Search Results - "Skeberdis, Arvydas"

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  1. 1

    Contribution of branched chain amino acids to energy production and mevalonate synthesis in cancer cells by Mikalayeva, Valeryia, Pankevičiūtė, Monika, Žvikas, Vaidotas, Skeberdis, V. Arvydas, Bordel, Sergio

    “…Leucine, isoleucine and valine, known as branched chain amino acids (BCAAs), have been reported to be degraded by different cancer cells, and their…”
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    Multi-Omics Analysis Revealed Increased De Novo Synthesis of Serine and Lower Activity of the Methionine Cycle in Breast Cancer Cell Lines by Pankevičiūtė-Bukauskienė, Monika, Mikalayeva, Valeryia, Žvikas, Vaidotas, Skeberdis, V Arvydas, Bordel, Sergio

    Published in Molecules (Basel, Switzerland) (03-06-2023)
    “…A pipeline for metabolomics, based on UPLC-ESI-MS, was tested on two malignant breast cancer cell lines of the sub-types ER(+), PR(+), and HER2(3+) (MCF-7 and…”
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    Molecular basis for potentiation of Cx36 gap junction channel conductance by n -alcohols and general anesthetics by Raškevičius, Vytautas, Jotautis, Vaidas, Rimkutė, Lina, Marandykina, Alina, Kazokaitė, Mintautė, Kairys, Visvaldas, Skeberdis, Vytenis Arvydas

    Published in Bioscience reports (28-02-2018)
    “…In our recent study, we have demonstrated that short carbon chain -alcohols (up to octanol) stimulated while long carbon chain -alcohols inhibited the…”
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    The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation by Peterman, Eric, Gibieža, Paulius, Schafer, Johnathon, Skeberdis, Vytenis Arvydas, Kaupinis, Algirdas, Valius, Mindaugas, Heiligenstein, Xavier, Hurbain, Ilse, Raposo, Graca, Prekeris, Rytis

    Published in Nature communications (18-07-2019)
    “…Once thought to be a remnant of cell division, the midbody (MB) has recently been shown to have roles beyond its primary function of orchestrating abscission…”
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    Postsynaptic Density Protein-95 Regulates NMDA Channel Gating and Surface Expression by Lin, Ying, Skeberdis, V. Arvydas, Francesconi, Anna, Bennett, Michael V. L, Zukin, R. Suzanne

    Published in The Journal of neuroscience (10-11-2004)
    “…NMDA receptors (NMDARs) colocalize with postsynaptic density protein-95 (PSD-95), a multivalent synaptic scaffolding protein and core component of the…”
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  8. 8

    Genome scale metabolic models as tools for drug design and personalized medicine by Raškevičius, Vytautas, Mikalayeva, Valeryia, Antanavičiūtė, Ieva, Ceslevičienė, Ieva, Skeberdis, Vytenis Arvydas, Kairys, Visvaldas, Bordel, Sergio

    Published in PloS one (05-01-2018)
    “…In this work we aim to show how Genome Scale Metabolic Models (GSMMs) can be used as tools for drug design. By comparing the chemical structures of human…”
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    Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency by Mickus, Rokas, Raškevičius, Vytautas, Sarapinienė, Ieva, Mikalayeva, Valeryia, Prekeris, Rytis, Skeberdis, Vytenis Arvydas

    Published in Biomedicine & pharmacotherapy (01-05-2024)
    “…Physiological and pathological processes such as homeostasis, embryogenesis, development, tumorigenesis, and cell movement depend on the intercellular…”
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  10. 10

    Fatty Acid Synthesis and Degradation Interplay to Regulate the Oxidative Stress in Cancer Cells by Mikalayeva, Valeryia, Ceslevičienė, Ieva, Sarapinienė, Ieva, Žvikas, Vaidotas, Skeberdis, Vytenis Arvydas, Jakštas, Valdas, Bordel, Sergio

    “…Both cytosolic fatty acid synthesis (FAS) and mitochondrial fatty acid oxidation (FAO) have been shown to play a role in the survival and proliferation of…”
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    Long-distance communication between laryngeal carcinoma cells by Antanavičiūtė, Ieva, Rysevaitė, Kristina, Liutkevičius, Vykintas, Marandykina, Alina, Rimkutė, Lina, Sveikatienė, Renata, Uloza, Virgilijus, Skeberdis, Vytenis Arvydas

    Published in PloS one (19-06-2014)
    “…Tunneling nanotubes and epithelial bridges are recently discovered new forms of intercellular communication between remote cells allowing their electrical…”
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    Differences in the control of basal L-type Ca2+ current by the cyclic AMP signaling cascade in frog, rat, and human cardiac myocytes by Treinys, Rimantas, Bogdelis, Andrius, Rimkutė, Lina, Jurevičius, Jonas, Skeberdis, Vytenis Arvydas

    Published in The journal of physiological sciences (01-07-2016)
    “…β-adrenergic receptors (β-ARs) mediate the positive inotropic effects of catecholamines by cAMP-dependent phosphorylation of the L-type Ca 2+ channels (LTCCs),…”
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    The effect of nutmeg essential oil constituents on Novikoff hepatoma cell viability and communication through Cx43 gap junctions by Mickus, Rokas, Jančiukė, Gintarė, Raškevičius, Vytautas, Mikalayeva, Valeryia, Matulytė, Inga, Marksa, Mindaugas, Maciūnas, Kęstutis, Bernatonienė, Jurga, Skeberdis, Vytenis Arvydas

    Published in Biomedicine & pharmacotherapy (01-03-2021)
    “…[Display omitted] •Cellular effects of essential oils from plants lack mechanistic explanations and structure–activity relationship testing.•Nutmeg essential…”
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    Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism by Antanavičiūtė, Ieva, Mikalayeva, Valeryia, Ceslevičienė, Ieva, Milašiūtė, Gintarė, Skeberdis, Vytenis Arvydas, Bordel, Sergio

    Published in Scientific reports (10-08-2017)
    “…A comparative analysis between cancer cell lines and healthy dividing cells was performed using data (289 microarrays and 50 RNA-seq samples) from 100…”
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    Midbody: From the Regulator of Cytokinesis to Postmitotic Signaling Organelle by Antanavičiūtė, Ieva, Gibieža, Paulius, Prekeris, Rytis, Skeberdis, Vytenis Arvydas

    Published in Medicina (Kaunas, Lithuania) (30-07-2018)
    “…Faithful cell division is crucial for successful proliferation, differentiation, and development of cells, tissue homeostasis, and preservation of genomic…”
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    Evaluation of Cx43 Gap Junction Inhibitors Using a Quantitative Structure-Activity Relationship Model by Matusevičiūtė, Ramona, Ignatavičiūtė, Eglė, Mickus, Rokas, Bordel, Sergio, Skeberdis, Vytenis Arvydas, Raškevičius, Vytautas

    Published in Biomedicines (01-07-2023)
    “…Gap junctions (GJs) made of connexin-43 (Cx43) are necessary for the conduction of electrical impulses in the heart. Modulation of Cx43 GJ activity may be…”
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    Relevance of HCN2-expressing human mesenchymal stem cells for the generation of biological pacemakers by Bruzauskaite, Ieva, Bironaite, Daiva, Bagdonas, Edvardas, Skeberdis, Vytenis Arvydas, Denkovskij, Jaroslav, Tamulevicius, Tomas, Uvarovas, Valentinas, Bernotiene, Eiva

    Published in Stem cell research & therapy (30-04-2016)
    “…The transfection of human mesenchymal stem cells (hMSCs) with the hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2) gene has been…”
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    FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation by Dionne, Lai Kuan, Peterman, Eric, Schiel, John, Gibieža, Paulius, Skeberdis, Vytenis Arvydas, Jimeno, Antonio, Wang, Xiao-Jing, Prekeris, Rytis

    Published in Journal of cell science (01-12-2017)
    “…The post-mitotic midbody (MB) is a remnant of cytokinesis that can be asymmetrically inherited by one of the daughter cells following cytokinesis. Until…”
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    Hyperthermia Differently Affects Connexin43 Expression and Gap Junction Permeability in Skeletal Myoblasts and HeLa Cells by Herdegen, Thomas, Stankevičius, Edgaras, Mildažienė, Vida, Antanavičiūtė, Ieva, Skeberdis, Vytenis Arvydas

    Published in Mediators of Inflammation (01-01-2014)
    “…Stress kinases can be activated by hyperthermia and modify the expression level and properties of membranous and intercellular channels. We examined the role…”
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