Search Results - "Siu, Karen K.W"

Simultaneous acquisition of dual analyser-based phase contrast X-ray images for small animal imaging by Kitchen, Marcus J, Pavlov, Konstantin M, Hooper, Stuart B, Vine, David J, Siu, Karen K.W, Wallace, Megan J, Siew, Melissa L.L, Yagi, Naoto, Uesugi, Kentaro, Lewis, Rob A

“…Abstract Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries…”
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Imaging lung aeration and lung liquid clearance at birth by Hooper, Stuart B, Kitchen, Marcus J, Wallace, Megan J, Yagi, Naoto, Uesugi, Kentaro, Morgan, Michael J, Hall, Chris, Siu, Karen K.W, Williams, Ivan M, Siew, Melissa, Irvine, Sarah C, Pavlov, Konstantin, Lewis, Robert A

“…Aeration of the lung and the transition to air-breathing at birth is fundamental to mammalian life and initiates major changes in cardiopulmonary physiology…”
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Measurement of hard X-ray coherence in the presence of a rotating random-phase-screen diffuser by Morgan, Kaye S., Irvine, Sarah C., Suzuki, Yoshio, Uesugi, Kentaro, Takeuchi, Akihisa, Paganin, David M., Siu, Karen K.W.

“…A suitably large coherence area is important in coherent X-ray optics, when using techniques such as interferometry or phase contrast imaging (PCI). The work…”
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X-ray phase imaging with a paper analyzer by Morgan, Kaye S., Paganin, David M., Siu, Karen K. W.

“…We present a simple x-ray phase imaging method that utilizes the sample-induced distortion of a high contrast random intensity pattern to quantitatively…”
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Quantitative single-exposure x-ray phase contrast imaging using a single attenuation grid by Morgan, Kaye S, Paganin, David M, Siu, Karen K W

“…A single-exposure quantitative method of x-ray phase contrast imaging, suitable for animal in vivo observations, is described and shown experimentally both for…”
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Quantification of heterogeneity in lung disease with image-based pulmonary function testing by Stahr, Charlene S., Samarage, Chaminda R., Donnelley, Martin, Farrow, Nigel, Morgan, Kaye S., Zosky, Graeme, Boucher, Richard C., Siu, Karen K. W., Mall, Marcus A., Parsons, David W., Dubsky, Stephen, Fouras, Andreas

“…Computed tomography (CT) and spirometry are the mainstays of clinical pulmonary assessment. Spirometry is effort dependent and only provides a single global…”
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Synchrotron-based dynamic computed tomography of tissue motion for regional lung function measurement by Dubsky, Stephen, Hooper, Stuart B., Siu, Karen K. W., Fouras, Andreas

“…During breathing, lung inflation is a dynamic process involving a balance of mechanical factors, including trans-pulmonary pressure gradients, tissue…”
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The sharpest tools in the box? Quantitative analysis of conodont element functional morphology by Jones, David, Evans, Alistair R., Siu, Karen K. W., Rayfield, Emily J., Donoghue, Philip C. J.

“…Conodonts have been considered the earliest skeletonizing vertebrates and their mineralized feeding apparatus interpreted as having performed a tooth function…”
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Inspiration regulates the rate and temporal pattern of lung liquid clearance and lung aeration at birth by Siew, Melissa L, Wallace, Megan J, Kitchen, Marcus J, Lewis, Robert A, Fouras, Andreas, te Pas, Arjan B, Yagi, Naoto, Uesugi, Kentaro, Siu, Karen K. W, Hooper, Stuart B

“…1 Department of Physiology, 2 School of Physics, 3 Monash Centre for Synchrotron Science, and 4 Department of Biological Engineering, Monash University,…”
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In Vivo X-Ray Imaging Reveals Improved Airway Surface Hydration after a Therapy Designed for Cystic Fibrosis by MORGAN, Kaye S, DONNELLEY, Martin, FOURAS, Andreas, YAGI, Naoto, SUZUKI, Yoshio, TAKEUCHI, Akihisa, UESUGI, Kentaro, BOUCHER, Richard C, SIU, Karen K. W, PARSONS, David W

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Altered Lung Motion is a Sensitive Indicator of Regional Lung Disease by Fouras, Andreas, Allison, Beth J., Kitchen, Marcus J., Dubsky, Stephen, Nguyen, Jayne, Hourigan, Kerry, Siu, Karen K. W., Lewis, Rob A., Wallace, Megan J., Hooper, Stuart B.

“…Since lung diseases adversely affect airflow during breathing, they must also alter normal lung motion, which can be exploited to detect these diseases…”
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Quantitative x-ray phase-contrast imaging using a single grating of comparable pitch to sample feature size by Morgan, Kaye S, Paganin, David M, Siu, Karen K W

“…The ability to quantitatively retrieve transverse phase maps during imaging by using coherent x rays often requires a precise grating or analyzer-crystal-based…”
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Biotin Synthase Exhibits Burst Kinetics and Multiple Turnovers in the Absence of Inhibition by Products and Product-Related Biomolecules by Farrar, Christine E, Siu, Karen K. W, Howell, P. Lynne, Jarrett, Joseph T

“…Biotin synthase (BS) is a member of the “SAM radical” superfamily of enzymes, which catalyze reactions in which the reversible or irreversible oxidation of…”
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Live small-animal X-ray lung velocimetry and lung micro-tomography at the Australian Synchrotron Imaging and Medical Beamline by Murrie, Rhiannon P., Morgan, Kaye S., Maksimenko, Anton, Fouras, Andreas, Paganin, David M., Hall, Chris, Siu, Karen K. W., Parsons, David W., Donnelley, Martin

“…The high flux and coherence produced at long synchrotron beamlines makes them well suited to performing phase‐contrast X‐ray imaging of the airways and lungs…”
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Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo by Donnelley, Martin, Morgan, Kaye S., Siu, Karen K. W., Farrow, Nigel R., Stahr, Charlene S., Boucher, Richard C., Fouras, Andreas, Parsons, David W.

“…To determine the efficacy of potential cystic fibrosis (CF) therapies we have developed a novel mucociliary transit (MCT) measurement that uses synchrotron…”
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Tracking extended mucociliary transport activity of individual deposited particles: longitudinal synchrotron X-ray imaging in live mice by Donnelley, Martin, Morgan, Kaye S., Siu, Karen K. W., Fouras, Andreas, Farrow, Nigel R., Carnibella, Richard P., Parsons, David W.

“…To assess potential therapies for respiratory diseases in which mucociliary transit (MCT) is impaired, such as cystic fibrosis and primary ciliary dyskinesia,…”
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Feasibility study of propagation-based phase-contrast X-ray lung imaging on the Imaging and Medical beamline at the Australian Synchrotron by Murrie, Rhiannon P., Stevenson, Andrew W., Morgan, Kaye S., Fouras, Andreas, Paganin, David M., Siu, Karen K. W.

“…Propagation‐based phase‐contrast X‐ray imaging (PB‐PCXI) using synchrotron radiation has achieved high‐resolution imaging of the lungs of small animals both in…”
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X-ray Velocimetry and Haemodynamic Forces Within a Stenosed Femoral Model at Physiological Flow Rates by Jamison, R. Aidan, Dubsky, Stephen, Siu, Karen K. W., Hourigan, Kerry, Fouras, Andreas

“…High resolution in vivo velocity measurements within the cardiovascular system are essential for accurate calculation of vessel wall shear stress, a highly…”
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Measuring airway surface liquid depth in ex vivo mouse airways by x-ray imaging for the assessment of cystic fibrosis airway therapies by Morgan, Kaye S, Donnelley, Martin, Paganin, David M, Fouras, Andreas, Yagi, Naoto, Suzuki, Yoshio, Takeuchi, Akihisa, Uesugi, Kentaro, Boucher, Richard C, Parsons, David W, Siu, Karen K W

“…In the airways of those with cystic fibrosis (CF), the leading pathophysiological hypothesis is that an ion channel defect results in a relative decrease in…”
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Variability of in vivo fluid dose distribution in mouse airways is visualized by high-speed synchrotron X-ray imaging by Donnelley, Martin, Morgan, Kaye S, Siu, Karen K W, Parsons, David W

“…The manner in which fluid instillations into mouse nose and lung distribute through the airways is poorly understood. Many agents are delivered in this way for…”
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