Search Results - "Sisti, Flávia Malvestio"
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Caffeic acid phenethyl ester (CAPE) protects PC12 cells from MPP+ toxicity by inducing the expression of neuron-typical proteins
Published in Neurotoxicology (Park Forest South) (01-12-2014)“…•Total inhibition of neuritogenesis is an early step in the neurotoxicity of MPP+.•CAPE induces neuritogenesis and synaptogenesis in non-NGF-stimulated PC12…”
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Doxycycline inhibits dopaminergic neurodegeneration through upregulation of axonal and synaptic proteins
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2023)“…Doxycycline (DOX) is a widely used antibiotic that is able to cross the blood–brain barrier. Several studies have shown its neuroprotective effect against…”
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The Neurotrophic-Like Effect of Carvacrol: Perspective for Axonal and Synaptic Regeneration
Published in Neurotoxicity research (01-06-2021)“…Carvacrol (CARV) is a phytochemical widely used as flavoring, preservative, and fragrance in food and cosmetic industries. CARV is able to cross the…”
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The antibiotic doxycycline mimics the NGF signaling in PC12 cells: A relevant mechanism for neuroprotection
Published in Chemico-biological interactions (25-05-2021)“…Doxycycline has been used as antibiotic since the 1960s. Recently, studies have shown that doxycycline is neuroprotective in models of neurodegenerative…”
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The neuroprotection of cannabidiol against MPP+-induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease
Published in Toxicology in vitro (25-12-2015)“…Cannabidiol (CBD) is a non-psychoactive constituent of Cannabis sativa with potential to treat neurodegenerative diseases. Its neuroprotection has been mainly…”
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The cannabinoid beta-caryophyllene (BCP) induces neuritogenesis in PC12 cells by a cannabinoid-receptor-independent mechanism
Published in Chemico-biological interactions (05-01-2017)“…Beta-caryophyllene (BCP) is a phytocannabinoid whose neuroprotective activity has been mainly associated with selective activation of cannabinoid-type-2 (CB2)…”
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Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity by Activating the AMPK/SIRT1, MAPK/Erk, and PI3k/Akt Signaling Pathways
Published in Neurotoxicity research (01-07-2019)“…Peripheral sensory neuropathy (PSN) is a well-known side effect of cisplatin characterized by axonal damage. In the early stage of neurotoxicity, cisplatin…”
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