Search Results - "Sjöberg, Sara"

Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages by Zhou, Yi, Yu, Xueqing, Chen, Huimei, Sjöberg, Sara, Roux, Joséphine, Zhang, Lijun, Ivoulsou, Al-Habib, Bensaid, Farid, Liu, Cong-Lin, Liu, Jian, Tordjman, Joan, Clement, Karine, Lee, Chih-Hao, Hotamisligil, Gokhan S., Libby, Peter, Shi, Guo-Ping

“…Mast cells (MCs) contribute to the pathogenesis of obesity and diabetes. This study demonstrates that leptin deficiency slants MCs toward anti-inflammatory…”
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IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice by Wang, Jing, Cheng, Xiang, Xiang, Mei-Xiang, Alanne-Kinnunen, Mervi, Wang, Jian-An, Chen, Han, He, Aina, Sun, Xinghui, Lin, Yan, Tang, Ting-Ting, Tu, Xin, Sjöberg, Sara, Sukhova, Galina K, Liao, Yu-Hua, Conrad, Daniel H, Yu, Lunyin, Kawakami, Toshiaki, Kovanen, Petri T, Libby, Peter, Shi, Guo-Ping

“…IgE has a key role in the pathogenesis of allergic responses through its ability to activate mast cells via the receptor FcεR1. In addition to mast cells, many…”
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Cathepsin K Deficiency Reduces Elastase Perfusion–Induced Abdominal Aortic Aneurysms in Mice by Sun, Jiusong, Sukhova, Galina K, Zhang, Jie, Chen, Han, Sjöberg, Sara, Libby, Peter, Xia, Mingcan, Xiong, Na, Gelb, Bruce D, Shi, Guo-Ping

“…OBJECTIVE—Cathepsin K (CatK) is one of the most potent mammalian elastases. We have previously shown increased expression of CatK in human abdominal aortic…”
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Cathepsin L Activity Is Essential to Elastase Perfusion–Induced Abdominal Aortic Aneurysms in Mice by Sun, Jiusong, Sukhova, Galina K, Zhang, Jie, Chen, Han, Sjöberg, Sara, Libby, Peter, Xiang, Meixiang, Wang, Jianan, Peters, Christoph, Reinheckel, Thomas, Shi, Guo-Ping

“…OBJECTIVE—The development of abdominal aortic aneurysms (AAA) requires extensive aortic wall matrix degradation. Human AAA lesions express high levels of…”
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Cathepsin G activity lowers plasma LDL and reduces atherosclerosis by Wang, Jing, Sjöberg, Sara, Tang, Ting-Ting, Öörni, Katariina, Wu, Wenxue, Liu, Conglin, Secco, Blandine, Tia, Viviane, Sukhova, Galina K., Fernandes, Cleverson, Lesner, Adam, Kovanen, Petri T., Libby, Peter, Cheng, Xiang, Shi, Guo-Ping

“…Cathepsin G (CatG), a serine protease present in mast cells and neutrophils, can produce angiotensin-II (Ang-II) and degrade elastin. Here we demonstrate…”
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The Endogenous Estradiol Metabolite 2-Methoxyestradiol Reduces Atherosclerotic Lesion Formation in Female Apolipoprotein E-Deficient Mice by Bourghardt, Johan, Bergström, Göran, Krettek, Alexandra, Sjöberg, Sara, Borén, Jan, Tivesten, Åsa

“…Estradiol, the major endogenous estrogen, reduces experimental atherosclerosis and metabolizes to 2-methoxyestradiol in vascular cells. Currently undergoing…”
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Cysteine Protease Cathepsins in Atherosclerosis and Abdominal Aortic Aneurysm by Sjöberg, Sara, Shi, Guo-Ping

“…Extracellular matrix remodeling is an important mechanism in the initiation and progression of cardiovascular diseases. Cysteine protease cathepsins are among…”
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A guanidine‐rich regulatory oligodeoxynucleotide improves type‐2 diabetes in obese mice by blocking T‐cell differentiation by Cheng, Xiang, Wang, Jing, Xia, Ni, Yan, Xin‐Xin, Tang, Ting‐Ting, Chen, Han, Zhang, Hong‐Jian, Liu, Juan, Kong, Wen, Sjöberg, Sara, Folco, Eduardo, Libby, Peter, Liao, Yu‐Hua, Shi, Guo‐Ping

“…T lymphocytes exhibit pro‐inflammatory or anti‐inflammatory activities in obesity and diabetes, depending on their subtypes. Guanidine‐rich immunosuppressive…”
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IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice by Wang, Jing, Cheng, Xiang, Xiang, Mei-Xiang, Alanne-Kinnunen, Mervi, Wang, Jian-An, Chen, Han, He, Aina, Sun, Xinghui, Lin, Yan, Tang, Ting-Ting, Tu, Xin, Sjöberg, Sara, Sukhova, Galina K, Liao, Yu-Hua, Conrad, Daniel H, Yu, Lunyin, Kawakami, Toshiaki, Kovanen, Petri T, Libby, Peter, Shi, Guo-Ping

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Applying the Theory of Planned Behavior to Predict Dairy Product Consumption by Older Adults by Kim, Kyungwon, Reicks, Marla, Sjoberg, Sara

“…Objective: The purpose of this study was to explain intention to consume dairy products and consumption of dairy products by older adults using the Theory of…”
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CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk by Lei, Haixin, Sjöberg‐Margolin, Sara, Salahshor, Sima, Werelius, Barbro, Jandáková, Eva, Hemminki, Kari, Lindblom, Annika, Vořechovský, Igor

“…Mutations and diminished expression of the E‐cadherin gene (CDH1) have been identified in a number of epithelial malignancies. Although somatic CDH1 mutations…”
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Pharmaceutical stabilization of mast cells attenuates experimental atherogenesis in low-density lipoprotein receptor-deficient mice by Wang, Jing, Sjöberg, Sara, Tia, Viviane, Secco, Blandine, Chen, Han, Yang, Min, Sukhova, Galina K, Shi, Guo-Ping

“…Abstract Mast cells (MCs) contribute to atherogenesis by releasing pro-inflammatory mediators to activate vascular cells and other inflammatory cells. This…”
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Augmented levels of CD44 in macrophages from atherosclerotic subjects: A possible IL-6–CD44 feedback loop? by Hägg, Daniel, Sjöberg, Sara, Hultén, Lillemor Mattsson, Fagerberg, Björn, Wiklund, Olov, Rosengren, Annika, Carlsson, Lena M.S, Borén, Jan, Svensson, Per-Arne, Krettek, Alexandra

“…Abstract The cell-adhesion molecule CD44 likely participates in atherosclerosis development. We have shown previously that pro-inflammatory cytokines affect…”
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CD44-deficiency on hematopoietic cells limits T-cell number but does not protect against atherogenesis in LDL receptor-deficient mice by Sjöberg, Sara, Eriksson, Einar E, Tivesten, Åsa, Carlsson, Annelie, Klasson, Anna, Levin, Max, Borén, Jan, Krettek, Alexandra

“…Abstract Objective Vascular and inflammatory cells express adhesion molecule CD44. We demonstrated previously that enhanced CD44 localizes in human…”
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CD44 - a new cardiovascular drug target or merely an innocent bystander? by Krettek, Alexandra, Sjöberg, Sara

“…CD44, short for cluster of differentiation 44, is an adhesion molecule of the hyaluronate receptor family. Expressed on the surface of most vertebrate cells,…”
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Circulating soluble CD44 is higher among women than men and is not associated with cardiovascular risk factors or subclinical atherosclerosis by Sjöberg, Sara, Fogelstrand, Linda, Hulthe, Johannes, Fagerberg, Björn, Krettek, Alexandra

“…In the present study, the associations between the plasma concentration of soluble CD44 (sCD44), sex, cardiovascular risk factors, and ultrasound-assessed…”
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IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe^sup -/-^ mice by Wang, Jing, Cheng, Xiang, Xiang, Mei-Xiang, Alanne-Kinnunen, Mervi, Wang, Jian-An, Chen, Han, He, Aina, Sun, Xinghui, Lin, Yan, Tang, Ting-Ting, Tu, Xin, Sjöberg, Sara, Sukhova, Galina K, Liao, Yu-Hua, Conrad, Daniel H, Yu, Lunyin, Kawakami, Toshiaki, Kovanen, Petri T, Libby, Peter, Shi, Guo-Ping

“…IgE has a key role in the pathogenesis of allergic responses through its ability to activate mast cells via the receptor FcεR1. In addition to mast cells, many…”
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The bone morphogenetic protein type Ib receptor is a major mediator of glial differentiation and cell survival in adult hippocampal progenitor cell culture by Brederlau, A, Faigle, R, Elmi, M, Zarebski, A, Sjöberg, S, Fujii, M, Miyazono, K, Funa, K

“…Bone morphogenetic proteins (BMPs) act as growth regulators and inducers of differentiation. They transduce their signal via three different type I receptors,…”
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Multimodality treatment of 128 patients with locally advanced breast carcinoma in the era of mammography screening using standard polychemotherapy with 5‐fluorouracil, epirubicin, and cyclophosphamide by Karlsson, Ylva A., Malmström, Per O., Hatschek, Thomas, Fornander, Tommy G., Söderberg, Martin, Bengtsson, Nils‐Olof, Jansson, Tomas E., Sjöberg, Sara M., Bergh, Jonas C.

“…BACKGROUND Locally advanced breast carcinoma is associated with a poor prognosis. With single treatment modalities, i.e., surgery and/or radiation therapy,…”
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IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in [Apoe.sup.-/-] mice by Wang, Jing, Cheng, Xiang, Xiang, Mei-Xiang, Alanne-Kinnunen, Mervi, Wang, Jian-An, Chen, Han, He, Aina, Sun, Xinghui, Lin, Yan, Tang, Ting-Ting, Tu, Xin, Sjoberg, Sara, Sukhova, Galina K, Liao, Yu-Hua, Conrad, Daniel H, Yu, Lunyin, Kawakami, Toshiaki, Kovanen, Petri T, Libby, Peter, Shi, Guo-Ping

“…IgE has a key role in the pathogenesis of allergic responses through its ability to activate mast cells via the receptor FcζR1. In addition to mast cells, many…”
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