Search Results - "Skepper, J. N."

Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function by Ciechomska, I A, Goemans, G C, Skepper, J N, Tolkovsky, A M

“…The binding of Bcl-2 to Beclin-1 reduces Beclin-1's capacity to induce autophagy. Here, we have tested whether the interaction is reciprocated by loss of…”
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Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics by Porter, A.E., Patel, N., Skepper, J.N., Best, S.M., Bonfield, W.

“…The incorporation of silicate into hydroxyapatite (HA) has been shown to significantly increase the rate of bone apposition to HA bioceramic implants. However,…”
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Herpes Simplex Virus Nucleocapsids Mature to Progeny Virions by an Envelopment → Deenvelopment → Reenvelopment Pathway by Skepper, J N, Whiteley, A, Browne, H, Minson, A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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In vitro osteoblast response to ferritic stainless steel fiber networks for magneto-active layers on implants by Malheiro, V. N., Skepper, J. N., Brooks, R. A., Markaki, A. E.

“…The use of a porous coating on prosthetic components to encourage bone ingrowth is an important way of improving uncemented implant fixation. Enhanced fixation…”
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Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis by PROUDFOOT, D, DAVIES, J. D, SKEPPER, J. N, WEISSBERG, P. L, SHANAHAN, C. M

“…Vascular smooth muscle cells (VSMCs) in atherosclerotic lesions display an osteogenic phenotype, and calcification commonly occurs in association with lipid…”
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Trophoblast specialisations during pregnancy in the tammar wallaby, Macropus eugenii : A morphological and lectin histochemical study by Jones, C.J.P, Skepper, J.N, Renfree, M.B, Aplin, J.D

“…Abstract Introduction The tammar wallaby has a short gestation (26.5 days) and vascular modifications to expedite transport during that brief pregnancy. Here…”
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Changes in intracellular electrolyte concentrations during apoptosis induced by UV irradiation of human myeloblastic cells by Arrebola, F, Fernández-Segura, E, Campos, A, Crespo, P V, Skepper, J N, Warley, A

“…Decreases in the intracellular concentrations of both K(+) and Cl(-) have been implicated in playing a major role in the progression of apoptosis, but little…”
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Avoiding artefacts during electron microscopy of silver nanomaterials exposed to biological environments by CHEN, S., GOODE, A.E., SKEPPER, J.N., THORLEY, A.J., SEIFFERT, J.M., CHUNG, K.F., TETLEY, T.D., SHAFFER, M.S.P., RYAN, M.P., PORTER, A.E.

“…Summary Electron microscopy has been applied widely to study the interaction of nanomaterials with proteins, cells and tissues at nanometre scale. Biological…”
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Immunocytochemical strategies for electron microscopy: choice or compromise by Skepper, J. N.

“…This review attempts to describe the major immunocytochemical strategies that are in current use for transmission electron microscopy. Emphasis is placed on…”
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Characterization of the snake venom ligand [125I]‐DNP binding to natriuretic peptide receptor‐A in human artery and potent DNP mediated vasodilatation by Singh, G, Maguire, J J, Kuc, R E, Skepper, J N, Fidock, M, Davenport, A P

“…Background and purpose: The natriuretic peptides, ANP and BNP, modulate vascular smooth muscle tone in human conduit arteries. Surprisingly, the natriuretic…”
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Hydroxyapatite nano and microparticles: Correlation of particle properties with cytotoxicity and biostability by Motskin, M, Wright, D.M, Muller, K, Kyle, N, Gard, T.G, Porter, A.E, Skepper, J.N

“…Abstract Synthetic colloid and gel hydroxyapatite (HA) nanoparticles (NPs) were spray dried to form microparticles (MPs). These are intended for use as slow…”
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Calcification of Human Vascular Cells In Vitro Is Correlated With High Levels of Matrix Gla Protein and Low Levels of Osteopontin Expression by Proudfoot, Diane, Skepper, Jeremy N, Shanahan, Catherine M, Weissberg, Peter L

“…The cellular and molecular events leading to calcification in atherosclerotic lesions are unknown. We and others have shown that bone-associated proteins,…”
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A Reappraisal of the Contrasting Morphological Appearances of Villous Cytotrophoblast Cells During Early Human Pregnancy; Evidence for Both Apoptosis and Primary Necrosis by Burton, G.J, Skepper, J.N, Hempstock, J, Cindrova, T, Jones, C.J.P, Jauniaux, E

“…Villous cytotrophoblast cells display a range of morphological appearances that are assumed to reflect different stages of differentiation. Here we demonstrate…”
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Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma by Ball, R.Y., Stowers, E.C., Burton, J.H., Cary, N.R.B., Skepper, J.N., Mitchinson, M.J.

“…Sections of human atherosclerotic lesions of different stages show that, in early lesions, the acellular lipid core is usually immediately adjacent to the…”
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Post‐translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification by SCHURGERS, L. J., SPRONK, H. M. H., SKEPPER, J. N., HACKENG, T. M., SHANAHAN, C. M., VERMEER, C., WEISSBERG, P. L., PROUDFOOT, D.

“…Background: Matrix Gla protein (MGP) is a small vitamin K‐dependent protein containing five γ‐carboxyglutamic acid (Gla) residues that are believed to be…”
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Are human placental bed giant cells merely aggregates of small mononuclear trophoblast cells? An ultrastructural and immunocytochemical study by Al-Lamki, R.S., Skepper, J.N., Burton, G.J.

“…The ultrastructure of placental bed giant cells in early human pregnancies of 7–12 weeks gestational age is described. Their nature and function was further…”
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Application of environmental scanning electron microscopy to determine biological surface structure by KIRK, S.E, SKEPPER, J.N, DONALD, A.M

“…The use of environmental scanning electron microscopy in biology is growing as more becomes understood about the advantages and limitations of the technique…”
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Susceptibility of human placental syncytiotrophoblastic mitochondria to oxygen-mediated damage in relation to gestational age by WATSON, A. L, SKEPPER, J. N, JAUNIAUX, E, BURTON, G. J

“…When maintaining first trimester placental villi in organ culture under conventional normoxic conditions, we have observed widespread degeneration of the…”
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Human Endothelial Cell Storage Granules: A Novel Intracellular Site for Isoforms of the Endothelin-Converting Enzyme by Russell, Fraser D, Skepper, Jeremy N, Davenport, Anthony P

“…We have previously shown endothelin (ET)-like immunoreactive staining in Weibel-Palade bodies, storage granules that are an integral component of the regulated…”
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Effect of anti-tumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections. [Erratum: Dec 1995, v. 63 (12), p. 4966.] by Mastroeni, P, Skepper, J.N, Hormaeche, C.E

“…We reported that administration of anti-tumor necrosis factor alpha (anti-TNF-alpha) antibodies exacerbates the course of a Salmonella infection in both…”
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