Search Results - "Sis, B."

Understanding the Causes of Kidney Transplant Failure: The Dominant Role of Antibody‐Mediated Rejection and Nonadherence by Sellarés, J., de Freitas, D. G., Mengel, M., Reeve, J., Einecke, G., Sis, B., Hidalgo, L. G., Famulski, K., Matas, A., Halloran, P. F.

“…We prospectively studied kidney transplants that progressed to failure after a biopsy for clinical indications, aiming to assign a cause to every failure. We…”
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Antibody‐Mediated Microcirculation Injury Is the Major Cause of Late Kidney Transplant Failure by Einecke, G., Sis, B., Reeve, J., Mengel, M., Campbell, P. M., Hidalgo, L. G., Kaplan, B., Halloran, P. F.

“…We studied the phenotype of late kidney graft failure in a prospective study of unselected kidney transplant biopsies taken for clinical indications. We…”
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Intragraft Donor‐Specific Antibody Detection: A New Test to Dichotomize HLA Alloantibodies Into High and Low Injurious Activity by Sis, B.

“…Intragraft antibody detection opens new avenues for research and clinical decision‐making. See article by Bachelet et al on page 2855…”
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Molecular Diagnosis of Antibody‐Mediated Rejection in Human Kidney Transplants by Sellarés, J., Reeve, J., Loupy, A., Mengel, M., Sis, B., Skene, A., de Freitas, D. G., Kreepala, C., Hidalgo, L. G., Famulski, K. S., Halloran, P. F.

“…Antibody‐mediated rejection is the major cause of kidney transplant failure, but the histology‐based diagnostic system misses most cases due to its requirement…”
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Banff 2011 Meeting Report: New Concepts in Antibody‐Mediated Rejection by Mengel, M., Sis, B., Haas, M., Colvin, R. B., Halloran, P. F., Racusen, L. C., Solez, K., Cendales, L., Demetris, A. J., Drachenberg, C. B., Farver, C. F., Rodriguez, E. R., Wallace, W. D., Glotz, D.

“…The 11th Banff meeting was held in Paris, France, from June 5 to 10, 2011, with a focus on refining diagnostic criteria for antibody‐mediated rejection (ABMR)…”
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A New Diagnostic Algorithm for Antibody‐Mediated Microcirculation Inflammation in Kidney Transplants by Sis, B., Jhangri, G. S., Riopel, J., Chang, J., de Freitas, D. G., Hidalgo, L., Mengel, M., Matas, A., Halloran, P. F.

“…We studied the significance of microcirculation inflammation in kidney transplants, including 329 indication biopsies from 251 renal allograft recipients, who…”
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NK Cell Transcripts and NK Cells in Kidney Biopsies from Patients with Donor‐Specific Antibodies: Evidence for NK Cell Involvement in Antibody‐Mediated Rejection by Hidalgo, L. G., Sis, B., Sellares, J., Campbell, P. M., Mengel, M., Einecke, G., Chang, J., Halloran, P. F.

“…To explore the mechanisms of antibody‐mediated rejection (ABMR) in kidney transplants, we studied the transcripts expressed in clinically indicated biopsies…”
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Molecular Diagnosis of T Cell‐Mediated Rejection in Human Kidney Transplant Biopsies by Reeve, J., Sellarés, J., Mengel, M., Sis, B., Skene, A., Hidalgo, L., de Freitas, D. G., Famulski, K. S., Halloran, P. F.

“…Histologic diagnosis of T cell‐mediated rejection is flawed by subjective assessments, nonspecific lesions and arbitrary rules. This study developed a…”
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De Novo Donor‐Specific Antibody at the Time of Kidney Transplant Biopsy Associates with Microvascular Pathology and Late Graft Failure by Hidalgo, L. G., Campbell, P. M., Sis, B., Einecke, G., Mengel, M., Chang, J., Sellares, J., Reeve, J., Halloran, P. F.

“…We studied whether de novo donor‐specific antibodies (DSA) in sera from patients undergoing kidney transplant biopsies associate with specific histologic…”
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Transplant Glomerulopathy, Late Antibody‐Mediated Rejection and the ABCD Tetrad in Kidney Allograft Biopsies for Cause by Sis, B., Campbell, P. M., Mueller, T., Hunter, C., Cockfield, S. M., Cruz, J., Meng, C., Wishart, D., Solez, K., Halloran, P. F.

“…To define the relative frequency of phenotypes of transplant glomerulopathy, we retrospectively reviewed the findings in 1036 biopsies for clinical indications…”
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Interpreting NK Cell Transcripts Versus T Cell Transcripts in Renal Transplant Biopsies by Hidalgo, L. G., Sellares, J., Sis, B., Mengel, M., Chang, J., Halloran, P. F.

“…NK cell transcripts are increased in biopsies with antibody‐mediated rejection, whereas T cell transcripts are increased in T cell‐mediated rejection. However,…”
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Scoring Total Inflammation Is Superior to the Current Banff Inflammation Score in Predicting Outcome and the Degree of Molecular Disturbance in Renal Allografts by Mengel, M., Reeve, J., Bunnag, S., Einecke, G., Jhangri, G. S., Sis, B., Famulski, K., Guembes‐Hidalgo, L., Halloran, P. F.

“…Emerging molecular analysis can be used as an objective and independent assessment of histopathological scoring systems. We compared the existing Banff i‐score…”
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Microarray Analysis of Rejection in Human Kidney Transplants Using Pathogenesis‐Based Transcript Sets by Mueller, T. F., Einecke, G., Reeve, J., Sis, B., Mengel, M., Jhangri, G. S., Bunnag, S., Cruz, J., Wishart, D., Meng, C., Broderick, G., Kaplan, B., Halloran, P. F.

“…Microarrays offer potential for objective diagnosis and insights into pathogenesis of allograft rejection. We used mouse transplants to annotate…”
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Diagnosing Rejection in Renal Transplants: A Comparison of Molecular‐ and Histopathology‐Based Approaches by Reeve, J., Einecke, G., Mengel, M., Sis, B., Kayser, N., Kaplan, B., Halloran, P. F.

“…The transcriptome has considerable potential for improving biopsy diagnoses. However, to realize this potential the relationship between the molecular…”
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Molecular Correlates of Scarring in Kidney Transplants: The Emergence of Mast Cell Transcripts by Mengel, M., Reeve, J., Bunnag, S., Einecke, G., Sis, B., Mueller, T., Kaplan, B., Halloran, P. F.

“…In the Banff consensus, infiltrates in areas of scarring are ignored. This study aimed to characterize the molecular correlates and clinical significance of…”
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Efficient visible-light-driven photocatalytic removal of Acid Blue 92, E. coli, and S. aureus over Ag-AgCl nanoparticles-decorated bismuth sulfide microparticles by Dawi, E A, Padervand, M, Bargahi, A, Eftekhari-Sis, B, Bahrami, M K, Abdelkader, A

“…Abstract Bismuth sulfide particles were modified with Ag-AgCl nanoparticles to make a visible light active plasmonic photocatalyst. The powder x-ray…”
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SWOT Analysis of Banff: Strengths, Weaknesses, Opportunities and Threats of the International Banff Consensus Process and Classification System for Renal Allograft Pathology by Mengel, M., Sis, B., Halloran, P. F.

“…The Banff process defined the diagnostic histologic lesions for renal allograft rejection and created a standardized classification system where none had…”
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Molecular Assessment of Microcirculation Injury in Formalin‐Fixed Human Cardiac Allograft Biopsies With Antibody‐Mediated Rejection by Afzali, B., Chapman, E., Racapé, M., Adam, B., Bruneval, P., Gil, F., Kim, D., Hidalgo, L., Campbell, P., Sis, B., Duong Van Huyen, J. P., Mengel, M.

“…Precise diagnosis of antibody‐mediated rejection (AMR) in cardiac allograft endomyocardial biopsies (EMBs) remains challenging. This study assessed molecular…”
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An Integrated View of Molecular Changes, Histopathology and Outcomes in Kidney Transplants by Halloran, P. F., De Freitas, D. G., Einecke, G., Famulski, K. S., Hidalgo, L. G., Mengel, M., Reeve, J., Sellares, J., Sis, B.

“…Data‐driven approaches to deteriorating kidney transplants, incorporating histologic, molecular and HLA antibody findings, have created a new understanding of…”
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The Nature of Biopsies with “Borderline Rejection” and Prospects for Eliminating This Category by de Freitas, D. G., Sellarés, J., Mengel, M., Chang, J., Hidalgo, L. G., Famulski, K. S., Sis, B., Einecke, G., Halloran, P. F.

“…In kidney transplantation, many inflamed biopsies with changes insufficient to be called T‐cell‐mediated rejection (TCMR) are labeled “borderline”, leaving…”
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