Search Results - "Sjakste, N"

Experimental and human population studies of DNA lesions in healthy individuals by Sjakste, N.

“…DNA damage is a valuable biomarker in human molecular epidemiology being associated with many diseases. However, the level of DNA damage is influenced also by…”
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DNA-binding studies of AV-153, an antimutagenic and DNA repair-stimulating derivative of 1,4-dihydropiridine by Buraka, E., Chen, C. Yu-Chian, Gavare, M., Grube, M., Makarenkova, G., Nikolajeva, V., Bisenieks, I., Brūvere, I., Bisenieks, E., Duburs, G., Sjakste, N.

“…•Antimutagenic 1,4-dihydropiridine derivative AV-153 interacts directly with DNA.•Antimutagenic 1,4-dihydropiridine derivative AV-153 intercalates to DNA in a…”
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Guanine-quadruplex-enriched sequences in the tight DNA-protein complexes of barley seedlings by Sjakste, T., Leonova, E., Petrovs, R., Röder, M., Sjakste, N.

“…Recent achievements in studies of the three-dimensional interactions between genes caused significant re-evaluation of the nucleus structure in general. The…”
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Structural and functional significance of microsatellites by Sjakste, T., Paramonova, N., Sjakste, N.

“…Here we review literature data on impact of microsatellite repeats on DNA and chromatin structure and the results of studies on association between the length…”
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Tightly bound to DNA proteins: Possible universal substrates for intranuclear processes by Sjakste, N., Bielskiene, K., Bagdoniene, L., Labeikyte, D., Gutcaits, A., Vassetzky, Y., Sjakste, T.

“…Tightly bound to DNA proteins (TBPs) are a protein group that remains attached to DNA after its deproteinization by phenol, chloroform or salting-out. TBP are…”
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DNA-binding studies of a series of novel water-soluble derivatives of 1,4-dihydropyridine by Leonova, E., Rostoka, E., Baumane, L., Borisovs, V., Smelovs, E., Bisenieks, I., Brūvere, I., Bisenieks, E., Duburs, G., Sjakste, N.

“…Aim. to determine DNA interaction modes for a series of 1,4-dihydropyridines with different biological activities synthesized in the Latvian Institute of…”
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Study of association between polymorphisms in the PSMB5 (rs11543947) and PSMA3 (rs2348071) genes and multiple sclerosis in Latvians by Kalnina, J., Paramonova, N., Sjakste, N., Sjakste, T.

“…Functional realization of many signalling proteins and transcription factors implicated in the development and progression of multiple sclerosis is mediated by…”
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Possible involvement of DNA strand breaks in regulation of cell differentiation by Sjakste, N, Sjakste, T

“…The present review summarizes data on the accumulation of DNA strand breaks in differentiating cells. Large 50 Kbp free DNA fragments were observed by several…”
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Phosphatase activity in barley proteins tightly bound to DNA and its development-dependent changes by Bielskienė, K., Labeikytė, D., Sjakste, N., Bagdonienė, L., Juodka, B.

“…The tightly bound proteins (TBPs), a protein group that remains attached to DNA either covalently or noncovalently after deproteinization, have been found in…”
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Tightly-bound to DNA proteins in rat experimental hepatomas and normal liver cells by Labeikytė, D, Borutinskaitė, V, Legzdiņš, N, Sjakste, N

“…Proteins tightly bound to DNA (TBP) comprise a group of proteins that remain bound to DNA even after harsh deproteinization procedures. The amount of these…”
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Proteins tightly bound to DNA: New data and old problems by Sjakste, N, Bagdoniene, L, Gutcaits, A, Labeikyte, D, Bielskiene, K, Trapina, I, Muiznieks, I, Vassetzky, Y, Sjakste, T

“…Proteins tightly bound to DNA (TBP) comprise a group of proteins that remain bound to DNA after usual deproteinization procedures such as salting out and…”
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Association of Microsatellite Polymorphisms of the Human 14q13.2 Region with Type 2 Diabetes Mellitus in Latvian and Finnish Populations by Sjakste, T., Kalis, M., Poudziunas, I., Pirags, V., Lazdins, M., Groop, L., Sjakste, N.

“…Summary A polymorphic microsatellite in intron 6 of the human proteasome core particle PSMA6 gene (HSMS006), and four other microsatellites localized upstream…”
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The influence of mildronate on peripheral neuropathy and some characteristics of glucose and lipid metabolism in rat streptozotocin-induced diabetes mellitus model by Sokolovska, J, Rumaks, J, Karajeva, N, Grīnvalde, D, Shapirova, J, Kluša, V, Kalvinsh, I, Sjakste, N

“…Streptozotocin (STZ) was used to induce the diabetic rat model. STZ rats were treated with mildronate (100 mg/kg daily, per os or intraperitoneally for 6…”
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Paradoxical effects of two oximes on nitric oxide production by purified NO synthases, in cell culture and in animals by Sjakste, N., Andrianov, V.G., Boucher, J.-L., Shestakova, I., Baumane, L., Dzintare, M., Meirena, D., Kalvinsh, I.

“…We have studied the impact of two novel compounds TO-85 (2,6-di-(α-aziridino-α-hydroxyiminomethyl)pyridine and TO-133 (bis-(diaziridinoglyoximato)copper),…”
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The influence of mildronate on peripheral neuropathy and some characteristics of glucose and lipid metabolism in rats with the streptozotocin model of diabetes mellitus by Sokolovska, J., Rumaks, J., Karajeva, N., Grinvalde, D., Sharipova, J., Kluša, V., Kalvinsh, I., Sjakste, N.

“…Rats with the streptozotocin (STZ) model of diabetes mellitus were treated with mildronate (100 mg/kg daily, per os or intraperitoneally) for 6 weeks. Body…”
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Increased synthesis of nitric oxide in rat brain cortex due to halogenated volatile anesthetics confirmed by EPR spectroscopy by Baumane, L., Dzintare, M., Zvejniece, L., Meirena, D., Lauberte, L., Sile, V., Kalvinsh, I., Sjakste, N.

“…Background: Halogenated volatile anesthetics (HVAs) are considered to be inhibitors of nitric oxide synthase (NOS). On other hand, NO mediates the vasodilation…”
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Nuclear matrix proteins and hereditary diseases by Sjakste, N., Sjakste, T.

“…The review summarizes literature data on alterations of structure or expression of different nuclear matrix proteins in hereditary syndromes. From the point of…”
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Nuclear matrix proteins and hereditary diseases by Sjakste, N, Sjakste, T

“…The review summarizes literature data on alterations of structure or expression of different nuclear matrix proteins in hereditary syndromes. From the point of…”
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SNPs of PSMA6 gene--investigation of possible association with myocardial infarction and type 2 diabetes mellitus by Sjakste, T, Poudziunas, I, Ninio, E, Perret, C, Pirags, V, Nicaud, V, Lazdins, M, Evanss, A, Morrison, C, Cambien, F, Sjakste, N

“…In our preceding studies we have identified microsatellite polymorphisms inside the PSMA6 gene and in its 5' upstream region. Following the observed…”
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SNPs of the PSMA6 gene: Investigation of possible association with myocardial infarction and type 2 diabetes mellitus by Sjakste, T., Poudziunas, I., Ninio, E., Perret, C., Pirags, V., Nicaud, V., Lazdins, M., Evans, A., Morrison, C., Cambien, F., Sjakste, N.

“…In our preceding studies, we have identified microsatellite polymorphisms inside the PSMA6 gene and in its 5' upstream region. Following the observed…”
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