Search Results - "Skotheim, RI"

Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs by Rounge, T B, Furu, K, Skotheim, R I, Haugen, T B, Grotmol, T, Enerly, E

“…Small non-coding RNAs play essential roles in gene regulation, however, the interplay between RNA groups, their expression levels and deregulations in…”
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Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1) by Lind, GE, Skotheim, RI, Fraga, MF, Abeler, VM, Esteller, M, Lothe, RA

“…Testicular germ cell tumours (TGCTs) are classified into two main histological subgroups: seminomas and non‐seminomas. The latter comprise several subtypes:…”
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PBX3 is a putative biomarker of aggressive prostate cancer by Ramberg, Håkon, Grytli, Helene Hartvedt, Nygård, Ståle, Wang, Wanzhong, Ögren, Olov, Zhao, Sen, Løvf, Marthe, Katz, Betina, Skotheim, Rolf I., Bjartell, Anders, Eri, Lars Magne, Berge, Viktor, Svindland, Aud, Taskén, Kristin Austlid

“…There is a great need to identify new and better prognostic and predictive biomarkers to stratify prostate cancer patients for optimal treatment. The aims of…”
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Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer by Bruun, Jarle, Kolberg, Matthias, Ahlquist, Terje C, Røyrvik, Ellen C, Nome, Torfinn, Leithe, Edward, Lind, Guro E, Merok, Marianne A, Rognum, Torleiv O, Bjørkøy, Geir, Johansen, Terje, Lindblom, Annika, Sun, Xiao-Feng, Svindland, Aud, Liestøl, Knut, Nesbakken, Arild, Skotheim, Rolf I, Lothe, Ragnhild A

“…Colorectal cancer has high incidence and mortality worldwide. Patients with microsatellite instable (MSI) tumors have significantly better prognosis than…”
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Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development by SKOTHEIM, Rolf I, LIND, Guro E, LOTHE, Ragnhild A, MONNI, Outi, NESLAND, Jahn M, ABELER, Vera M, FOSSA, Sophie D, DUALE, Nur, BRUNBORG, Gunnar, KALLIONIEMI, Olli, ANDREWS, Peter W

“…Embryonal carcinoma is a histologic subgroup of testicular germ cell tumors (TGCTs), and its cells may follow differentiation lineages in a manner similar to…”
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New insights into testicular germ cell tumorigenesis from gene expression profiling by SKOTHEIM, Rolf I, MONNI, Outi, MOUSSES, Spyro, FOSSA, Sophie D, KALLIONIEMI, Olli-P, LOTHE, Ragnhild A, KALLIONIEMI, Anne

“…We have shown recently that about half of the human TGCTs(3) reveal DNA copy number increases affecting two distinct regions on chromosome arm 17q. To identify…”
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PO-505 Prognostic impact of KRAS splicing in microsatellite stable colorectal cancer by Eilertsen, IA, Sveen, A, Hektoen, M, Strømme, JM, Johannessen, B, Skotheim, RI, Nesbakken, A, Lothe, RA

“…IntroductionMutations in the KRAS oncogene represent one of the most common genetic alterations in colorectal cancer (CRC). KRAS is expressed as two transcript…”
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PO-311 Multifocality complicates molecular classification of primary prostate cancer by Carm, K, Zhao, S, Bakken, AC, Johannessen, B, Hoff, AM, Axcrona, U, Axcrona, K, Lothe, RA, Skotheim, RI, Løvf, M

“…IntroductionProstate cancer is the most common cancer type among men in the Western developed world. The majority of cases are multifocal, with several…”
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Topoisomerase-IIα Is Upregulated in Malignant Peripheral Nerve Sheath Tumors and Associated With Clinical Outcome by SKOTHEIM, Rolf I, KALLIONIEMI, Anne, SMELAND, Sigbjørn, KALLIONIEMI, Olli-P, LOTHE, Ragnhild A, BJERKHAGEN, Bodil, MERTENS, Fredrik, BREKKE, Helge R, MONNI, Outi, MOUSSES, Spyro, MANDAHL, Nils, SOETER, Gunnar, NESLAND, Jahn M

“…To identify target genes of clinical significance for patients with malignant peripheral-nerve sheath tumor (MPNST), an aggressive cancer for which no…”
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Identification of Two Molecular Groups of Seminomas by Using Expression and Tissue Microarrays by HOFER, Matthias D, BROWNE, Tara J, LE HE, SKOTHEIM, Rolf I, LOTHE, Ragnhild A, RUBIN, Mark A

“…Highly effective tailored clinical management of testicular germ cell tumors is based on the identification of two major histologic subtypes: seminomatous and…”
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Genome profiles of familial/bilateral and sporadic testicular germ cell tumors by Kraggerud, Sigrid Marie, Skotheim, Rolf I., Szymanska, Jadwiga, Eknæs, Mette, Fosså, Sophie D., Stenwig, Anna E., Peltomäki, Päivi, Lothe, Ragnhild A.

“…In order to investigate the genetics of testicular germ cell tumors (TGCTs), we examined 33 TGCTs, including 15 familial/bilateral and 18 sporadic tumors,…”
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The testicular germ cell tumour genome by SKOTHEIM, ROLF I., LOTHE, RAGNHILD A.

“…Human testicular germ cell tumour (TGCT) of adolescents and young adults develop from precursor lesions called carcinoma in situ (CIS), which is believed to…”
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Candidate Genes for Testicular Cancer Evaluated by In Situ Protein Expression Analyses on Tissue Microarrays by Skotheim, Rolf I., Abeler, Vera M., Nesland, Jahn M., Fosså, Sophie D., Holm, Ruth, Wagner, Urs, Flørenes, Vivi Ann, Aass, Nina, Kallioniemi, Olli P., Lothe, Ragnhild A.

“…By the use of high-throughput molecular technologies, the number of genes and proteins potentially relevant to testicular germ cell tumor (TGCT) and other…”
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Microinvasive germ cell tumor of the testis by VON EYBEN, Finn Edler, JACOBSEN, Grete Krag, SKOTHEIM, Rolf Inge

“…Microinvasive germ cell tumor (MGCT) consists of a limited number of malignant germ cells in the intertubular tissue of the testis. The cells have large…”
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NKX3.1 Expression Is Lost in Testicular Germ Cell Tumors by Skotheim, Rolf I., Korkmaz, Kemal S., Klokk, Tove I., Abeler, Vera M., Korkmaz, Ceren G., Nesland, Jahn M., Fosså, Sophie D., Lothe, Ragnhild A., Saatcioglu, Fahri

“…NKX3.1 is a homeobox gene which exhibits prostate and testis specific expression. Loss of NKX3.1 expression has been implicated in prostate development and…”
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Familial/Bilateral and Sporadic Testicular Germ Cell Tumors Show Frequent Genetic Changes at Loci with Suggestive Linkage Evidence by Skotheim, Rolf I., Kraggerud, Sigrid M., Fosså, Sophie D., Stenwig, Anna E., Gedde-Dahl, Tobias, Danielsen, Håvard E., Jakobsen, Kjetill S., Lothe, Ragnhild A.

“…Testicular germ cell tumor (TGCT) is the most common tumor type among adolescent and young adult males. Familial clustering and bilateral disease are…”
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Evaluation of loss of heterozygosity/allelic imbalance scoring in tumor DNA by Skotheim, Rolf I, Diep, Chieu B, Kraggerud, Sigrid M, Jakobsen, Kjetill S, Lothe, Ragnhild A

“…Loss of heterozygosity and allelic imbalance in tumors are usually detected by either radioactive labeling of PCR products with subsequent scoring of…”
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Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors by Kraggerud, Sigrid M, Lee, Maxwell P, Skotheim, Rolf I, Stenwig, Anna E, Fosså, Sophie D, Feinberg, Andrew P, Lothe, Ragnhild A

“…Allelic imbalance (AI) at loci on chromosome 11 has been shown in several types of human solid tumors, including testicular germ cell tumors (TGCTs). In this…”
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