

“…Background. Canada's Sentinel Physician Surveillance Network links genetic, antigenic, and vaccine effectiveness (VE) measures in an integrated platform of…”
Get full text

Component-Specific Effectiveness of Trivalent Influenza Vaccine as Monitored through a Sentinel Surveillance Network in Canada, 2006–2007 by Skowronski, Danuta M., De Serres, Gaston, Dickinson, Jim, Petric, Martin, Mak, Annie, Fonseca, Kevin, Kwindt, Trijntje L., Chan, Tracy, Bastien, Nathalie, Charest, Hugues, Li, Yan

“…Background. Trivalent inactivated influenza vaccine (TIV) is reformulated annually to contain representative strains of 2 influenza A subtypes (H1N1 and H3N2)…”
Get full text

Largest Measles Epidemic in North America in a Decade—Quebec, Canada, 2011: Contribution of Susceptibility, Serendipity, and Superspreading Events by De Serres, Gaston, Markowski, France, Toth, Eveline, Landry, Monique, Auger, Danielle, Mercier, Marlène, Bélanger, Philippe, Turmel, Bruno, Arruda, Horacio, Boulianne, Nicole, Ward, Brian J., Skowronski, Danuta M.

“…Background. The largest measles epidemic in North America in the last decade, occurred in 2011 in Quebec, Canada, where rates of 1- and 2-dose vaccine coverage…”
Get full text

Rapid Decline of Influenza Vaccine—Induced Antibody in the Elderly: Is It Real, or Is It Relevant? by Skowronski, Danuta M., Tweed, S. Aleina, De Serres, Gaston

“…Advisory committees have cautioned that influenza vaccine-induced antibody declines more rapidly in the elderly, falling below seroprotective levels within 4…”
Get full text

Adaptive immune responses to two-dose COVID-19 vaccine series in healthy Canadian adults ≥ 50 years: a prospective, observational cohort study by Gaultier, Gabrielle N., McMillan, Brynn, Poloni, Chad, Lo, Mandy, Cai, Bing, Zheng, Jean J., Baer, Hannah M., Shulha, Hennady P., Simmons, Karen, Márquez, Ana Citlali, Bartlett, Sofia R., Cook, Laura, Levings, Megan K., Steiner, Theodore, Sekirov, Inna, Zlosnik, James E. A., Morshed, Muhammad, Skowronski, Danuta M., Krajden, Mel, Jassem, Agatha N., Sadarangani, Manish

“…To evaluate immune responses to COVID-19 vaccines in adults aged 50 years and older, spike protein (S)-specific antibody concentration, avidity, and function…”
Get full text

Cross-reactive and Vaccine-Induced Antibody to an Emerging Swine-Origin Variant of Influenza A Virus Subtype H3N2 (H3N2v) by Skowronski, Danuta M., Janjua, Naveed Z., De Serres, Gaston, Purych, Dale, Gilca, Vladimir, Scheifele, David W., Dionne, Marc, Sabaiduc, Suzana, Gardy, Jennifer L., Li, Guiyun, Bastien, Nathalie, Petric, Martin, Boivin, Guy, Li, Yan

“…Background. Cases of infection due to a novel swine-origin variant of influenza A virus subtype H3N2 (H3N2v) have recently been identified in the United…”
Get full text