Search Results - "Sjaarda, Calvin P"
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Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
Published in Scientific reports (27-06-2022)“…The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) was met with rapid development of robust molecular-based detection assays. Many…”
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Phylogenomics reveals viral sources, transmission, and potential superinfection in early-stage COVID-19 patients in Ontario, Canada
Published in Scientific reports (12-02-2021)“…The emergence and rapid global spread of SARS-CoV-2 demonstrates the importance of infectious disease surveillance, particularly during the early stages. Viral…”
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Interplay between maternal Slc6a4 mutation and prenatal stress: a possible mechanism for autistic behavior development
Published in Scientific reports (18-08-2017)“…The low activity allele of the maternal polymorphism, 5HTTLPR, in the serotonin transporter, SLC6A4 , coupled with prenatal stress is reported to increase the…”
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Author Correction: Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
Published in Scientific reports (19-08-2022)Get full text
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Exome sequencing identifies de novo splicing variant in XRCC6 in sporadic case of autism
Published in Journal of human genetics (01-03-2020)“…Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with heterogeneity in presentation, genetic etiology, and clinical outcome. Although…”
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Changes in social environment impact primate gut microbiota composition
Published in Animal microbiome (13-11-2024)“…The gut microbiota (GM) has proven to be essential for both physical health and mental wellbeing, yet the forces that ultimately shape its composition remain…”
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Colloidal structure of honey and its influence on antibacterial activity
Published in Comprehensive reviews in food science and food safety (01-03-2021)“…Honey colloidal structure emerges as a new trend in research on honey functions since it became recognized as a major factor altering bioactivity of honey…”
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Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada
Published in mSphere (05-05-2021)“…Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions…”
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Evaluation of 5 Polymerase Chain Reaction Assays for the Detection of Mpox Virus
Published in The Journal of infectious diseases (26-03-2024)“…In 2022, the global dissemination of mpox virus (MPXV) outside endemic regions prompted the expansion of diagnostic testing worldwide. This study assesses the…”
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Induction of lcc2 expression and activity by Agaricus bisporus provides defence against Trichoderma aggressivum toxic extracts
Published in Microbial biotechnology (01-11-2015)“…Summary Laccases are used by fungi for several functions including defence responses to stresses associated with attack by other fungi. Laccase activity…”
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Comparison of SARS-CoV-2 Viral Loads in the Nasal Mucosa of Patients Infected With BA.1, BA.2, or BA.5 Omicron Lineages
Published in Open forum infectious diseases (01-12-2022)“…Abstract Lower viral loads were observed in the upper respiratory tract of patients infected with BA.1, whereas patients infected with BA.2 and BA.5 had…”
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Prevalence of Low-Frequency, Antiviral Resistance Variants in SARS-CoV-2 Isolates in Ontario, Canada, 2020-2023
Published in JAMA network open (03-07-2023)“…Nirmatrelvir-ritonavir is an oral antiviral medication that improves outcomes in SARS-CoV-2 infections. However, there is concern that antiviral resistance…”
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Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic Hypersensitivity
Published in Cellular and molecular gastroenterology and hepatology (01-01-2024)“…Abdominal pain is a major symptom of diseases that are associated with microbial dysbiosis, including irritable bowel syndrome and inflammatory bowel disease…”
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Absence of lysogeny in wild populations of Erwinia amylovora and Pantoea agglomerans
Published in Microbial biotechnology (01-05-2015)“…Summary Lytic bacteriophages are in development as biological control agents for the prevention of fire blight disease caused by Erwinia amylovora. Temperate…”
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De novo duplication on chromosome 19 observed in nuclear family displaying neurodevelopmental disorders
Published in Cold Spring Harbor molecular case studies (01-06-2020)“…Pleiotropy and variable expressivity have been cited to explain the seemingly distinct neurodevelopmental disorders due to a common genetic etiology within the…”
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Relationship of family history conditions and early signs of autism spectrum disorder in low and high-risk infants
Published in Research in autism spectrum disorders (01-09-2019)“…•We compared family history conditions of infants at high-risk and low risk for ASD.•We examined the relationship between family history conditions and scores…”
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Homozygosity for the 10-repeat dopamine transporter (DAT1) allele is associated with reduced EEG response in males with ASD
Published in Research in autism spectrum disorders (01-04-2019)“…•Individuals with ASD and their undiagnosed relatives present similar EEG responses.•COMT and OXTR polymorphisms not associated with any specific EEG…”
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Induction of lcc 2 expression and activity by A garicus bisporus provides defence against T richoderma aggressivum toxic extracts
Published in Microbial biotechnology (01-11-2015)“…Summary Laccases are used by fungi for several functions including defence responses to stresses associated with attack by other fungi. Laccase activity…”
Get full text
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T richoderma toxins and A garicus laccase
Published in Microbial biotechnology (01-11-2015)“…Laccases are used by fungi for several functions including defence responses to stresses associated with attack by other fungi. Laccase activity changes and…”
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Absence of lysogeny in wild populations of E rwinia amylovora and P antoea agglomerans
Published in Microbial biotechnology (01-05-2015)“…Summary Lytic bacteriophages are in development as biological control agents for the prevention of fire blight disease caused by E rwinia amylovora . Temperate…”
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