Search Results - "Skaalure, Stacey C."
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Scaffolding Biomaterials for 3D Cultivated Meat: Prospects and Challenges
Published in Advanced science (01-01-2022)“…Cultivating meat from stem cells rather than by raising animals is a promising solution to concerns about the negative externalities of meat production. For…”
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2
Quantitative volumetric Raman imaging of three dimensional cell cultures
Published in Nature communications (22-03-2017)“…The ability to simultaneously image multiple biomolecules in biologically relevant three-dimensional (3D) cell culture environments would contribute greatly to…”
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Modulating temporal and spatial oxygenation over adherent cellular cultures
Published in PloS one (03-09-2009)“…Oxygen is a key modulator of many cellular pathways, but current devices permitting in vitro oxygen modulation fail to meet the needs of biomedical research. A…”
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4
Age impacts extracellular matrix metabolism in chondrocytes encapsulated in degradable hydrogels
Published in Biomedical materials (Bristol) (01-04-2012)“…Encapsulation of autologous adult cartilage cells (chondrocytes) in hydrolytically degradable hydrogels may provide a clinically viable tissue engineering…”
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5
Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning
Published in Advanced materials (Weinheim) (01-10-2018)“…Tissue engineering has offered unique opportunities for disease modeling and regenerative medicine; however, the success of these strategies is dependent on…”
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6
An Enzyme-Sensitive PEG Hydrogel Based on Aggrecan Catabolism for Cartilage Tissue Engineering
Published in Advanced healthcare materials (01-02-2015)“…A new cartilage‐specific degradable hydrogel based on photoclickable thiol‐ene poly(ethylene glycol) (PEG) hydrogels is presented. The hydrogel crosslinks are…”
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7
Nanoscale Molecular Quantification of Stem Cell–Hydrogel Interactions
Published in ACS nano (22-12-2020)“…A common approach to tailoring synthetic hydrogels for regenerative medicine applications involves incorporating RGD cell adhesion peptides, yet assessing the…”
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Temporally degradable collagen–mimetic hydrogels tuned to chondrogenesis of human mesenchymal stem cells
Published in Biomaterials (01-08-2016)“…Abstract Tissue engineering strategies for repairing and regenerating articular cartilage face critical challenges to recapitulate the dynamic and complex…”
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Semi-interpenetrating networks of hyaluronic acid in degradable PEG hydrogels for cartilage tissue engineering
Published in Acta biomaterialia (01-08-2014)“…Hydrolytically biodegradable poly(ethylene glycol) (PEG) hydrogels offer a promising platform for chondrocyte encapsulation and tuning degradation for…”
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Activatable cell-biomaterial interfacing with photo-caged peptides
Published in Chemical science (Cambridge) (28-01-2019)“…Spatio-temporally tailoring cell-material interactions is essential for developing smart delivery systems and intelligent biointerfaces. Here we report new…”
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11
Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β‑Sheet Fibrils
Published in ACS nano (26-09-2017)“…Determining the structural origins of amyloid fibrillation is essential for understanding both the pathology of amyloidosis and the rational design of…”
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Determination of the polymer-solvent interaction parameter for PEG hydrogels in water: Application of a self learning algorithm
Published in Polymer (Guilford) (01-06-2015)“…Concentrating on the case of poly(ethylene glycol) hydrogels, this paper introduces a methodology that enables a natural integration between the development of…”
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Tuning Reaction and Diffusion Mediated Degradation of Enzyme-Sensitive Hydrogels
Published in Advanced healthcare materials (18-02-2016)“…Enzyme‐sensitive hydrogels are promising for cell encapsulation and tissue engineering, but result in complex spatiotemporal degradation behavior that is…”
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Physiological osmolarities do not enhance long‐term tissue synthesis in chondrocyte‐laden degradable poly(ethylene glycol) hydrogels
Published in Journal of biomedical materials research. Part A (01-06-2015)“…Encapsulating chondrocytes in synthetic and degradable hydrogels for cartilage tissue engineering enables tuning of scaffold degradation, but provides no…”
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15
Three dimensional live cell lithography
Published in Optics express (22-04-2013)“…We investigate holographic optical trapping combined with step-and-repeat maskless projection stereolithography for fine control of 3D position of living cells…”
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Activatable cell-biomaterial interfacing with photo-caged peptidesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04725a
Published 23-01-2019“…Spatio-temporally tailoring cell-material interactions is essential for developing smart delivery systems and intelligent biointerfaces. Here we report new…”
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Activatable cell–biomaterial interfacing with photo-caged peptides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04725a
Published in Chemical science (Cambridge) (16-11-2018)“…We report an effective strategy to design activatable cell–material interfacing systems enabling photo-modulated cellular entry of cargoes and cell adhesion…”
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Tuning hydrogel degradation for cartilage tissue engineering
Published 2014“…Cartilage tissue engineering using biodegradable scaffolds as carriers for cartilage cells (chondrocytes) presents a promising strategy to regenerate cartilage…”
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Dissertation