Search Results - "Skotnicki, Aleksander B."

Alemtuzumab Compared With Chlorambucil As First-Line Therapy for Chronic Lymphocytic Leukemia by HILLMEN, Peter, SKOTNICKI, Aleksander B, ROBAK, Tadeusz, JAKSIC, Branimir, DMOSZYNSKA, Anna, JINGYANG WU, SIRARD, Cynthia, MAYER, Jiri

“…We conducted a randomized trial to evaluate the efficacy and safety of intravenous alemtuzumab compared with chlorambucil in first-line treatment of chronic…”
Get full text

Cladribine, But Not Fludarabine, Added to Daunorubicin and Cytarabine During Induction Prolongs Survival of Patients With Acute Myeloid Leukemia: A Multicenter, Randomized Phase III Study by HOLOWIECKI, Jerzy, GROSICKI, Sebastian, KLOCZKO, Janusz, JEDRZEJCZAK, Wieslaw W, ZDZIARSKA, Barbara, WARZOCHA, Krzysztof, ZAWILSKA, Krystyna, KOMARNICKI, Mieczysław, KIELBINSKI, Marek, PIATKOWSKA-JAKUBAS, Beata, WIERZBOWSKA, Agnieszka, WACH, Malgorzata, GIEBEL, Sebastian, HAUS, Olga, ROBAK, Tadeusz, KYRCZ-KRZEMIEN, Slawomira, KULICZKOWSKI, Kazimierz, SKOTNICKI, Aleksander B, HELLMANN, Andrzej, SULEK, Kazimierz, DMOSZYNSKA, Anna

“…The goal of this study was to evaluate whether the addition of a purine analog, cladribine or fludarabine, to the standard induction regimen affects the…”
Get full text

5-Year Survival in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia in a Randomized, Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen by O'BRIEN, Susan, MOORE, Joseph O, RAI, Kanti R, BOYD, Thomas E, LARRATT, Loree M, SKOTNICKI, Aleksander B, KOZINER, Benjamin, CHANAN-KHAN, Asher A, SEYMOUR, John F, GRIBBEN, John, ITRI, Loretta M

“…A randomized trial of oblimersen plus fludarabine/cyclophosphamide (OBL-FC; n = 120) versus FC (n = 121) was conducted in patients with relapsed/refractory…”
Get full text

Safety of AFM11 in the treatment of patients with B-cell malignancies: findings from two phase 1 studies by Topp, Max, Dlugosz-Danecka, Monika, Skotnicki, Aleksander B, Salogub, Galina, Viardot, Andreas, Klein, Andreas K, Hess, Georg, Michel, Christian S, Grosicki, Sebastian, Gural, Alex, Schwarz, Sylvia E, Pietzko, Kerstin, Gärtner, Ulrike, Strassz, András, Alland, Leila, Mayer, Jiri

“…The prognosis for patients with relapsed and/or refractory (R/R) non-Hodgkin's lymphoma (NHL) or acute lymphoblastic leukaemia (ALL) remains poor, with…”
Get full text

The average relative dose intensity of R‐CHOP is an independent factor determining favorable overall survival in diffuse large B‐cell lymphoma patients by Długosz‐Danecka, Monika, Szmit, Sebastian, Ogórka, Tomasz, Skotnicki, Aleksander B., Jurczak, Wojciech

“…The prognosis of diffuse large B‐cell lymphoma (DLBCL) patients depends on lymphoma‐ and patient‐related risk factors and is best estimated by the…”
Get full text

Primary Cardioprotection Reduces Mortality in Lymphoma Patients with Increased Risk of Anthracycline Cardiotoxicity, Treated by R-CHOP Regimen by Długosz-Danecka, Monika, Gruszka, Alicja M, Szmit, Sebastian, Olszanecka, Agnieszka, Ogórka, Tomasz, Sobociński, Marcin, Jaroszyński, Andrzej, Krawczyk, Katarzyna, Skotnicki, Aleksander B, Jurczak, Wojciech

“…Advances in anti-lymphoma therapy prolong overall survival, making late adverse effects, like doxorubicin-related cardiotoxicity, an even more important…”
Get more information

HGF, sIL-6R and TGF-β1 Play a Significant Role in the Progression of Multiple Myeloma by Jurczyszyn, Artur, Czepiel, Jacek, Biesiada, Grażyna, Gdula-Argasińska, Joanna, Cibor, Dorota, Owczarek, Danuta, Perucki, William, Skotnicki, Aleksander B

“…Background. In the last few years, it has been widely reported that proinflammatory and angiogenic cytokines are important for the development and progression…”
Get full text

Fibrinogen Krakow: a novel hypo/dysfibrinogenemia mutation in fibrinogen gamma chain (Asn325Ile) affecting fibrin clot structure and function by Undas, Anetta, Zdziarska, Joanna, Iwaniec, Teresa, Stepien, Ewa, Skotnicki, Aleksander B, de Moerloose, Philippe, Neerman-Arbez, Marguerite

Get more information

The gain-of-function JAK2 V617F mutation shifts the phenotype of essential thrombocythemia and chronic idiopathic myelofibrosis to more erythremic and less thrombocythemic : A molecular, histologic, and clinical study by RUDZKI, Zbigniew, SACHA, Tomasz, STOJ, Anastazja, CZEKALSKA, Sylwia, WOJCIK, Malgorzata, SKOTNICKI, Aleksander B, GRABOWSKA, Barbara, ZDUNCZYK, Andrzej, OKON, Krzysztof, STACHURA, Jerzy

“…We investigated the prevalence of the JAK2 V617F gain-of-function mutation in patients with Philadelphia chromosome-negative chronic myeloproliferative…”
Get full text

Ferritinemia and serum inflammatory cytokines in Swedish adults with Gaucher disease type 1 by Lorenz, Fryderyk, Pawłowicz, Ewa, Klimkowska, Monika, Beshara, Soheir, Bulanda Brustad, Agnes, Skotnicki, Aleksander B., Wahlin, Anders, Machaczka, Maciej

“…The storage of glucosylceramide in macrophages produces an inflammatory response in Gaucher disease type 1 (GD1) resulting in iron metabolism dysregulation and…”
Get full text

Plasma fatty acid profile in multiple myeloma patients by Jurczyszyn, Artur, Czepiel, Jacek, Gdula-Argasińska, Joanna, Paśko, Paweł, Czapkiewicz, Anna, Librowski, Tadeusz, Perucki, William, Butrym, Aleksandra, Castillo, Jorge J, Skotnicki, Aleksander B

“…Highlights • We noted significant differences in the FA profile of plasma from patients with MM. • Increased levels of saturated and n-6 FA in MM patients…”
Get full text

Status of minimal residual disease after induction predicts outcome in both standard and high‐risk Ph‐negative adult acute lymphoblastic leukaemia. The Polish Adult Leukemia Group ALL 4‐2002 MRD Study by Holowiecki, Jerzy, Krawczyk‐Kulis, Malgorzata, Giebel, Sebastian, Jagoda, Krystyna, Stella‐Holowiecka, Beata, Piatkowska‐Jakubas, Beata, Paluszewska, Monika, Seferynska, Ilona, Lewandowski, Krzysztof, Kielbinski, Marek, Czyz, Anna, Balana‐Nowak, Agnieszka, Król, Maria, Skotnicki, Aleksander B., Jedrzejczak, Wieslaw W., Warzocha, Krzysztof, Lange, Andrzej, Hellmann, Andrzej

“…Summary The treatment of adults with Philadelphia‐negative acute lymphoblastic leukaemia (ALL) depends on the presence of risk factors including age, white…”
Get full text

High-resolution human leukocyte antigen allele and haplotype frequencies of the Polish population based on 20,653 stem cell donors by Schmidt, Alexander H, Solloch, Ute V, Pingel, Julia, Baier, Daniel, Böhme, Irina, Dubicka, Kinga, Schumacher, Stephan, Rutt, Claudia, Skotnicki, Aleksander B, Wachowiak, Jacek, Ehninger, Gerhard

“…Abstract We present high-resolution allele and haplotype frequency (HF) estimations of the Polish population based on more than 20,000 registered stem cell…”
Get full text

Cladribine alone and in combination with cyclophosphamide or cyclophosphamide plus mitoxantrone in the treatment of progressive chronic lymphocytic leukemia: report of a prospective, multicenter, randomized trial of the Polish Adult Leukemia Group (PALG CLL2) by Robak, Tadeusz, Blonski, Jerzy Z., Gora-Tybor, Joanna, Jamroziak, Krzysztof, Dwilewicz-Trojaczek, Jadwiga, Tomaszewska, Agnieszka, Konopka, Lech, Ceglarek, Bernadetta, Dmoszynska, Anna, Kowal, Malgorzata, Kloczko, Janusz, Stella-Holowiecka, Beata, Sulek, Kazimierz, Calbecka, Malgorzata, Zawilska, Krystyna, Kuliczkowski, Kazimierz, Skotnicki, Aleksander B., Warzocha, Krzysztof, Kasznicki, Marek

“…In this prospective randomized trial, we compared the efficacy and toxicity of cladribine (2-CdA) alone to 2-CdA combined with cyclophosphamide (CC) or…”
Get full text

Premature cardiovascular mortality in lymphoma patients treated with (R)-CHOP regimen — A national multicenter study by Jurczak, Wojciech, Szmit, Sebastian, Sobociński, Marcin, Machaczka, Maciej, Drozd-Sokołowska, Joanna, Joks, Monika, Dzietczenia, Justyna, Wróbel, Tomasz, Kumiega, Beata, Zaucha, Jan Maciej, Knopińska-Posłuszny, Wanda, Spychałowicz, Wojciech, Prochwicz, Anna, Drohomirecka, Anna, Skotnicki, Aleksander B

“…Abstract Background Premature cardiovascular mortality related to chemotherapy and occurred in lymphoma survivors before disease progression is one of…”
Get full text

Cutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients by Jurczyszyn, Artur, Olszewska-Szopa, Magdalena, Hungria, Vania, Crusoe, Edvan, Pika, Tomas, Delforge, Michel, Leleu, Xavier, Rasche, Leo, Nooka, Ajay K., Druzd-Sitek, Agnieszka, Walewski, Jan, Davila, Julio, Caers, Jo, Maisnar, Vladimir, Gertz, Morie, Gentile, Massimo, Fantl, Dorotea, Mele, Giuseppe, Vesole, David H., Yee, Andrew J., Shustik, Chaim, Lentzsch, Suzanne, Zweegman, Sonja, Gozzetti, Alessandro, Skotnicki, Aleksander B., Castillo, Jorge J.

“…Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case…”
Get full text

Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukemia Group by Wierzbowska, Agnieszka, Robak, Tadeusz, Pluta, Agnieszka, Wawrzyniak, Ewa, Cebula, Barbara, Hołowiecki, Jerzy, Kyrcz-Krzemień, Sławomira, Grosicki, Sebastian, Giebel, Sebastian, Skotnicki, Aleksander B., Piątkowska-Jakubas, Beata, Kuliczkowski, Kazimierz, Kiełbiński, Marek, Zawilska, Krystyna, Kłoczko, Janusz, Wrzesień-Kuś, Agata

“…Objectives:  Patients with primary refractory AML and with early relapses have unfavorable prognoses and require innovative therapeutic approaches. Purine…”
Get full text

The roles of consolidation and maintenance therapy with novel agents after autologous stem cell transplantation in patients with multiple myeloma by Joks, Monika, Jurczyszyn, Artur, Machaczka, Maciej, Skotnicki, Aleksander B., Komarnicki, Mieczysław

“…Novel agents including immunomodulatory drugs and proteasome inhibitors incorporated into induction regimens and subsequently followed by autologous stem cell…”
Get full text

Bleeding tendency and prolonged wound healing in a patient with A alphaArg16His dysfibrinogenemia: fibrinogen Krakow IV by Zdziarska, Joanna, Iwaniec, Teresa, Undas, Anetta, Skotnicki, Aleksander B

Get full text

Daratumumab--breakthrough drug in multiple myeloma therapy by Jurczyszyn, Artur, Kosmaczewska, Agata, Skotnicki, Aleksander B

“…Multiple myeloma (MM) remains incurable despite important recent advances in treatment. Over the last 2 years, an anti-CD38 monoclonal antibody daratumumab…”
Get full text