Search Results - "Skoupilová, Hana"
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Harmless glucose‐modified ruthenium complexes suppressing cell migration of highly invasive cancer cell lines
Published in Applied organometallic chemistry (01-01-2020)“…Glucose‐substituted ruthenium complexes [(η6‐benzyl‐glucose)RuCp*]+Cl−, where Cp* = η5‐C5Me5; benzyl‐glucose = peracetylated benzyl β‐d‐glucopyranoside (1),…”
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Electrochemical Study of Highly Substituted Titanocene Dihalides
Published in Electroanalysis (New York, N.Y.) (01-10-2019)“…Titanocene dihalides are promising alternative to Cisplatin in cancer chemotherapy which should reduce negative side effects and overcome increasing resistance…”
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Improving cytotoxic properties of ferrocenes by incorporation of saturated N-heterocycles
Published in Journal of organometallic chemistry (01-10-2017)“…A family of ferrocene derivatives of the general formula [Fe(η5-C5H4CH2(p-C6H4)CH2(N-het))2] bearing saturated six- and five-membered N-heterocycles (N-het)…”
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Ferroptosis as a New Type of Cell Death and its Role in Cancer Treatment
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2018)“…Ferroptosis is a recently discovered type of cell death. It is genetically, morphologically, and biochemically distinct from other types of programmed cell…”
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The Cytotoxic Effect of Newly Synthesized Ferrocenes against Cervical Carcinoma Cells Alone and in Combination with Radiotherapy
Published in Applied sciences (01-06-2020)“…Cervical cancer is one of the most common types of cancer in women, with approximately 500,000 new cases and 250,000 deaths every year. Radiotherapy combined…”
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Cover Feature: Electrochemical Study of Highly Substituted Titanocene Dihalides (Electroanalysis 10/2019)
Published in Electroanalysis (New York, N.Y.) (01-10-2019)“…Titanocene dihalides are promising alternative to Cisplatin in cancer chemotherapy which should reduce negative side effects and overcome increasing resistance…”
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Progress in the Utilisation of Organometallic Compounds in the Development of Cancer Drugs
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (16-10-2019)“…Organometallic compounds are chemical substances containing a carbon-metal bond. From a biological point of view, these compounds are generally considered to…”
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Ferrocenes as Potential Anticancer Drugs: Determination of the Mechanism of Action
Published in Proceedings (01-08-2019)“…Chemotherapy is an essential treatment that still plays a vital role in cancer treatment worldwide. The ferrocene derivatives of the general formula…”
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Ferrocenes as new anticancer drug candidates: Determination of the mechanism of action
Published in European journal of pharmacology (15-01-2020)“…Chemotherapy plays an essential role in the management of cancer worldwide. However, it is a non-specific treatment limited by major drawbacks, thus…”
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Mesoporous silica nanoparticles functionalized with a dialkoxide diorganotin(IV) compound: In search of more selective systems against cancer cells
Published in Microporous and mesoporous materials (15-06-2020)“…Mesoporous silica nanoparticles (MSN) have been functionalized with the polyamino ligand N1-(3-trimethoxysilylpropyl)diethylenetriamine to give the material…”
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Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA
Published in Nucleic acids research (18-02-2016)“…SMC5/6 is a highly conserved protein complex related to cohesin and condensin, which are the key components of higher-order chromatin structures. The SMC5/6…”
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Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells
Published in Cancer investigation (28-05-2017)“…Tamoxifen treatment in breast cancer patients is associated with increased risk of endometrial malignancies. Significantly, higher AGR2 expression was found in…”
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