Search Results - "Skov, Birgit G"
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The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2012)“…Highlights ► The diagnosis of lung cancer involves the identification and complete classification of malignancy. ► New therapeutic options require specific…”
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Paired Comparison of PD-L1 Expression on Cytologic and Histologic Specimens From Malignancies in the Lung Assessed With PD-L1 IHC 28-8pharmDx and PD-L1 IHC 22C3pharmDx
Published in Applied immunohistochemistry & molecular morphology (01-08-2017)“…Programmed cell death ligand-1 (PD-L1) expression is a predictive biomarker for anti-PD-1 immunotherapy in non-small cell lung cancer. Different…”
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Comparison of PD-L1 Expression Using 2 Validated PD-L1 IHC 22C3 pharmDx Methods in Non–Small Cell Lung Cancer in a Routine Hospital Setting
Published in Applied immunohistochemistry & molecular morphology (01-01-2021)“…Concordance between 3 validated, commercial programmed cell death ligand 1 (PD-L1) assays and their associated platforms (PD-L1 IHC 22C3 pharmDx Autostainer…”
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Results of the Randomized Danish Lung Cancer Screening Trial with Focus on High-Risk Profiling
Published in American journal of respiratory and critical care medicine (01-03-2016)“…As of April 2015, participants in the Danish Lung Cancer Screening Trial had been followed for at least 5 years since their last screening. Mortality, causes…”
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Biomarkers in tissue from patients with upper gastrointestinal cancers treated with erlotinib and bevacizumab
Published in Cancer biology & therapy (15-04-2011)“…Malignancies in the upper gastrointestinal (UGI) tract are amongst the most aggressive cancers and only few treatment options exist. We have recently analysed…”
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The prevalence of EGFR mutations in non-small cell lung cancer in an unselected Caucasian population
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-02-2015)“…EGFR mutation frequencies in unselected Caucasian populations are unknown. This study assesses the prevalence of EGFR mutations in an unselected…”
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7
High specificity but low sensitivity of mutation-specific antibodies against EGFR mutations in non-small-cell lung cancer
Published in Modern pathology (01-12-2014)“…Determination of epidermal growth factor receptor (EGFR) mutations has a pivotal impact on treatment of non-small-cell lung cancer (NSCLC). A standardized test…”
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The prevalence of ALK rearrangement in pulmonary adenocarcinomas in an unselected Caucasian population from a defined catchment area: impact of smoking
Published in Histopathology (01-05-2017)“…Aims To assess the prevalence of EML4–ALK rearrangement gene measured by immunohistochemistry in an unselected population‐based consecutive cohort of patients…”
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Multimodality approach to mediastinal staging in non-small cell lung cancer. Faults and benefits of PET-CT: a randomised trial
Published in Thorax (01-04-2011)“…Correct mediastinal staging is a cornerstone in the treatment of patients with non-small cell lung cancer. A large range of methods is available for this…”
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Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-11-2007)“…Summary Purpose C4.4A expression has been implicated in human cancer progression. This protein is a structural homologue of the urokinase receptor, uPAR, which…”
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Endobronchial ultrasound-guided biopsy performed under optimal conditions in patients with known or suspected lung cancer may render mediastinoscopy unnecessary
Published in Journal of bronchology & interventional pulmonology (01-01-2014)“…Mediastinoscopy is the gold standard for preoperative mediastinal staging of patients with suspected or proven lung cancer. Since the development of endoscopic…”
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Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report
Published in BMC research notes (26-11-2013)“…Anaplastic lymphoma kinase-positive non-small cell lung carcinoma patients are generally highly responsive to the dual anaplastic lymphoma kinase and MET…”
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Endoscopic ultrasound guided biopsy versus mediastinoscopy for analysis of paratracheal and subcarinal lymph nodes in lung cancer staging
Published in Lung cancer (Amsterdam, Netherlands) (01-04-2005)“…Exact mediastinal evaluation of patients with non-small-cell lung cancer (NSCLC) is mandatory to improve selection of resectable and curable patients for…”
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Endoscopic ultrasound guided biopsy performed routinely in lung cancer staging spares futile thoracotomies: Preliminary results from a randomised clinical trial
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2005)“…Up to 45% of operations with curative intent for non-small-cell lung cancer (NSCLC) can be regarded as futile, apparently because the stage of the disease is…”
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Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers
Published in Acta oncologica (01-02-2012)“…Patients with upper gastrointestinal cancers have a poor prognosis and only few treatment options. The epidermal growth factor receptor (EGFR) and vascular…”
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High Dermal Mast Cell Prevalence is a Predisposing Factor for Basal Cell Carcinoma in Humans
Published in Journal of investigative dermatology (01-08-2000)“…Ultraviolet B radiation (280–320 nm) can initiate skin cancer as well as suppress the immune system, thereby preventing the rejection of ultraviolet-B-induced…”
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Ground-Glass Opacity Lung Nodules in the Era of Lung Cancer CT Screening: Radiology, Pathology, and Clinical Management
Published in Oncology (Williston Park, N.Y.) (01-03-2016)“…The advent of computed tomography screening for lung cancer will increase the incidence of ground-glass opacity (GGO) nodules detected and referred for…”
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A comparison of endoscopic ultrasound guided biopsy and positron emission tomography with integrated computed tomography in lung cancer staging
Published in Current health sciences journal (01-01-2009)“…Exact staging of patients with non-small-cell lung cancer (NSCLC) is important to improve selection of resectable and curable patients for surgery. Positron…”
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Concomitant occurrence of EGFR -positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report
Published in BMC research notes (26-11-2013)“…Anaplastic lymphoma kinase-positive non-small cell lung carcinoma patients are generally highly responsive to the dual anaplastic lymphoma kinase and MET…”
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Are pathologists biased by clinical information?: A blinded cross-over study of the histopathological diagnosis of mesothelial tumours versus pulmonary adenocarcinoma
Published in Lung cancer (Amsterdam, Netherlands) (01-12-1994)“…In a blinded cross-over design, we studied whether three pathologists were biased by clinical information when making histopathological diagnoses of…”
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