Search Results - "Skalweit, Marion J."

Early Insights into the Interactions of Different β-Lactam Antibiotics and β-Lactamase Inhibitors against Soluble Forms of Acinetobacter baumannii PBP1a and Acinetobacter sp. PBP3 by Papp-Wallace, Krisztina M, Senkfor, Baui, Gatta, Julian, Chai, Weirui, Taracila, Magdalena A, Shanmugasundaram, Veerabahu, Han, Seungil, Zaniewski, Richard P, Lacey, Brian M, Tomaras, Andrew P, Skalweit, Marion J, Harris, Michael E, Rice, Louis B, Buynak, John D, Bonomo, Robert A

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Substitutions at Position 105 in SHV Family β-Lactamases Decrease Catalytic Efficiency and Cause Inhibitor Resistance by MEI LI, CONKLIN, Benjamin C, TARACILA, Magdalena A, HUTTON, Rebecca A, SKALWEIT, Marion J

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N152G, -S, and -T Substitutions in CMY-2 β-Lactamase Increase Catalytic Efficiency for Cefoxitin and Inactivation Rates for Tazobactam by Skalweit, Marion J, Li, Mei, Conklin, Benjamin C, Taracila, Magdalena A, Hutton, Rebecca A

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Penicillin Sulfone Inhibitors of Class D β-Lactamases by DRAWZ, Sarah M, BETHEL, Christopher R, BONOMO, Robert A, DOPPALAPUDI, Venkata R, SHERI, Anjaneyulu, SUNDAR RAM REDDY PAGADALA, HUJER, Andrea M, SKALWEIT, Marion J, ANDERSON, Vernon E, CHEN, Shu G, BUYNAK, John D

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Outpatient Parenteral Antibiotic Therapy in Older Adults by Oliver, Nora T., Skalweit, Marion J.

“…Outpatient parenteral antimicrobial therapy (OPAT) for older adults is a complex process that involves multiple stakeholders and care coordination, but it is a…”
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Antibiotic-Resistant Infections and Treatment Challenges in the Immunocompromised Host: An Update by Dumford, 3rd, Donald, Skalweit, Marion J

“…This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ…”
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An unusual case of underlying rilpivirine resistance in an antiretroviral-naïve man with AIDS by Skalweit, Marion J

“…Primary resistance mutations to second generation HIV non-nucleoside reverse transcriptase inhibitors are rare in HIV-infected persons in the US (estimated at…”
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A rare case of immune reconstitution inflammatory syndrome presenting as secondary syphilis by Khatri, Asma, Skalweit, Marion J

“…Immune reconstitution syndrome has rarely been reported in the context of syphilis infection. We report a patient with AIDS (CD4 42 cells/mm(3), viral load…”
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Effect of asparagine substitutions in the YXN loop of a class C β-lactamase of Acinetobacter baumannii on substrate and inhibitor kinetics by Skalweit, Marion J, Li, Mei, Taracila, Magda A

“…Class C cephalosporinases are a growing threat, and inhibitors of these enzymes are currently unavailable. Studies exploring the YXN loop asparagine in the…”
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Bulgecin A as a β-lactam enhancer for carbapenem-resistant Pseudomonas aeruginosa and carbapenem-resistant Acinetobacter baumannii clinical isolates containing various resistance mechanisms by Skalweit, Marion J, Li, Mei

“…Genetic screening of (PSDA) and (ACB) reveals genes that confer increased susceptibility to β-lactams when disrupted, suggesting novel drug targets. One such…”
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Profile of ceftolozane/tazobactam and its potential in the treatment of complicated intra-abdominal infections by Skalweit, Marion J

“…Drug-resistant pathogens have gained a foothold especially in the most vulnerable patient populations, hospitalized and immunocompromised individuals…”
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Ibrutinib Therapy and Mycobacterium chelonae Skin and Soft Tissue Infection by Dousa, Khalid M, Babiker, Ahmed, Van Aartsen, Daniel, Shah, Neel, Bonomo, Robert A, Johnson, John L, Skalweit, Marion J

“…Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase approved for the treatment of B-cell malignancies. There is growing concern about the risk…”
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Mycobacterial Tenosynovitis After Sea Urchin Spine Injury in an Immunocompromised Patient by Vargas, Christina R, Kanwar, Anubhav, Dousa, Khalid M, Skalweit, Marion J, Rowe, David, Gatherwright, James

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Enhancing Resistance to Cephalosporins in Class C β-Lactamases: Impact of Gly214Glu in CMY-2 by Endimiani, Andrea, Doi, Yohei, Bethel, Christopher R, Taracila, Magdalena, Adams-Haduch, Jennifer M, O’Keefe, Alexandra, Hujer, Andrea M, Paterson, David L, Skalweit, Marion J, Page, Malcolm G. P, Drawz, Sarah M, Bonomo, Robert A

“…The biochemical properties of CMY-32, a class C enzyme possessing a single-amino acid substitution in the Ω loop (Gly214Glu), were compared to those of the…”
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SAME is different: a case report and literature review of Staphylococcus aureus metastatic endophthalmitis by Nixdorff, Neil A, Tang, Johnny, Mourad, Ronda, Skalweit, Marion J

“…We present a case of methicillin-sensitive Staphylococcus aureus metastatic endophthalmitis (SAME) that developed from a bacteremia. We compare this to a…”
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The Importance of the trans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase Variants by Ke, Wei, Rodkey, Elizabeth A., Sampson, Jared M., Skalweit, Marion J., Sheri, Anjaneyulu, Pagadala, Sundar Ram Reddy, Nottingham, Michael D., Buynak, John D., Bonomo, Robert A., van den Akker, Focco

“…The ability of bacteria to express inhibitor‐resistant (IR) β‐lactamases is stimulating the development of novel inhibitors of these enzymes. The…”
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Antibiotic-Resistant Infections and Treatment Challenges in the Immunocompromised Host by Dumford, Donald, Skalweit, Marion J.

“…This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ…”
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Bulgecin A as a [beta]-lactam enhancer for carbapenem-resistant Pseudomonas aeruginosa and carbapenem-resistant Acinetobacter baumannii clinical isolates containing various resistance mechanisms by Skalweit, Marion J, Li, Mei

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Bulgecin A as a β-lactam enhancer for carbapenem-resistantPseudomonas aeruginosa and carbapenem-resistant Acinetobacter baumannii clinical isolates containing various resistance mechanisms by Skalweit, Marion J, Li, Mei

“…Genetic screening of Pseudomonas aeruginosa (PSDA) and Acinetobacter ­baumannii (ACB) reveals genes that confer increased susceptibility to β-lactams when…”
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715. Bulgecin A lowers Imipenem MICs in Clinical MDR Acinetobacter baumannii (ACB) Strains by Skalweit, Marion J, Rojas, Laura J, Bonomo, Robert A, Dik, David A, Tomoshige, Shusuke, Mobashery, Shahriar

“…Abstract Background Genetic screening of ACB has revealed genes that confer increased susceptibility to β-lactams when these genes are disrupted suggesting…”
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