Search Results - "Skoblov, M. Yu"

Isolation and Characterization of Human Myoblast Culture In Vitro for Technologies of Cell and Gene Therapy of Skeletal Muscle Pathologies by Tabakov, V. Yu, Zinov’eva, O. E., Voskresenskaya, O. N., Skoblov, M. Yu

“…We analyzed cultures of 5 independent myoblast lines from human skeletal muscles. It was shown that the content of desmin-positive cells in cultures at early…”
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The novel synonymous variant in LIPA gene affects splicing and causes lysosomal acid lipase deficiency by Bychkov, I.O., Kamenets, E.A., Filatova, A.Yu, Skoblov, M.Yu, Mikhaylova, S.V., Strokova, T.V., Gundobina, O.S., Zakharova, E.Yu

“…Lysosomal acid lipase deficiency (LALD; MIM#278000) is a continuum of autosomal recessive diseases caused by defects in the gene LIPA and historically divided…”
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Antisense regulation of human gene MAP3K13: True phenomenon or artifact? by Marakhonov, A. V., Baranova, A. V., Skoblov, M. Yu

“…Antisense regulation of gene expression is a widespread but poorly understood mechanism of gene expression regulation. The potential role of antisense…”
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The genome nucleotide sequence of herpes simplex virus 1 strain L2 by Skoblov, M. Yu, Lavrov, A. V., Bragin, A. G., Zubtsov, D. A., Andronova, V. L., Galegov, G. A., Skoblov, Yu. S.

“…The genome nucleotide sequence of the reference strain of herpes simplex virus type 1 was obtained using the technique of full size sequencing. For the virus…”
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Prospects of antisense therapy technologies by Skoblov, M. Yu

“…Three variants of antisense technologies are presently known: antisense oligonucleotides, RNA interference, and ribozymes. In spite of the difference in the…”
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RANDTRAN: Random transcriptome sequence generator that accounts for partition specific features in eukaryotic mRNA datasets by Borzov, E. A., Marakhonov, A. V., Ivanov, M. V., Drozdova, P. B., Baranova, A. V., Skoblov, M. Yu

“…The generation of true random and pseudorandom control sequences is an important problem of computational biology. Available random sequence generators differ…”
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Therapeutic siRNAs and nonviral systems for their delivery by Glebova, K. V., Marakhonov, A. V., Baranova, A. V., Skoblov, M. Yu

“…Gene-directed therapy with small interfering RNA (siRNA) has a tremendous potential and will undoubtedly occupy one of the leading positions among other…”
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Nonviral delivery systems for small interfering RNAs by Glebova, K. V., Marakhonov, A. V., Baranova, A. V., Skoblov, M. Yu

“…RNA interference is now considered to be the most powerful and promising tool for gene-targeted therapy. Several problems are still to be solved for its…”
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Molecular genetic analysis of DNA polymerase and thymidine kinase genes of a HSV-1 population using an MPS technology by Gus’kova, A. A., Skoblov, M. Yu, Lavrov, A. V., Zubtsov, D. A., Andronova, V. L., Goldshtein, D. V., Galegov, G. A., Skoblov, Yu. S.

“…Real-time PCR was used to determine the ratio of viral and host DNA in lysates of Vero cells infected with HSV-1 strain L2. The number of virus copies reached…”
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Enzymatic activity of thymidine kinases of a herpes simplex virus strains resistant to acyclovir H-phosphonates by Gus’kova, A. A., Skoblov, M. Yu, Andronova, V. L., Galegov, G. A., Kochetkov, S. N., Skoblov, Yu. S.

“…Some cloned laboratory mutant strains of herpes simplex virus type I resistant to acyclovir H-phosphonate were studied. As was shown for all the clones, the…”
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Mutations in the DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs by Korovina, A. N, Gus'kova, A. A, Skoblov, M. Yu, Andronova, V. L, Galegov, G. A, Kochetkov, S. N, Kukhanova, M. K, Skoblov, Yu. S

“…Primary structures of DNA polymerase (ul30) and thymidine kinase (ul23) genes from several herpes simplex virus type 1 (HSV-1) clinical isolates di ffering in…”
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DNA assay for recombinant pharmaceutical substances using the real-time PCR technique by Skoblov, M. Yu, Shibanova, E. D, Kovaleva, E. V, Bairamashvilli, D. I, Skoblov, Yu. S, Miroshnikov, A. I

“…A real-time PCR procedure is proposed for assaying E. coli residual DNA in the pharmaceutical substance of human recombinant insulin. For the quantitative…”
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Developmental and Epileptic Encephalopathy Produced by the ATP1A2 Mutation by Rudenskaya, G. E., Guseva, D. M., Shatokhina, O. L., Kadnikova, V. A., Filatova, A. Yu, Skoblov, M. Yu, Ryzhkova, O. P.

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Cloning and expression of the IGA-specific endopeptidase genes from Neisseria meningitides by Khomenkov, V. G., Kazeeva, T. N., Shevelev, B. I., Bargrasser, V. P., Skoblov, M. Yu, Shevelev, A. B.

“…IgA1-specific proteinases (Igase) are known as a pivotal pathogenicity factor in meningococcus (Neisseria meningitides) and in some related bacteria. These…”
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Developmental and epileptic encephalopathy produced by the ATP1A2 mutation by Rudenskaya, G E, Guseva, D M, Shatokhina, O L, Kadnikova, V A, Filatova, A Yu, Skoblov, M Yu, Ryzhkova, O P

“…A case of DEE98, a rare developmental and epileptic encephalopathy related to previously reported the missense mutation p.Arg908Gln in the gene, is described…”
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Sodium Channelopathies: From Molecular Physiology towards Medical Genetics by Marakhonov, A. V., Varenikov, G. G., Skoblov, M. Yu

“…Voltage-gated sodium channels are heteromeric transmembrane proteins involved in the conduction of sodium ion currents in response to membrane depolarization…”
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Molecular genetic analysis of thymidine kinase of the herpes simplex virus type 1 by Guskova, A A, Zagurny, A V, Skoblov, MYu, Baranova, A V, Andronova, V L, Yankovsky, N K, Galegov, G A, Skoblov, YuS

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The Mechanisms of Transgenerational Inheritance and Their Potential Contribution to Human Phenotypes by Skoblov, M Yu, Scobeyeva, V A, Baranova, A V

“…As of today, classical genetics has already completed the majority of groundwork to describe the laws of inheritance, identify the causes of many human…”
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Clinical and genetic characteristics and diagnostic features of Landouzy–Dejerine facioscapulohumeral muscular dystrophy by Zernov, N. V., Marakhonov, A. V., Vyakhireva, J. V., Guskova, A. A., Dadali, E. L., Skoblov, M. Yu

“…Landouzy–Dejerine facioscapulohumeral muscular dystrophy (FSHD) is one of the most common hereditary myodystrophies. A study of the genetic nature of the…”
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mechanisms of transgenerational inheritance and their potential contribution to human phenotypes by Skoblov, M. Yu, Scobeyeva, V. A., Baranova, A. V.

“…As of today, classical genetics has already completed the majority of groundwork to describe the laws of inheritance, identify the causes of many human…”
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