Search Results - "Skinner, O"

Measuring mRNA copy number in individual Escherichia coli cells using single-molecule fluorescent in situ hybridization by Skinner, Samuel O, Sepúlveda, Leonardo A, Xu, Heng, Golding, Ido

“…We present a protocol for measuring the absolute number of mRNA molecules from a gene of interest in individual, chemically fixed Escherichia coli cells. A set…”
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Decision Making at a Subcellular Level Determines the Outcome of Bacteriophage Infection by Zeng, Lanying, Skinner, Samuel O., Zong, Chenghang, Sippy, Jean, Feiss, Michael, Golding, Ido

“…When the process of cell-fate determination is examined at single-cell resolution, it is often observed that individual cells undergo different fates even when…”
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Single-cell analysis of transcription kinetics across the cell cycle by Skinner, Samuel O, Xu, Heng, Nagarkar-Jaiswal, Sonal, Freire, Pablo R, Zwaka, Thomas P, Golding, Ido

“…Transcription is a highly stochastic process. To infer transcription kinetics for a gene-of-interest, researchers commonly compare the distribution of mRNA…”
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Computed tomography of a spontaneous subserosal duodenal haematoma in a cavalier king Charles spaniel by Schaul, K. R., Karnia, J. J., Skinner, O. T.

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Radiographs are of limited use and low cost-effectiveness when combined with ultrasound for abdominal restaging in dogs with solid, soft tissue tumours by Bevelock, T J, Skinner, O T, Baumgardner, R M, Dean, L, Matheson, J S, Mickelson, M A, Donnelly, L L, Hutcheson, K D

“…The purposes of this study were to assess the frequency of detection of clinically relevant findings by abdominal radiographs and abdominal ultrasound during…”
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Diagnostic accuracy of contrast‐enhanced computed tomography for assessment of mandibular and medial retropharyngeal lymph node metastasis in dogs with oral and nasal cancer by Skinner, O. T., Boston, S. E., Giglio, R. F., Whitley, E. M., Colee, J. C., Porter, E. G.

“…The diagnostic accuracy of contrast‐enhanced CT for detection of cervical lymph node metastasis in dogs is unknown. The purpose of this retrospective,…”
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Comparison of methods to determine primary tumour size in canine apocrine gland anal sac adenocarcinoma by Schlag, A. N., Johnson, T., Vinayak, A., Kuvaldina, A., Skinner, O. T., Wustefeld‐Janssens, B. G.

“…Objectives To assess agreement between measurement of primary apocrine gland anal sac adenocarcinoma tumours using digital palpation, CT and formalin‐fixed…”
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Single-Virus Tracking Reveals a Spatial Receptor-Dependent Search Mechanism by Rothenberg, Eli, Sepúlveda, Leonardo A., Skinner, Samuel O., Zeng, Lanying, Selvin, Paul R., Golding, Ido

“…Viral infection begins with the binding of a virus to a specific target on the surface of the host cell, followed by viral genome delivery into the host and a…”
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Lysogen stability is determined by the frequency of activity bursts from the fate-determining gene by Zong, Chenghang, Golding, Ido, So, Lok-hang, Sepúlveda, Leonardo A, Skinner, Samuel O

“…The ability of living cells to maintain an inheritable memory of their gene‐expression state is key to cellular differentiation. Bacterial lysogeny serves as a…”
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Clinical features and outcome of functional thyroid tumours in 70 dogs by Scharf, V. F., Oblak, M. L., Hoffman, K., Skinner, O. T., Neal, K. M., Cocca, C. J., Duffy, D. J., Wallace, M. L.

“…Objective To describe the clinical features and outcome of functional thyroid tumours in dogs. Materials and Methods Retrospective multi‐institutional study of…”
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In vivo femorotibial subluxation during weight-bearing and clinical outcome following tibial tuberosity advancement for cranial cruciate ligament insufficiency in dogs by Skinner, O.T., Kim, S.E., Lewis, D.D., Pozzi, A.

“…Ex vivo studies have been used extensively to investigate the mechanisms of tibial osteotomies but few have explored femorotibial alignment in vivo. The aim of…”
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Grain-boundary fluctuations in two-dimensional colloidal crystals by Skinner, Thomas O E, Aarts, Dirk G A L, Dullens, Roel P A

“…We study grain-boundary fluctuations in two-dimensional colloidal crystals in real space and time using video microscopy. The experimentally obtained static…”
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IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function by Speake, Cate, Habib, Tania, Lambert, Katharina, Hundhausen, Christian, Lord, Sandra, Dufort, Matthew J, Skinner, Samuel O, Hu, Alex, Kinsman, MacKenzie, Jones, Britta E, Maerz, Megan D, Tatum, Megan, Hocking, Anne M, Nepom, Gerald T, Greenbaum, Carla J, Buckner, Jane H

“…Therapeutics that inhibit IL-6 at different points in its signaling pathway are in clinical use, yet whether the immunological effects of these interventions…”
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Stochastic Kinetics of Nascent RNA by Xu, Heng, Skinner, Samuel O, Sokac, Anna Marie, Golding, Ido

“…The stochastic kinetics of transcription is typically inferred from the distribution of RNA numbers in individual cells. However, cellular RNA reflects…”
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Ghrelin Can Bind to a Species of High Density Lipoprotein Associated with Paraoxonase by Beaumont, Nicholas J, Skinner, Vernon O, Tan, Tricia M-M, Ramesh, Bala S, Byrne, Dominic J, MacColl, Gavin S, Keen, Jeff N, Bouloux, Pierre M, Mikhailidis, Dimitri P, Bruckdorfer, K Richard, Vanderpump, Mark P, Srai, Kaila S

“…Ghrelin is a 28-residue peptide hormone that is principally released from the stomach during fasting and prior to eating. Two forms are present in human…”
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Systemic amitriptyline administration does not prevent the increased thermal response induced by paradoxical sleep deprivation by Damasceno, Fabio, Skinner, Gabriela O., Gomes, Aline, Araújo, Paulo C., de Almeida, Olga M.M.S.

“…Sleep deprivation has been associated with hyperalgesia in humans and in animal models. The tricyclic antidepressant amitriptyline is used as an analgesic drug…”
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Computed tomographic evaluation of elbow congruity during arthroscopy in a canine cadaveric model by Skinner, O T, Warren-Smith, C M R, Burton, N J, Parsons, K J

“…To assess the effect of arthroscope insertion, using a carbon-fibre rod model, on humero-radial, humero-ulnar and radio-ulnar congruity, as assessed by…”
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Localization dynamics of fluids in random confinement by Skinner, Thomas O E, Schnyder, Simon K, Aarts, Dirk G A L, Horbach, Jürgen, Dullens, Roel P A

“…The dynamics of two-dimensional fluids confined within a random matrix of obstacles is investigated using both colloidal model experiments and molecular…”
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Thiobarbituric acid reactive substances in the cerebrospinal fluid in schizophrenia by Skinner, Andrew O., Mahadik, Sahebarao P., Garver, David L.

“…Increased levels of lipid peroxidation products (thiobarbituric acid reactive substances [TBARS]) are reported in plasma/serum from patients with…”
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Components of feed efficiency in broiler breeding stock: energetics, performance, carcass composition, metabolism, and body temperature by Skinner-Noble, D O, Teeter, R G

“…Two experiments were conducted to identify factors influencing feed conversion in broilers. The first experiment was conducted to develop a test for body…”
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