Search Results - "Six, Karel"

Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion—part I by Verreck, Geert, Six, Karel, Van den Mooter, Guy, Baert, Lieven, Peeters, Jef, Brewster, Marcus E.

“…Solid dispersions containing different ratios of itraconazole and hydroxypropylmethylcellulose (HPMC) were prepared by solvent casting. Based on dose,…”
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Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion by Six, Karel, Daems, Tinne, de Hoon, Jan, Van Hecken, Anne, Depre, Marleen, Bouche, Marie-Paule, Prinsen, Paul, Verreck, Geert, Peeters, Jef, Brewster, Marcus E., Van den Mooter, Guy

“…The aim of this study was to investigate the performance of three new solid dispersion formulations of itraconazole in human volunteers in comparison with…”
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Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers by Six, Karel, Verreck, Geert, Peeters, Jef, Brewster, Marcus, Van Den Mooter, Guy

“…Solid dispersions were prepared of itraconazole-Eudragit E100, itraconazole-PVPVA64, and itraconazole-Eudragit E100/PVPVA64 using a corotating twin-screw…”
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Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion, Part II by SIX, Karel, BERGHMANS, Hugo, PEETERS, Jef, BREWSTER, Marcus, VAN DEN MOOTER, Guy, LEUNER, Christian, DRESSMAN, Jennifer, VAN WERDE, Kristof, MULLENS, Jules, BENOIST, Luc, THIMON, Mireille, MEUBLAT, Laurent, VERRECK, Geert

“…This study was done to elucidate the physical and pharmaceutical properties of itraconazole-HPMC dispersions and the influence of water on the phase…”
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Investigation of thermal properties of glassy itraconazole: identification of a monotropic mesophase by Six, Karel, Verreck, Geert, Peeters, Jef, Binnemans, Koen, Berghmans, Hugo, Augustijns, Patrick, Kinget, Renaat, Van den Mooter, Guy

“…The purpose of the present work is the elucidation of two endothermic transitions at 74 and 90°C, respectively, observed during differential scanning…”
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Identification of phase separation in solid dispersions of itraconazole and Eudragit® E100 using microthermal analysis by SIX, Karel, MURPHY, John, WEUTS, Ilse, CRAIG, Duncan Q. M, VERRECK, Geert, PEETERS, Jef, BREWSTER, Marcus, VAN DEN MOOTER, Guy

“…To evaluate the phase separation in itraconazole/Eudragit E100 solid dispersions prepared by hot-stage extrusion. Extrudates were prepared using a corotating…”
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