Search Results - "Skowronski, Danuta"
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Published in The New England journal of medicine (22-04-2021)“…To the Editor: Polack et al. (Dec. 31) 1 report a vaccine efficacy of 94.8% against Covid-19 after two doses of the messenger RNA (mRNA) vaccine BNT162b2…”
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Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses
Published in PloS one (25-03-2014)“…Influenza vaccine effectiveness (VE) is generally interpreted in the context of vaccine match/mismatch to circulating strains with evolutionary drift in the…”
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Protection against omicron (B.1.1.529) BA.2 reinfection conferred by primary omicron BA.1 or pre-omicron SARS-CoV-2 infection among health-care workers with and without mRNA vaccination: a test-negative case-control study
Published in The Lancet infectious diseases (01-01-2023)“…There is a paucity of data on vaccine-induced or infection-induced (hybrid or natural) immunity against omicron (B.1.1.529) subvariant BA.2, particularly in…”
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Repeated annual influenza vaccination and vaccine effectiveness: review of evidence
Published in Expert review of vaccines (03-07-2017)“…Studies in the 1970s and 1980s signaled concern that repeated influenza vaccination could affect vaccine protection. The antigenic distance hypothesis provided…”
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Role of Egg-adaptation Mutations in Low Influenza A(H3N2) Vaccine Effectiveness During the 2012-2013 Season
Published in Clinical infectious diseases (15-10-2018)Get full text
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Serial cross-sectional estimation of vaccine-and infection-induced SARS-CoV-2 seroprevalence in British Columbia, Canada
Published in Canadian Medical Association journal (CMAJ) (05-12-2022)“…The evolving proportion of the population considered immunologically naive versus primed for more efficient immune memory response to SARS-CoV-2 has…”
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Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada
Published in PLoS medicine (01-04-2010)“…In late spring 2009, concern was raised in Canada that prior vaccination with the 2008-09 trivalent inactivated influenza vaccine (TIV) was associated with…”
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Influenza Vaccination of Healthcare Workers: Critical Analysis of the Evidence for Patient Benefit Underpinning Policies of Enforcement
Published in PloS one (27-01-2017)“…Four cluster randomized controlled trials (cRCTs) conducted in long-term care facilities (LTCFs) have reported reductions in patient risk through increased…”
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A Perfect Storm: Impact of Genomic Variation and Serial Vaccination on Low Influenza Vaccine Effectiveness During the 2014–2015 Season
Published in Clinical infectious diseases (01-07-2016)“…Background. The 2014–2015 influenza season was distinguished by an epidemic of antigenically-drifted A(H3N2) viruses and vaccine components identical to…”
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Serial Vaccination and the Antigenic Distance Hypothesis: Effects on Influenza Vaccine Effectiveness During A(H3N2) Epidemics in Canada, 2010–2011 to 2014–2015
Published in The Journal of infectious diseases (01-04-2017)“…Background. The antigenic distance hypothesis (ADH) predicts that negative interference from prior season's influenza vaccine (v1) on the current season's…”
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Effectiveness of BNT162b2 Vaccine Against Omicron-SARS-CoV-2 Subvariants in Children 5-11 Years of Age in Quebec, Canada, January 2022 to January 2023
Published in The Pediatric infectious disease journal (01-01-2024)“…In premarketing clinical trials conducted before Omicron emergence, BNT162b2 vaccine efficacy against COVID-19 was 90% in children. We conducted postmarketing…”
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Two-Dose Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Effectiveness With Mixed Schedules and Extended Dosing Intervals: Test-Negative Design Studies From British Columbia and Quebec, Canada
Published in Clinical infectious diseases (30-11-2022)“…The Canadian coronavirus disease 2019 (COVID-19) immunization strategy deferred second doses and allowed mixed schedules. We compared 2-dose vaccine…”
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BNT162b2 Effectiveness Against Delta and Omicron Variants of Severe Acute Respiratory Syndrome Coronavirus 2 in Adolescents Aged 12–17 Years, by Dosing Interval and Duration
Published in The Journal of infectious diseases (26-04-2023)“…Abstract Background Two- and 3-dose BNT162b2 vaccine effectiveness (VE) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,…”
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Single-dose mRNA Vaccine Effectiveness Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Including Alpha and Gamma Variants: A Test-negative Design in Adults 70 Years and Older in British Columbia, Canada
Published in Clinical infectious diseases (09-04-2022)“…Abstract Background Randomized-controlled trials of messenger RNA (mRNA) vaccine protection against severe acute respiratory syndrome coronavirus 2…”
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Influenza Hospitalization Burden by Subtype, Age, Comorbidity, and Vaccination Status: 2012–2013 to 2018–2019 Seasons, Quebec, Canada
Published in Clinical infectious diseases (20-03-2024)“…Abstract Background Influenza immunization programs aim to reduce the risk and burden of severe outcomes. To inform optimal program strategies, we monitored…”
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Serial cross-sectional estimation of vaccineand infection-induced SARS-CoV-2 seroprevalence in British Columbia, Canada
Published in Canadian Medical Association journal (CMAJ) (05-12-2022)“…Background: The evolving proportion of the population considered immunologically naive versus primed for more efficient immune memory response to SARS-CoV-2…”
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Ecological Fallacy, Nonspecific Outcomes, and the Attribution of Disproportionate Vaccine Benefits
Published in Clinical infectious diseases (17-05-2018)Get full text
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Caution Required in the Use of Administrative Data and General Laboratory Submissions for Influenza Vaccine Effectiveness Estimation
Published in Clinical infectious diseases (30-08-2019)Get full text
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Pooling and the Potential Dilution of Repeat Influenza Vaccination Effects
Published in Clinical infectious diseases (15-07-2017)Get full text
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