Search Results - "Sixt, Katherine M."

Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity by Subramaniam, Srinivasa, Sixt, Katherine M, Barrow, Roxanne, Snyder, Solomon H

“…Huntington's disease (HD) is caused by a polyglutamine repeat in the protein huntingtin (Htt) with mutant Htt (mHtt) expressed throughout the body and…”
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Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β by Tripathi, Veenu, Sixt, Katherine M., Gao, Shaojian, Xu, Xuan, Huang, Jing, Weigert, Roberto, Zhou, Ming, Zhang, Ying E.

“…In advanced stages of cancers, TGF-β promotes tumor progression in conjunction with inputs from receptor tyrosine kinase pathways. However, mechanisms that…”
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Rhes, a Physiologic Regulator of Sumoylation, Enhances Cross-sumoylation between the Basic Sumoylation Enzymes E1 and Ubc9 by Subramaniam, Srinivasa, Mealer, Robert G., Sixt, Katherine M., Barrow, Roxanne K., Usiello, Alessandro, Snyder, Solomon H.

“…We recently reported that the small G-protein Rhes has the properties of a SUMO-E3 ligase and mediates mutant huntingtin (mHtt) cytotoxicity. We now…”
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HSP90 regulates cell survival via inositol hexakisphosphate kinase-2 by Chakraborty, Anutosh, Koldobskiy, Michael A, Sixt, Katherine M, Juluri, Krishna R, Mustafa, Asif K, Snowman, Adele M, van Rossum, Damian B, Patterson, Randen L, Snyder, Solomon H

“…Heat-shock proteins (HSPs) are abundant, inducible proteins best known for their ability to maintain the conformation of proteins and to refold damaged…”
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Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1 by Zhu, Shanshan, Goeres, Jacqueline, Sixt, Katherine M., Békés, Miklós, Zhang, Xiang-Dong, Salvesen, Guy S., Matunis, Michael J.

“…Vertebrates express three small ubiquitin-related modifiers (SUMO-1, SUMO-2, and SUMO-3) that are conjugated in part to unique subsets of proteins and,…”
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miRNA signature of mouse helper T cell hyper-proliferation by Sommers, Connie L, Rouquette-Jazdanian, Alexandre K, Robles, Ana I, Kortum, Robert L, Merrill, Robert K, Li, Wenmei, Nath, Nandan, Wohlfert, Elizabeth, Sixt, Katherine M, Belkaid, Yasmine, Samelson, Lawrence E

“…Helper T cells from a mutant mouse model, LAT Y136F, hyper-proliferate and cause a severe lymphoproliferative disease that kills the mice by six months of age…”
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Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β by Tripathi, Veenu, Sixt, Katherine M., Gao, Shaojian, Xu, Xuan, Huang, Jing, Weigert, Roberto, Zhou, Ming, Zhang, Ying E.

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Regulation of c-Src Nonreceptor Tyrosine Kinase Activity by Bengamide A through Inhibition of Methionine Aminopeptidases by Hu, Xiaoyi, Dang, Yongjun, Tenney, Karen, Crews, Phillip, Tsai, Chiawei W., Sixt, Katherine M., Cole, Philip A., Liu, Jun O.

“…Methionine aminopeptidases (MetAPs) remove the N-terminal initiator methionine during protein synthesis, a prerequisite step for N-terminal myristoylation…”
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Abstract 3032: Direct regulation of alternative splicing by Smad3 through PCBP1 is essential to the tumor-promoting role of transforming growth factor beta1 by Tripathi, Veenu, Sixt, Katherine M., Xu, Xuan, Zhang, Ying E.

“…Abstract In advanced stages of cancers, TGF- β promotes tumor progression in conjunction with inputs from receptor tyrosine kinase pathways. However, the…”
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HSP9O regulates cell survival via inositol hexakisphosphate kinase-2 by Chakraborty, Anutosh, Koldobskiy, Michael A, Sixt, Katherine M, Juluri, Krishna R, Mustafa, Asif K, Snowman, Adele M, Rossum, Damian B van, Patterson, Randen L, Snyder, Solomon H

“…Heat-shock proteins (HSPs) are abundant, inducible proteins best known for their ability to maintain the conformation of proteins and to refold damaged…”
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miRNA Signature of Mouse Helper T Cell Hyper-Proliferation. e66709 by Sommers, Connie L, Rouquette-Jazdanian, Alexandre K, Robles, Ana I, Kortum, Robert L, Merrill, Robert K, Li, Wenmei, Nath, Nandan, Wohlfert, Elizabeth, Sixt, Katherine M, Belkaid, Yasmine

“…Helper T cells from a mutant mouse model, LAT Y136F, hyper-proliferate and cause a severe lymphoproliferative disease that kills the mice by six months of age…”
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CK2 and Sumo1 phosphorylation: A role in cell survival by Sixt, Katherine M

“…CK2 is an ubiquitously expressed, constitutively active protein kinase with over 300 target substrates identified to date. It has been shown to be upregulated…”
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CK2 and Sumo1 phosphorylation: A role in cell survival by Sixt, Katherine M

“…CK2 is an ubiquitously expressed, constitutively active protein kinase with over 300 target substrates identified to date. It has been shown to be upregulated…”
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Regulation of c-Src Non-receptor Tyrosine Kinase Activity by Bengamide A Through Inhibition of Methionine Aminopeptidases by Hu, Xiaoyi, Dang, Yongjun, Tenney, Karen, Crews, Phillip, Tsai, Chiawei W., Sixt, Katherine M., Cole, Philip A., Liu, Jun O.

“…Methionine aminopeptidases (MetAPs) remove the N -terminal initiator methionine during protein synthesis, a pre-requisite step for N -terminal myristoylation…”
Get full text