Search Results - "Sivagnanalingam, Umayal"

Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines by Kim, Kyu Kwang, Singh, Rakesh K., Khazan, Negar, Kodza, Arif, Singh, Niloy A., Jones, Aaron, Sivagnanalingam, Umayal, Towner, Mary, Itamochi, Hiroaki, Turner, Rachael, Moore, Richard G.

“…Forchlorfenuron (FCF) is a synthetic plant cytokinin widely used in agriculture to promote fruit size, that paradoxically inhibits proliferation, migration,…”
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Novel Small Molecule MEK Inhibitor URML-3881 Enhances Cisplatin Sensitivity in Clear Cell Ovarian Cancer by Rowswell-Turner, Rachael B., Rutishauser, Jennifer A., Kim, Kyu Kwang, Khazan, Negar, Sivagnanalingam, Umayal, Jones, Aaron M., Singh, Rakesh K., Moore, Richard G.

“…Advanced clear cell ovarian cancer (CCOC) is a highly fatal malignancy with a scarcity of effective treatment options. CCOC is inherently chemotherapy…”
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Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia by Sivagnanalingam, Umayal, Balys, Marlene, Eberhardt, Allison, Wang, Nancy, Myers, Jason R, Ashton, John M, Becker, Michael W, Calvi, Laura M, Mendler, Jason H

“…Cytogenetically normal acute myeloid leukemia (CN-AML) patients harboring RUNX1 mutations have a dismal prognosis with anthracycline/cytarabine-based…”
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Index case of acute myeloid leukemia in a family harboring a novel CEBPA germ line mutation by Ram, Jodi, Flamm, Gabrielle, Balys, Marlene, Sivagnanalingam, Umayal, Rothberg, Paul G., Iqbal, Anwar, Myers, Jason R., Corbett, Anthony, Ashton, John M., Mendler, Jason H.

“…•The persistence of a CEBPA mutation at the time of complete remission warrants germ line analysis.•Not all patients harboring germ line CEBPA mutations have a…”
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Myeloid derived suppressor cells in cancer, premalignancy and inflammation: A roadmap to cancer immunoprevention by Sivagnanalingam, Umayal, Beatty, Pamela L., Finn, Olivera J.

“…The ultimate success of any form of cancer therapy or cancer prevention depends on its ability to engage the power of the immune system to completely eliminate…”
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Malignancy Assessment Using Gene Identification in Captured Cells Algorithm for the Prediction of Malignancy in Women With a Pelvic Mass by Moore, Richard George, Khazan, Negar, Coulter, Madeline Ann, Singh, Rakesh, Miller, Michael Craig, Sivagnanalingam, Umayal, DuBeshter, Brent, Angel, Cynthia, Liu, Cici, Seto, Kelly, Englert, David, Meachem, Philip, Kim, Kyu Kwang

“…To evaluate the detection of malignancy in women with a pelvic mass by using multiplexed gene expression analysis of cells captured from peripheral blood. This…”
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HE4 Overexpression by Ovarian Cancer Promotes a Suppressive Tumor Immune Microenvironment and Enhanced Tumor and Macrophage PD-L1 Expression by Rowswell-Turner, Rachael B, Singh, Rakesh K, Urh, Anze, Yano, Naohiro, Kim, Kyu Kwang, Khazan, Negar, Pandita, Ravina, Sivagnanalingam, Umayal, Hovanesian, Virginia, James, Nicole E, Ribeiro, Jennifer R, Kadambi, Sindhuja, Linehan, David C, Moore, Richard G

“…Ovarian cancer is a highly fatal malignancy characterized by early chemotherapy responsiveness but the eventual development of resistance. Immune targeting…”
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Sex, race, and socioeconomic distinctions in incisional hernia management by Handzel, Robert M., Huckaby, Lauren V., Dadashzadeh, Esmaeel R., Silver, David, Rieser, Caroline, Sivagnanalingam, Umayal, Rosengart, Matthew R., van der Windt, Dirk J.

“…We sought to explore the impact of sex, race, and insurance status on operative management of incisional hernias. A retrospective cohort study was conducted to…”
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A Novel Xenograft Model of Cytogenetically Normal Acute Myeloid Leukemia Harboring RUNX1 and ASXL1 Mutations Demonstrates Residual Disease after Anthracycline/Cytarabine-Based Chemotherapy by Sivagnanalingam, Umayal, Balys, Marlene, Eberhardt, Allison, Wang, Nancy, Ashton, John M., Mendler, Jason H.

“…Introduction: Cytogenetically normal acute myeloid leukemia (CN-AML) patients harboring RUNX1 mutations have a poor prognosis with standard,…”
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Distinct Properties of Leukemia Stem Cells in Primary Refractory Acute Myeloid Leukemia by Mendler, Jason H., Balys, Marlene, Sivagnanalingam, Umayal, Eberhardt, Allison, Thorne, Korinne, Ho, Tzu-Chieh, LaMere, Mark W., Moore, Samuel, McMurray, Helene, Myers, Jason R., Ashton, John M., O'Dwyer, Kristen, Liesveld, Jane L., Calvi, Laura M., Becker, Michael W.

“…Introduction: Acute Myeloid Leukemia (AML) patients who are refractory to induction chemotherapy (RF) have a dismal prognosis. Properties of AML cell…”
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Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia: e0132375 by Sivagnanalingam, Umayal, Balys, Marlene, Eberhardt, Allison, Wang, Nancy, Myers, Jason R, Ashton, John M, Becker, Michael W, Calvi, Laura M, Mendler, Jason H

“…Cytogenetically normal acute myeloid leukemia (CN-AML) patients harboring RUNX1 mutations have a dismal prognosis with anthracycline/cytarabine-based…”
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