Search Results - "Skålhegg, Bjørn"
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T Cell Metabolism in Infection
Published in Frontiers in immunology (14-03-2022)“…T lymphocytes (T cells) are divided into two functionally different subgroups the CD4+ T helper cells (Th) and the CD8+ cytotoxic T lymphocytes (CTL). Adequate…”
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The Molecular Basis for Specificity at the Level of the Protein Kinase a Catalytic Subunit
Published in Frontiers in endocrinology (Lausanne) (12-09-2018)“…Assembly of multi enzyme complexes at subcellular localizations by anchoring- and scaffolding proteins represents a pivotal mechanism for achieving…”
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Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits
Published in PloS one (12-04-2013)“…3',5'-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein…”
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T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions
Published in PloS one (28-07-2016)“…Immune responses often take place where nutrients and O2 availability are limited. This has an impact on T cell metabolism and influences activation and…”
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Similar performance after intake of carbohydrate plus whey protein and carbohydrate only in the early phase after non‐exhaustive cycling
Published in Scandinavian journal of medicine & science in sports (01-07-2023)“…Aim The aim of the present study was to compare performance 5 h after a 90‐min endurance training session when either carbohydrate only or carbohydrate with…”
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Protein intake in the early recovery period after exhaustive exercise improves performance the following day
Published in Journal of applied physiology (1985) (01-12-2018)“…The aim of the present study was to investigate the effect of protein and carbohydrate ingestion during early recovery from exhaustive exercise on performance…”
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Carbohydrate Ingestion during Prolonged Cycling Improves Next-Day Time Trial Performance and Alters Amino Acid Concentrations
Published in Medicine and science in sports and exercise (01-12-2023)“…Exercise with low carbohydrate availability increases protein degradation, which may reduce subsequent performance considerably. The present study aimed to…”
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IL-7 is expressed and secreted by human skeletal muscle cells
Published in American Journal of Physiology: Cell Physiology (01-04-2010)“…In addition to generating movement, skeletal muscle may have a function as a secretory organ. The aim of the present study was to identify novel proteins with…”
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The Tails of Protein Kinase A
Published in Molecular pharmacology (01-04-2022)“…Protein kinase A (PKA) is a holoenzyme consisting of a regulatory (R)-subunit dimer and two catalytic (C)-subunits. There are two major families of C-subunits,…”
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10
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
Published in PloS one (25-07-2017)“…The 3',5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase, or protein kinase A (PKA), pathway is one of the most versatile and best studied…”
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The association between body mass index and vulvar and vaginal cancer incidence: findings from a large Norwegian cohort study
Published in Cancer causes & control (27-10-2024)“…There is limited evidence of potential associations between body mass index (BMI) and risk of vulvar and vaginal cancer. We explored these associations in a…”
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Risk and survival in colorectal cancer with increasing body mass index: A nationwide population‐based cohort study
Published in Colorectal disease (01-03-2023)“…Aim The aim was to explore potential associations between the body mass index (BMI) and the risk of colorectal cancer (CRC), including subsites of the colon,…”
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Body mass index and pancreatic adenocarcinoma: A nationwide registry-based cohort study
Published in Scandinavian journal of surgery (01-03-2023)“…Background and objective: An association between body mass index (BMI) and pancreatic cancer is suggested in observational studies. However, further studies…”
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The Effect of Alginate Encapsulated Plant-Based Carbohydrate and Protein Supplementation on Recovery and Subsequent Performance in Athletes
Published in Nutrients (01-01-2024)“…The main purpose of this study was to investigate the effect of a novel alginate-encapsulated carbohydrate-protein (CHO-PRO ratio 2:1) supplement (ALG) on…”
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3PO inhibits inflammatory NFκB and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3
Published in PloS one (2020)“…Inhibition of the key glycolytic activator 6-phosphofructokinase 2/fructose-2,6-bisphosphatase-3 (PFKFB3) by 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one…”
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Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease
Published in BMC cancer (03-05-2024)“…Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an advanced…”
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Cancer risk and survival according to body mass index in hepatobiliary malignancies: a nationwide registry-based cohort study
Published in HPB (Oxford, England) (01-11-2023)“…The aim of this study was to explore the associations between BMI and cancer of the liver, bile ducts, and gallbladder. A registry-based cohort study was…”
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Identification and characterization of a novel glutaminase inhibitor
Published in FEBS open bio (01-01-2022)“…In humans, there are two forms of glutaminase (GLS), designated GLS1 and GLS2. These enzymes catalyse the conversion of glutamine to glutamate. GLS1 exists as…”
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Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome
Published in American journal of human genetics (05-11-2020)“…PRKACA and PRKACB code for two catalytic subunits (Cα and Cβ) of cAMP-dependent protein kinase (PKA), a pleiotropic holoenzyme that regulates numerous…”
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Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
Published in Frontiers in immunology (19-06-2017)“…The IL-17-producing CD4 T helper cell (Th17) differentiation is affected by stimulation of the aryl hydrocarbon receptor (AhR) pathway and by hypoxia-inducible…”
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