Search Results - "Skogastierna, C"

A supraphysiological dose of testosterone induces nitric oxide production and oxidative stress by Skogastierna, Cristine, Hotzen, Maja, Rane, Anders, Ekström, Lena

“…Background Accumulating evidence indicates that abuse of anabolic androgenic steroids may cause cardiovascular adverse side-effects, including endothelial…”
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Functional ATP-binding cassette drug efflux transporters in isolated human and rat hepatocytes significantly affect assessment of drug disposition by Lundquist, Patrik, Englund, Gunilla, Skogastierna, Cristine, Lööf, Johan, Johansson, Jenny, Hoogstraate, Janet, Afzelius, Lovisa, Andersson, Tommy B

“…Freshly isolated hepatocytes are considered the gold standard for in vitro studies of hepatic drug disposition. To ensure a reliable supply of cells,…”
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Cytochrome p450 inhibitory properties of common efflux transporter inhibitors by Englund, Gunilla, Lundquist, Patrik, Skogastierna, Cristine, Johansson, Jenny, Hoogstraate, Janet, Afzelius, Lovisa, Andersson, Tommy B, Projean, Denis

“…Drug transporter inhibitors are important tools to elucidate the contribution of transporters to drug disposition both in vitro and in vivo. These inhibitors…”
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Statins inhibit expression of Thioredoxin reductase 1 in rat and human liver and reduce tumour development by Skogastierna, Cristine, Johansson, Maria, Parini, Paolo, Eriksson, Mats, Eriksson, Lennart C., Ekström, Lena, Björkhem-Bergman, Linda

“…► Statins inhibits expression of Thioredoxin reductase 1 in rat and human liver tissue. ► Statin-mediated inhibition of Thioredoxin reductases may explain…”
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Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA reductase by Gårevik, Nina, Skogastierna, Cristine, Rane, Anders, Ekström, Lena

“…Cholesterol is mainly synthesised in liver and the rate-limiting step is the reduction of 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) to mevalonate, a…”
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Rapid Single-Nucleotide Polymorphism Detection of Cytochrome P450 (CYP2C9) and Vitamin K Epoxide Reductase (VKORC1) Genes for the Warfarin Dose Adjustment by the SMart-Amplification Process Version 2 by Aomori, Tohru, Yamamoto, Koujirou, Oguchi-Katayama, Atsuko, Kawai, Yuki, Ishidao, Takefumi, Mitani, Yasumasa, Kogo, Yasushi, Lezhava, Alexander, Fujita, Yukiyoshi, Obayashi, Kyoko, Nakamura, Katsunori, Kohnke, Hugo, Wadelius, Mia, Ekstrom, Lena, Skogastierna, Cristine, Rane, Anders, Kurabayashi, Masahiko, Murakami, Masami, Cizdziel, Paul E, Hayashizaki, Yoshihide, Horiuchi, Ryuya

“…Polymorphisms of the CYP2C9 (cytochrome P450, family 2, subfamily C, polypeptide 9) gene (CYP2C9*2, CYP2C9*3) and the VKORC1 (vitamin K epoxide reductase…”
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Regulation and expression of human CYP7B1 in prostate: Overexpression of CYP7B1 during progression of prostatic adenocarcinoma by Olsson, Mats, Gustafsson, Ove, Skogastierna, Cristine, Tolf, Anna, Rietz, Barbara Du, Morfin, Robert, Rane, Anders, Ekström, Lena

“…BACKGROUND Cytochrome P450 (CYP) 7B1 is involved in many metabolic processes including androgen metabolism. Cytochrome P450 (CYP) 7B1 is expressed within the…”
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Regulation and expression of human CYP7131 in prostate:: Overexpression of CYP7131 during progression of prostatic adenocarcinoma by Olsson, M, Gustafsson, O, Skogastierna, C, Tolf, A, Du, Rietz B, Morfin, R, Rane, A, Ekstrom, L

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Influence of Simvastatin on the Thromboxane and Prostacyclin Pathways, In Vitro and In Vivo by Skogastierna, Cristine, Björkhem-Bergman, Linda, Bergman, Peter, Eliasson, Erik, Rane, Anders, Ekström, Lena

“…3-hydroxyl-3-methylglutaryl coenzyme A reductase inhibitors (statins) are believed to exert beneficial effects against cardiovascular disease beyond correction…”
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Beneficial vasoactive endothelial effects of fluvastatin: focus on prostacyclin and nitric oxide by Skogastierna, Cristine, Luksha, Leonid, Kublickiene, Karolina, Eliasson, Erik, Rane, Anders, Ekström, Lena

“…Statins are believed to exert beneficial effects against cardiovascular disease beyond correction of dyslipidemia. There are however still very sparse data on…”
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Daunorubicin metabolism in leukemic cells isolated from patients with acute myeloid leukemia by Bogason, Alex, Masquelier, Michéle, Lafolie, Pierre, Skogastierna, Cristine, Paul, Christer, Gruber, Astrid, Vitols, Sigurd

“…Anthracyclines like daunorubicin (DNR) are important drugs in the treatment of acute myeloid leukaemia (AML). In vitro studies have shown that cellular…”
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THE PLEIOTROPIC EFFECTS OF FLUVASTATIN IN HUMAN VASCULAR ENDOTHELIUM by Skogastierna, C, Luksha, L, Kublickiene, K, Eliasson, E, Rane, A, Ekstrom, L

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