Search Results - "Skinner, Donal C."

Gonadotropin-Releasing Hormone in Third Ventricular Cerebrospinal Fluid: Endogenous Distribution and Exogenous Uptake by Caraty, Alain, Skinner, Donal C

“…GnRH is detectable in the cerebrospinal fluid (CSF), but its source remains unidentified. Previous studies have harvested CSF for GnRH analysis from the median…”
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Rethinking the stalk effect: A new hypothesis explaining suprasellar tumor-induced hyperprolactinemia by Skinner, Donal C

“…Summary The pars tuberalis is a distinct subdivision of the pituitary gland but its function remains poorly understood. Suprasellar tumors in this pars…”
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Maternal Undernutrition from Early- to Mid-Gestation Leads to Growth Retardation, Cardiac Ventricular Hypertrophy, and Increased Liver Weight in the Fetal Sheep by Vonnahme, Kimberly A, Hess, Bret W, Hansen, Thomas R, McCormick, Richard J, Rule, Daniel C, Moss, Gary E, Murdoch, William J, Nijland, Mark J, Skinner, Donal C, Nathanielsz, Peter W, Ford, Stephen P

“…Early gestation is critical for placentomal growth, differentiation, and vascularization, as well as fetal organogenesis. The fetal origins of adult disease…”
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Colocalization of Progesterone Receptors in Parvicellular Dynorphin Neurons of the Ovine Preoptic Area and Hypothalamus by Foradori, Chad D, Coolen, Lique M, Fitzgerald, Maureen E, Skinner, Donal C, Goodman, Robert L, Lehman, Michael N

“…Recent evidence suggests that the dynorphin-κ receptor opioid system acts to mediate the inhibitory effect of progesterone (P) on GnRH pulse frequency during…”
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Progesterone Priming Is Essential for the Full Expression of the Positive Feedback Effect of Estradiol in Inducing the Preovulatory Gonadotropin-Releasing Hormone Surge in the Ewe by Caraty, Alain, Skinner, Donal C

“…The luteal phase elevation in circulating progesterone (P) powerfully inhibits GnRH and, consequently, LH release, thereby preventing premature preovulatory LH…”
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Wired on steroids: sexual differentiation of the brain and its role in the expression of sexual partner preferences by Alexander, Brenda M, Skinner, Donal C, Roselli, Charles E

“…The preference to seek out a sexual partner of the opposite sex is robust and ensures reproduction and survival of the species. Development of female-directed…”
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Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS by Cardoso, Rodolfo C, Burns, Ashleigh, Moeller, Jacob, Skinner, Donal C, Padmanabhan, Vasantha

“…Prenatal testosterone (T) treatment recapitulates the reproductive and metabolic phenotypes of polycystic ovary syndrome in female sheep. At the neuroendocrine…”
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The Gonadotropin-Releasing Hormone Type I Receptor is Expressed in the Mouse Cerebellum by Albertson, Asher J., Talbott, Heather, Wang, Qi, Jensen, Dane, Skinner, Donal C.

“…Gonadotropin-releasing hormone (GnRH) is a decapeptide hypothalamic hormone that was named according to its first discovered function—at the head of the…”
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Influence of Estradiol on NADPH Diaphorase/Neuronal Nitric Oxide Synthase Activity and Colocalization with Progesterone or Type II Glucocorticoid Receptors in Ovine Hypothalamus by DUFOURNY, Laurence, SKINNER, Donal C

“…Nitric oxide (NO) has been shown to play an important role in both the neuroendocrine reproductive and stress axes, which are closely linked. Because…”
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Variable duration of reproductive suppression in male coyotes (Canis latrans) treated with a high dose of the gonadotrophin-releasing hormone agonist deslorelin by MacGregor, Marjorie J, Asa, Cheryl S, Skinner, Donal C

“…Effective and humane management strategies for coyotes (Canis latrans) remain elusive. We hypothesised that exposure to a high dose of a…”
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Does salt have a permissive role in the induction of puberty? by Pitynski, Dori, Flynn, Francis W, Skinner, Donal C

“…Abstract Puberty is starting earlier than ever before and there are serious physiological and sociological implications as a result of this development…”
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DOSE AND DURATIONAL EFFECTS OF THE GONADOTROPIN-RELEASING HORMONE AGONIST, DESLORELIN: THE MALE RAT (RATTUS NORVEGICUS) AS A MODEL by Edwards, Brian, Smith, Arik, Skinner, Donal C

“…Gonadotropin-releasing hormone (GnRH) agonists are routinely used to suppress the reproductive axis of many mammals, especially in zoos. Current treatments are…”
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CONTRACEPTION HAS GONE TO THE COYOTES (CANIS LATRANS) by MacGregor, Marjorie J, Perkins, Elsey G, Asa, Cheryl, Skinner, Donal C

“…Coyotes (Canis latrans) are predators of livestock. Current management programs, primarily lethal control, are ineffective for long-term management of…”
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Unmasking the Progesterone Receptor in the Preoptic Area and Hypothalamus of the Ewe: No Colocalization with Gonadotropin-Releasing Neurons by Skinner, Donal C, Caraty, Alain, Allingham, Ruth

“…Progesterone powerfully inhibits GnRH secretion in ewes, as in other species, but the neural mechanisms underlying this effect remain poorly understood…”
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Immunoreactive GnRH type I receptors in the mouse and sheep brain by Albertson, Asher J., Navratil, Amy, Mignot, Mallory, Dufourny, Laurence, Cherrington, Brian, Skinner, Donal C.

“…Gonadotropin Releasing Hormone-I (GnRH) has been implicated in an array of functions outside the neuroendocrine reproductive axis. Previous investigations have…”
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A novel animal model to study hot flashes: no effect of gonadotropin-releasing hormone by Albertson, Asher J., Skinner, Donal C.

“…OBJECTIVE:Menopausal hot flashes compromise the quality of life for most women. The physiological mechanisms underlying hot flashes remain poorly understood,…”
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Signaling Complexes Associated with the Type I Gonadotropin-Releasing Hormone (GnRH) Receptor: Colocalization of Extracellularly Regulated Kinase 2 and GnRH Receptor within Membrane Rafts by Bliss, Stuart P, Navratil, Amy M, Breed, Matthew, Skinner, Donal C, Clay, Colin M, Roberson, Mark S

“…Our previous work demonstrated that the type I GnRH receptor (GnRHR) resides exclusively and constitutively within membrane rafts in αT3-1 gonadotropes and…”
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Somatostatin-14 Neurons in the Ovine Hypothalamus: Colocalization with Estrogen Receptor α and Somatostatin-28(1–12) Immunoreactivity, and Activation in Response to Estradiol by Scanlan, Niamh, Dufourny, Laurence, Skinner, Donal C

“…Pituitary gland growth hormone (GH) secretion is influenced by two hypothalamic neuropeptides: growth hormone-releasing hormone (GHRH) and somatostatin. Recent…”
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Intra-pituitary administration revisited: Development of a novel in vivo approach to investigate the ovine hypophysis by Taylor, W. Andrew, Evans, Neil P., Hertz, Carole, Skinner, Donal C.

“…[Display omitted] ► Intra-pituitary infusion circumvents circulatory system. ► Technique permits administration of factors that could affect peripheral targets…”
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Duration and Amplitude of the Luteal Phase Progesterone Increment Times the Estradiol-Induced Luteinizing Hormone Surge in Ewes1 by Skinner, Donal C, Harris, Thomas G, Evans, Neil P

“…Progesterone (P) powerfully inhibits the neuroendocrine reproductive axis, but the mechanisms and site or sites of action of this steroid remain poorly…”
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