Search Results - "Skachilova, S. Ya"

Aminoethane Sulfonic Acid Magnesium Salt Inhibits Ca2+ Entry Through NMDA Receptor Ion Channel In Vitro by Turovsky, E. A., Blinova, E. V., Semeleva, E. V., Zinchenko, V. P., Astashev, M. E., Blinov, D. S., Skachilova, S. Ya, Geras’kina, M. M., Lebedev, A. B., Gromova, I. A.

“…The effect of a cerebroprotective agent magnesium bis-aminoethanesulfonate (laboratory code FS-LKhT-317) on intracellular calcium concentration was studied by…”
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Neuroprotective and Antiamnestic Effects of a New Drug Emopag in Rats by Yasnetsov, V. V., Voronina, T. A., Skachilova, S. Ya, Yasnetsov, V. V.

“…Emopag, a new drug, preventively administered in doses of 10 and 30 mg/kg/day over 4 days produced a pronounced neuroprotective effect in the model of brain…”
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DRUGS DEVELOPED AT «ARC BASS» WITH M.D. MASHKOVSKII LEAD (REVIEW) by Skachilova, S. Ya, Ermakova, G. A., Zheltukhin, N. K., Zueva, E. F., Davydova, N. K.

“…Introduction. There are presented data on drugs development with M.D. Mashkovskii lead. There are given materials on drugs belonging to important…”
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The effect of a new 3-hydroxypyridine derivative LHT-2-20 on free radical oxidation in experimental periodontitis by Poryadin, G. V., Zakhvatov, A. N., Yasnetsov, V. V., Skachilova, S. Ya, Khaydar, D. A., Tarasova, T. V., Zakharkin, I. A., Parshina, A. Yu, Simakina, E. A.

“…Aim. To study the effect of a new complex compound LHT-2-20 (2-ethyl-6-methyl-3-hydroxypyridine-2-(3benzoyl phenyl)-propanoate) on free radical oxidation in…”
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Synthesis and In Silico Prediction of the Molecular-Targeting Anti-EGFR Action of a Novel Dihydroacridinone by Epishkina, A. A., Bogoslovskaya, E. V., Pakina, V. A., Osipiantz, A. I., Kutorkina, E. A., Livin, E. A., Tumutolova, O. M., Skachilova, S. Ya, Blinov, K. D., Semeleva, E. V., Shimanovsky, D. N., Fedoseikin, I. V., Tolstov, M. V., Blinova, E. V., Shikh, E. V., Blinov, D. S.

“…The synthesis and in silico prediction of the molecular-targeted anti-EGFR inhibitory activity of a novel dihydroacridinone derivative are reported…”
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Prospects for the development of bronchodilators by Skachilova, S. Ya, Shilova, E. V., Chuchalin, A. G.

“…The review considers and evaluates the methodology for the design of antiasthmatic bronchodilators, selective stimulants of β 2 -adrenergic receptors in…”
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Preparation and Mechanism of the Antitumor Action of a 4H-Aminochromene Compound by Samyshina, E. A., Blinova, E. V., Kudryavtsev, M. Yu, Shimanovskii, D. N., Skachilova, S. Ya, Epishkina, A. A., Blinov, D. S., Tumutolova, O. M., Simakina, E. A., Shifrin, Yu. A., Deryabina, O. N., Shilova, E. V., Makhrova, A. A., Arutyunyan, K. K.

“…We report here studies of the antitumor action of a 4 H -aminochromene compound in a xenograft model of ALK-expressing lung adenocarcinoma in humanized nude…”
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BRONCHODILATOR AND TOCOLYTIC FEATURES OF β2-ADRENOCEPTOR AGONISTS by S. Ya. Skachilova, E. V. Shilova, V. M. Pavlov, T. N. Molostova

“…The issues (aspects) of bronchodilator and tocolytic actions of β₂-adrenoceptor agonists are reviewed. The data on short-acting and new long-acting β₂-agonists…”
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Reductive Amination of Sterically Hindered Arylaminoketones Using a Modified Leuckart Reaction by Skachilova, S. Ya, Zheltukhin, N. K., Sergeev, V. N., Davydova, N. K.

“…The Leuckart reaction offers a fast and convenient method for synthesizing various formamides, amines, and large numbers of biologically active compounds and…”
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Synthesis of biologically active compounds and biopharmaceutical aspects of polymorphic and solvatomorphic modifications by Skachilova, S. Ya, Shilova, E. V., Mitrokhin, N. M.

“…The design of new highly efficient drugs for the treatment of various diseases is an important problem and a top-priority task in medicinal chemistry in most…”
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Experimental study of the effectiveness of local anesthetic activity of a new dimethylphenylacetamide-containing pharmaceutical composition in chronic periodontitis by Blinova, E V, Semeleva, E V, Shilova, A M, Vediaeva, A P, Blinov, D S, Skachilova, S Ya, Vasil'ev, Yu L, Vasilkina, O V, Samishina, E A, Meylanova, R D

“…Novel anaesthetic formulation LHT-15-32 was studied. The experimental study involved 66 white mice, 15 Rana radibunda frogs and 50 male Sprague Dawley rats…”
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STUDYING SOME PHARMACOLOGICAL EFFECTS OF NEW 3-HYDROXYPYRIDINE DERIVATIVE by Yasnetsov, V V, Tsublova, E G, Yasnetsov, Vic V, Skachilova, S Ya, Karsanova, S K, Ivanov, Yu V

“…It was established that a new 3-hydroxypyridine (3-HP) derivative, 2-ethyl-6-methyl-3-hydroxypyridine L-aspartate (3-HP), in small doses (1 and 5 mg/kg)…”
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Aminoethane Sulfonic Acid Magnesium Salt Inhibits Ca 2+ Entry Through NMDA Receptor Ion Channel In Vitro by Turovsky, E A, Blinova, E V, Semeleva, E V, Zinchenko, V P, Astashev, M E, Blinov, D S, Skachilova, S Ya, Geras'kina, M M, Lebedev, A B, Gromova, I A

“…The effect of a cerebroprotective agent magnesium bis-aminoethanesulfonate (laboratory code FS-LKhT-317) on intracellular calcium concentration was studied by…”
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Comparative analysis of acute toxicity of amino acid-containing antiarrhythmics by Napalkova, S. M., Artem'eva, O. V., Kostin, Ya. V., Skachilova, S. Ya, Gireva, N. N.

“…Acute toxicity of amino acid-containing antiarrhythmic agents is experimentally studied in mice. Introduction of amino acids into the antiarrhythmic molecules…”
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VESTIBULAR AND THERMOPROTECTIVE PROPERTIES OF A NEW ACTOPROTECTOR by Yasnetsov, V V, Tsublova, E G, Yasnetsov, Vik V, Skachilova, S Ya, Karsanova, S K, Chelnaya, N A

“…In experiments with rats, a new 3-hydroxypyridine (3-HP) derivative--2-ethyl-6-methyl-3-hydroxypyridine L-asparaginate (30 mg/kg)--exhibited a strong…”
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Composite film materials based on poly(D,L-Lactide) and acexamic acid by Nashchekina, Yu. A., Zorin, I. M., Fetin, P. A., Skachilova, S. Ya, Bilibin, A. Yu

“…The influence of the hydrophilicity and molecular mass of poly( D,L -lactide) on the solubility of acexamic acid in the polylactide film and on the rate of its…”
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Synthesis and pharmacological properties of a new 3-hydroxypyridine derivative by Yasnetsov, Vic. V., Skachilova, S. Ya, Sernov, L. N., Voronina, T. A., Yasnetsov, V. V.

“…The new 3-hydroxypyridine derivative 2-ethyl-6-methyl-3-hydroxypyridinium N -acetyl-L-glutamate (EMOP-AG) was synthesized. It was established that EMOP-AG (10…”
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Beta-2 Lgonists for Inhalation in the Form of Dry Powders by Garkavaya, T. N., Petrugova, N. P., Skachilova, S. Ya, Pavlov, V. M., Sokolov, A. S., Ershov, Yu. A., Shilova, E. V.

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Synthesis and Antiarrhythmic Activity of 2-Diethylamino-2′,6′-Dimethylphenylacetamide Derivatives by Sernov, L. N., Skachilova, S. Ya, Blinov, D. S., Druzhinina, V. V., Kostin, Ya. V., Shilova, E. V.

“…Data on the syntheses and structures of a series of new derivatives of 2-diethylamino-2',6'-dimethylphenylacetamide are described. The results of an…”
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Synthesis and some properties of 6-(ω-aroylbutylthio)purines by Gromov, M. Yu, Skachilova, S. Ya, Aleksandrova, E. V., Kochergin, P. M.

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