Search Results - "Skinner, Jarrod"
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MYL9 deficiency is neonatal lethal in mice due to abnormalities in the lung and the muscularis propria of the bladder and intestine
Published in PloS one (08-07-2022)“…Class II myosin complexes are responsible for muscle contraction as well as other non-sarcomeric contractile functions in cells. Myosin heavy chain molecules…”
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Expression of the miR‐17~92a cluster of microRNAs by regulatory T cells controls blood glucose homeostasis
Published in Immunology and cell biology (01-02-2022)“…Regulatory T cells (Tregs) are a specialized immune cell type that play important roles in regulating immune responses. However, those found in adipose tissue,…”
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A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity
Published in PloS one (29-07-2015)“…We identified Mrpl44 in a search for mammalian proteins that contain RNase III domains. This protein was previously found in association with the mitochondrial…”
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The miR-17 ∼ 92a cluster of microRNAs is required for the fitness of Foxp3+ regulatory T cells
Published in PloS one (11-02-2014)“…By genetic inactivation of key microRNA biogenesis enzymes, we and others have previously demonstrated the critical requirement of the microRNA pathway for the…”
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A Role for the Calcitonin Receptor to Limit Bone Loss During Lactation in Female Mice by Inhibiting Osteocytic Osteolysis
Published in Endocrinology (Philadelphia) (01-09-2015)“…During lactation, the large transfer of calcium from the mother to the milk is primarily sourced from the maternal skeleton. To determine whether the…”
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A comparison of alternative mRNA splicing in the CD4 and CD8 T cell lineages
Published in Molecular immunology (01-05-2021)“…•Integrating short and long RNA-seq data is effective for mapping and quantifying alternative mRNA splicing.•Short-read alone is ineffective for assembling…”
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Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential
Published in Frontiers in immunology (03-04-2023)“…The αβ and γδ T cell lineages both differentiate in the thymus from common uncommitted progenitors. The earliest stage of T cell development is known as CD4…”
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The role of microRNAs in lymphopoiesis
Published in International journal of hematology (01-09-2014)“…The immune system is composed of a diverse range of cell types, each with a distinct function. It can be broadly divided into the lymphoid (T, B, NK, etc.) and…”
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Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual
Published in Transgenic research (01-08-2012)“…Conditional gene inactivation using the Cre/loxP system has lead to significant advances in our understanding of the function of genes in a wide range of…”
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Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation
Published in American journal of physiology: endocrinology and metabolism (01-07-2011)“…The aim of this study is to determine if the Odc1 gene, which encodes ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis, is…”
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Muscle-specific androgen receptor deletion shows limited actions in myoblasts but not in myofibers in different muscles in vivo
Published in Journal of molecular endocrinology (01-08-2016)“…The aim of this study was to investigate the direct muscle cell-mediated actions of androgens by comparing two different mouse lines. The cre-loxP system was…”
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Identification of gene pathways altered by deletion of the androgen receptor specifically in mineralizing osteoblasts and osteocytes in mice
Published in Journal of molecular endocrinology (01-08-2012)“…Androgens play a key role in skeletal growth and maintenance in males and can mediate their actions, at least in part, via the androgen receptor (AR) in…”
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Spatio-temporal observations of temperature and wind velocity using drone-based acoustic atmospheric tomography
Published in The Journal of the Acoustical Society of America (01-03-2019)“…This paper reports on a sequence of trials in which the acoustic signature of a small remotely piloted vehicle (drone) has been used to obtain spatio-temporal…”
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The miR-17~92a Cluster of MicroRNAs Is Required for the Fitness of Foxp3.sup.+ Regulatory T Cells
Published in PloS one (11-02-2014)“…By genetic inactivation of key microRNA biogenesis enzymes, we and others have previously demonstrated the critical requirement of the microRNA pathway for the…”
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The role of the calcitonin receptor in protecting against induced hypercalcemia is mediated via its actions in osteoclasts to inhibit bone resorption
Published in Bone (New York, N.Y.) (01-02-2011)“…Abstract Despite the therapeutic value of calcitonin in treating bone disease, a biological role of endogenous calcitonin is controversial. Having previously…”
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The role of microRNAs in lymphopoiesis : Epigenetic regulation of lymphopoiesis
Published in International journal of hematology (2014)Get full text
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The miR-17 similar to 92a Cluster of MicroRNAs Is Required for the Fitness of Foxp3+ Regulatory T Cells: e88997
Published in PloS one (01-02-2014)“…By genetic inactivation of key microRNA biogenesis enzymes, we and others have previously demonstrated the critical requirement of the microRNA pathway for the…”
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