Search Results - "Skorska, Anna"
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Combined Gemcitabine and Immune-Checkpoint Inhibition Conquers Anti-PD-L1 Resistance in Low-Immunogenic Mismatch Repair-Deficient Tumors
Published in International journal of molecular sciences (01-06-2021)“…Tumors arising in the context of Lynch Syndrome or constitutional mismatch repair deficiency are hypermutated and have a good response towards…”
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Quantitative Evaluation of the Sarcomere Network of Human hiPSC-Derived Cardiomyocytes Using Single-Molecule Localization Microscopy
Published in International journal of molecular sciences (17-04-2020)“…The maturation of iPSC-derived cardiomyocytes is still a critical point for their application in cardiovascular research as well as for their clinical use…”
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3
Monitoring the maturation of the sarcomere network: a super-resolution microscopy-based approach
Published in Cellular and molecular life sciences : CMLS (01-03-2022)“…The in vitro generation of human cardiomyocytes derived from induced pluripotent stem cells (iPSC) is of great importance for cardiac disease modeling,…”
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The Effects of Hypoxic Preconditioned Murine Mesenchymal Stem Cells on Post-Infarct Arrhythmias in the Mouse Model
Published in International journal of molecular sciences (09-08-2022)“…Ventricular arrhythmias associated with myocardial infarction (MI) have a significant impact on mortality in patients following heart attack. Therefore,…”
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Innovative strategy for microRNA delivery in human mesenchymal stem cells via magnetic nanoparticles
Published in International journal of molecular sciences (23-05-2013)“…Bone marrow derived human mesenchymal stem cells (hMSCs) show promising potential in regeneration of defective tissue. Recently, gene silencing strategies…”
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CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation
Published in Genome medicine (10-08-2023)“…The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation…”
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BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice
Published in Cell death & disease (15-08-2023)“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
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Angiogenic Potential of Bone Marrow Derived CD133 + and CD271 + Intramyocardial Stem Cell Trans- Plantation Post MI
Published in Cells (Basel, Switzerland) (27-12-2019)“…Bone marrow (BM)-derived stem cells with their various functions and characteristics have become a well-recognized source for the cell-based therapies…”
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Dose-Independent Therapeutic Benefit of Bone Marrow Stem Cell Transplantation after MI in Mice
Published in Biomedicines (11-06-2020)“…Several cell populations derived from bone marrow (BM) have been shown to possess cardiac regenerative potential. Among these are freshly isolated CD133+…”
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10
Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart
Published in Disease models & mechanisms (01-06-2018)“…Ischemic heart failure is the leading cause of mortality worldwide. An early boost of intracardiac regenerative key mechanisms and angiogenetic niche signaling…”
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11
CD271 + Human Mesenchymal Stem Cells Show Antiarrhythmic Effects in a Novel Murine Infarction Model
Published in Cells (Basel, Switzerland) (20-11-2019)“…Ventricular arrhythmias (VA) are a common cause of sudden death after myocardial infarction (MI). Therefore, developing new therapeutic methods for the…”
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12
Cardiac Mesenchymal Stem Cells Proliferate Early in the Ischemic Heart
Published in European surgical research (01-01-2017)“…Cardiac mesenchymal stem cells (MSCs) could stimulate cell-specific regenerative mechanisms after myocardial infarction (MI) depending on spatial origin,…”
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13
Cardiomyocyte Transplantation after Myocardial Infarction Alters the Immune Response in the Heart
Published in Cells (Basel, Switzerland) (03-08-2020)“…We investigated the influence of syngeneic cardiomyocyte transplantation after myocardial infarction (MI) on the immune response and cardiac function. Methods…”
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14
Continuous Electrical Stimulation Affects Initial Growth and Proliferation of Adipose-Derived Stem Cells
Published in Biomedicines (08-11-2020)“…The aim of the study was to establish electrical stimulation parameters in order to improve cell growth and viability of human adipose-derived stem cells…”
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15
Defining Optimized Properties of Modified mRNA to Enhance Virus- and DNA- Independent Protein Expression in Adult Stem Cells and Fibroblasts
Published in Cellular physiology and biochemistry (01-01-2015)“…Background: By far, most strategies for cell reprogramming and gene therapy are based on the introduction of DNA after viral delivery. To avoid the high risks…”
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Exploiting AT2R to Improve CD117 Stem Cell Function In Vitro and In Vivo - Perspectives for Cardiac Stem Cell Therapy
Published in Cellular physiology and biochemistry (01-01-2015)“…Background/Aims: CD117 + stem cell (SC) based therapy is considered an alternative therapeutic option for terminal heart disease. However, controversies exist…”
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17
Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105^+ hMSCs
Published in Stem Cells International (01-01-2014)“…Genetic modifications of bone marrow derived human mesenchymal stem cells (hMSCs) using microRNAs (miRs) may be used to improve their therapeutic potential and…”
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Cardiac Function Improvement and Bone Marrow Response
Published in EBioMedicine (01-08-2017)“…The phase III clinical trial PERFECT was designed to assess clinical safety and efficacy of intramyocardial CD133+ bone marrow stem cell treatment combined…”
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Selective Migration of Subpopulations of Bone Marrow Cells along an SDF-1α and ATP Gradient
Published in Bone Marrow Research (01-01-2014)“…Both stem cell chemokine stromal cell-derived factor-1α (SDF-1α) and extracellular nucleotides such as adenosine triphosphate (ATP) are increased in ischemic…”
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The phenomenon of social exclusion in European Union Countries in relation to Europe 2020 Strategy
Published in Viešoji politika ir administravimas (2017)“…Europe 2020- A strategy for smart, sustainable and inclusive growth” is a long term programme of socioeconomic development of European Union for 2010 – 2020…”
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