Search Results - "Skakuj, Kacper"

Catalyst-Controlled Wacker-Type Oxidation: Facile Access to Functionalized Aldehydes by Wickens, Zachary K, Skakuj, Kacper, Morandi, Bill, Grubbs, Robert H

“…The aldehyde-selective oxidation of alkenes bearing diverse oxygen groups in the allylic and homoallylic position was accomplished with a nitrite-modified…”
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Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy by Qin, Lei, Wang, Shuya, Dominguez, Donye, Long, Alan, Chen, Siqi, Fan, Jie, Ahn, Jihae, Skakuj, Kacper, Huang, Ziyin, Lee, Andrew, Mirkin, Chad, Zhang, Bin

“…Although the strategy of therapeutic vaccination for the treatment of prostate cancer has advanced to and is available in the clinic (Sipuleucel-T), the…”
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Chemically Tuning the Antigen Release Kinetics from Spherical Nucleic Acids Maximizes Immune Stimulation by Skakuj, Kacper, Teplensky, Michelle H, Wang, Shuya, Dittmar, Jasper W, Mirkin, Chad A

“…Cancer vaccine structure is emerging as an important design factor that offers tunable parameters to enhance the targeted immune response. We report the impact…”
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Conjugation Chemistry-Dependent T‑Cell Activation with Spherical Nucleic Acids by Skakuj, Kacper, Wang, Shuya, Qin, Lei, Lee, Andrew, Zhang, Bin, Mirkin, Chad A.

“…Spherical nucleic acids (SNAs) can be potent sequence-specific stimulators of antigen presenting cells (APCs). When loaded with peptide antigens, they can be…”
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Rational vaccinology with spherical nucleic acids by Wang, Shuya, Qin, Lei, Yamankurt, Gokay, Skakuj, Kacper, Huang, Ziyin, Chen, Peng-Cheng, Dominguez, Donye, Lee, Andrew, Zhang, Bin, Mirkin, Chad A.

“…In the case of cancer immunotherapy, nanostructures are attractive because they can carry all of the necessary components of a vaccine, including both antigen…”
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The Power of Spheres by Mirkin, Chad A., Laramy, Christine, Skakuj, Kacper

“…DNA or RNA molecules, arranged into spherical shapes, can attack brain cancers and other illnesses that evade conventional drug design. DNA or RNA molecules,…”
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Mercury-Free Automated Synthesis of Guanidinium Backbone Oligonucleotides by Skakuj, Kacper, Bujold, Katherine E, Mirkin, Chad A

“…A new method for synthesizing deoxynucleic guanidine (DNG) oligonucleotides that uses iodine as a mild and inexpensive coupling reagent is reported. This…”
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Light‐Responsive Colloidal Crystals Engineered with DNA by Zhu, Jinghan, Lin, Haixin, Kim, Youngeun, Yang, Muwen, Skakuj, Kacper, Du, Jingshan S., Lee, Byeongdu, Schatz, George C., Van Duyne, Richard P., Mirkin, Chad A.

“…A novel method for synthesizing and photopatterning colloidal crystals via light‐responsive DNA is developed. These crystals are composed of 10–30 nm gold…”
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Light‐Activated Reactivity of Nitrones with Amino Acids and Proteins by Toste, F. Dean, Skakuj, Kacper, Iglhaut, Maximilian, Shao, Qian, Garcia, Francisco, Huang, Bo-Yang, Brittain, Scott, Nesvizhskii, Alexey, Schirle, Markus, Nomura, Daniel

“…Controlled modifications of amino acids are an indispensable tool for advancing fundamental and translational research based on peptides and proteins. Yet, we…”
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Advancing Spherical Nucleic Acid Therapeutics Through Chemical Modifications of DNA by Skakuj, Kacper

“…Chemical modifications of oligonucleotides (ONs) have advanced these molecules towards clinical approvals. On their own, native ONs have poor pharmacokinetic…”
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Light-Responsive Colloidal Crystals Engineered with DNA by Zhu, Jinghan, Lin, Haixin, Kim, Youngeun, Yang, Muwen, Skakuj, Kacper, Du, Jingshan S., Lee, Byeongdu, Schatz, George C., Van Duyne, Richard P., Mirkin, Chad A.

“…A novel method for synthesizing and photopatterning colloidal crystals via light-responsive DNA is developed. These crystals are composed of 10-30 nm gold…”
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X‑ray Diffraction of Intermetallic Compounds: A Physical Chemistry Laboratory Experiment by Varberg, Thomas D, Skakuj, Kacper

“…Here we describe an experiment for the undergraduate physical chemistry laboratory in which students synthesize the intermetallic compounds AlNi and AlNi3 and…”
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Enhancing Antigen Delivery Using Spherical Nucleic Acidsfor Optimal Prostate Cancer Immunotherapy by Qin, Lei, Wang, Shuya, Dominguez, Donye, Long, Alan, Chen, Siqi, Fan, Jie, Ahn, Ji Hae, Skakuj, Kacper, Lee, Andrew, Mirkin, Chad, Zhang, Bin

“…Prostate cancer ranks as the second leading cause of cancer-related death in the United States in men. For patients with metastatic or recurrent disease,…”
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Light‐Activated Reactivity of Nitrones with Amino Acids and Proteins by Toste, F. Dean, Skakuj, Kacper, Iglhaut, Maximilian, Shao, Qian, Garcia, Francisco, Huang, Bo-Yang, Brittain, Scott, Nesvizhskii, Alexey, Schirle, Markus, Nomura, Daniel

“…Controlled modifications of amino acids are an indispensable tool for advancing fundamental and translational research based on peptides and proteins. Yet, we…”
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Automated Synthesis and Purification of Guanidine-Backbone Oligonucleotides by Skakuj, Kacper, Bujold, Katherine E, Mirkin, Chad A

“…This protocol describes a method based on iodine and a base as mild coupling reagents to synthetize deoxyribonucleic guanidines (DNGs)-oligodeoxynucleotide…”
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The Power of Spheres: DNA or RNA molecules, arranged into spherical shapes, can attack brain cancers and other illnesses that evade conventional drug design by Kacper Skakuj, Christine Laramy, Chad Mirkin

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The Power of Spheres by Mirkin, Chad A, Laramy, Christine, Skakuj, Kacper

“…Mirkin et al explain how DNA or RNA molecules, arranged into spherical shapes, can attack brain cancers and other illnesses that evade conventional drug…”
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The Power of Spheres by Laramy, Christine, Mirkin, Chad A, Skakuj, Kacper

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