Search Results - "Skjoedt, Karsten"
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Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity
Published in Nature communications (14-07-2022)“…Th17 cells are key drivers of autoimmune disease. However, the signaling pathways regulating Th17 polarization are poorly understood. Hedgehog signaling…”
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Cellular and humoral factors involved in the response of rainbow trout gills to Ichthyophthirius multifiliis infections: Molecular and immunohistochemical studies
Published in Fish & shellfish immunology (01-03-2011)“…The parasitic ciliate Ichthyophthirius multifiliis infecting skin, fins and gills of fish induces a protective immune response in rainbow trout ( Oncorhynchus…”
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Calcium-sensitive immunoaffinity chromatography: Gentle and highly specific retrieval of a scarce plasma antigen, collectin-LK (CL-LK)
Published in Journal of immunological methods (01-11-2014)“…Immunoaffinity chromatography is a powerful fractionation technique that has become indispensable for protein purification and characterization. However, it is…”
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CL-L1 and CL-K1 Exhibit Widespread Tissue Distribution With High and Co-Localized Expression in Secretory Epithelia and Mucosa
Published in Frontiers in immunology (31-07-2018)“…Collectin liver 1 (CL-L1, alias collectin 10) and collectin kidney 1 (CL-K1, alias collectin 11) are oligomeric pattern recognition molecules associated with…”
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Sodium Polyanethole Sulfonate as an Inhibitor of Activation of Complement Function in Blood Culture Systems
Published in Journal of Clinical Microbiology (01-03-2010)“…Sodium polyanethole sulfonate (SPS; trade name, Liquoid) is a constituent in culture media used to grow bacteria from blood samples from patients suspected of…”
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Complement defects in patients with chronic rhinosinusitis
Published in PloS one (07-11-2012)“…The complement system is an important part of our immune system, and complement defects lead generally to increased susceptibility to infections and autoimmune…”
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OSCAR is a receptor for surfactant protein D that activates TNF-α release from human CCR2+ inflammatory monocytes
Published in The Journal of immunology (1950) (01-04-2015)“…Surfactant protein D (SP-D) is critical for maintenance of lung homeostasis and provides a first line of defense to pathogens at mucosal surfaces…”
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Collectin 11 (CL-11, CL-K1) is a MASP-1/3-associated plasma collectin with microbial-binding activity
Published in The Journal of immunology (1950) (15-11-2010)“…Collectins play important roles in the innate immune defense against microorganisms. Recently, a new collectin, collectin 11 (CL-11 or CL-K1), was identified…”
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CD8+ T cells complement antibodies in protecting against yellow fever virus
Published in The Journal of immunology (1950) (01-02-2015)“…The attenuated yellow fever (YF) vaccine (YF-17D) was developed in the 1930s, yet little is known about the protective mechanisms underlying its efficiency. In…”
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A novel antihuman C3d monoclonal antibody with specificity to the C3d complement split product
Published in Journal of immunological methods (01-05-2017)“…The complement component C3 and the cleavage products of C3b/iC3b, C3c and C3d are used as biomarkers in clinical diagnostics. Currently, no specific…”
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Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors
Published in The Journal of biological chemistry (04-01-2019)“…Matriptase is a member of the type-II transmembrane serine protease (TTSP) family and plays a crucial role in the development and maintenance of epithelial…”
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The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema
Published in The Journal of immunology (1950) (15-10-2015)“…C1 inhibitor (C1-INH) is known to form complexes with the lectin complement pathway serine proteases MASP-1 and MASP-2. Deficiency of C1-INH is associated with…”
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CL-11 in systemic inflammatory response syndrome
Published in Molecular immunology (01-09-2017)Get full text
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Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. [Erratum: 2005 Feb. 17, v. 433, no. 7027, p. 777.]
Published in Nature (09-12-2004)“…We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first…”
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Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants
Published in Traffic (Copenhagen, Denmark) (01-08-2016)“…Krabbe disease is a devastating neurodegenerative disorder caused by defects in the lysosomal hydrolase galactocerebrosidase (GALC). Over 100 different…”
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TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils
Published in The Journal of immunology (1950) (01-10-2015)“…We identified a novel, evolutionarily conserved receptor encoded within the human leukocyte receptor complex and syntenic region of mouse chromosome 7, named T…”
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Fast form alpha-2-macroglobulin - A marker for protease activation in plasma exposed to artificial surfaces
Published in Clinical biochemistry (01-12-2017)“…Investigation of the blood compatibility requires a number of sensitive assays to quantify the activation of the blood protein cascades and cells induced by…”
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