Radial artery calcification in predicting coronary calcification and atherosclerosis burden

Abstract Background Atherosclerosis is a systemic arterial disease with heterogeneous involvement in all vascular beds, however studies examining the relationship between coronary and radial artery calcification are lacking. The purpose of this study was to assess the relationship between the two si...

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Published in:European heart journal Vol. 43; no. Supplement_2
Main Authors: Achim, A, Kakonyi, K, Nagy, F, Jambrik, Z, Varga, A, Nemes, A, Sk Chan, J, Toth, G, Ruzsa, Z
Format: Journal Article
Language:English
Published: 03-10-2022
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Summary:Abstract Background Atherosclerosis is a systemic arterial disease with heterogeneous involvement in all vascular beds, however studies examining the relationship between coronary and radial artery calcification are lacking. The purpose of this study was to assess the relationship between the two sites and the prognostic value of radial artery calcification (RC) for coronary artery disease. Methods and results This is a single-center, retrospective cross-sectional study based on doppler ultrasound of radial artery (RUS) and coronary artery angiography (CAG). We included a total of 202 patients undergoing RUS during distal radial access and CAG at the same procedure, between December 2020 and May 2021, from which 103 were found having RC during RUS (RC-group) and 99 without (NRC-group). Coronary calcifications were evaluated either by angiography examination (moderate and severe), positive CT (>100 Agatson units) or intracoronary imaging (IVUS, OCT). A significant correlation was observed between radial calcification and coronary calcification variables (67.3%, vs 32.7% – p=0.001). The correlation between risk factors such as age, smoking, chronic kidney disease and diabetes mellitus was higher while sex did not play a role. The need of PCI and/or CABG was higher in the RC-group (60% vs 44%, p=0.02). RC therefore predicts the extent and severity of coronary artery disease. Conclusion RC may be frequently associated with calcific coronary plaques. These findings highlight the potential beneficial examination of radial arteries whenever CAD is suspected. Funding Acknowledgement Type of funding sources: None.
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehac544.2314