Search Results - "Siroy, Alan"

Reactive Perforating Collagenosis in End-Stage Renal Disease: Not All that Itches Is Uremic Pruritis by Bejjanki, Harini, Siroy, Alan E., Koratala, Abhilash

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Metastatic Crohn disease: a rare cutaneous entity by Siroy, Alan, Wasman, Jay

“…Metastatic Crohn disease is a rare cutaneous disorder characterized by noncaseating, granulomatous skin lesions present at sites anatomically separate from the…”
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Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma by Siroy, Alan E, Boland, Genevieve M, Milton, Denái R, Roszik, Jason, Frankian, Silva, Malke, Jared, Haydu, Lauren, Prieto, Victor G, Tetzlaff, Michael, Ivan, Doina, Wang, Wei-Lien, Torres-Cabala, Carlos, Curry, Jonathan, Roy-Chowdhuri, Sinchita, Broaddus, Russell, Rashid, Asif, Stewart, John, Gershenwald, Jeffrey E, Amaria, Rodabe N, Patel, Sapna P, Papadopoulos, Nicholas E, Bedikian, Agop, Hwu, Wen-Jen, Hwu, Patrick, Diab, Adi, Woodman, Scott E, Aldape, Kenneth D, Luthra, Rajyalakshmi, Patel, Keyur P, Shaw, Kenna R, Mills, Gordon B, Mendelsohn, John, Meric-Bernstam, Funda, Kim, Kevin B, Routbort, Mark J, Lazar, Alexander J, Davies, Michael A

“…The management of melanoma has evolved owing to improved understanding of its molecular drivers. To augment the current understanding of the prevalence,…”
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Beyond BRAFV600: Clinical Mutation Panel Testing by Next-Generation Sequencing in Advanced Melanoma by Siroy, Alan E., Boland, Genevieve M., Milton, Denái R., Roszik, Jason, Frankian, Silva, Malke, Jared, Haydu, Lauren, Prieto, Victor G., Tetzlaff, Michael, Ivan, Doina, Wang, Wei-Lien, Torres-Cabala, Carlos, Curry, Jonathan, Roy-Chowdhuri, Sinchita, Broaddus, Russell, Rashid, Asif, Stewart, John, Gershenwald, Jeffrey E., Amaria, Rodabe N., Patel, Sapna P., Papadopoulos, Nicholas E., Bedikian, Agop, Hwu, Wen-Jen, Hwu, Patrick, Diab, Adi, Woodman, Scott E., Aldape, Kenneth D., Luthra, Rajyalakshmi, Patel, Keyur P., Shaw, Kenna R., Mills, Gordon B., Mendelsohn, John, Meric-Bernstam, Funda, Kim, Kevin B., Routbort, Mark J., Lazar, Alexander J., Davies, Michael A.

“…The management of melanoma has evolved owing to improved understanding of its molecular drivers. To augment the current understanding of the prevalence,…”
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Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set by Roszik, Jason, Haydu, Lauren E, Hess, Kenneth R, Oba, Junna, Joon, Aron Y, Siroy, Alan E, Karpinets, Tatiana V, Stingo, Francesco C, Baladandayuthapani, Veera, Tetzlaff, Michael T, Wargo, Jennifer A, Chen, Ken, Forget, Marie-Andrée, Haymaker, Cara L, Chen, Jie Qing, Meric-Bernstam, Funda, Eterovic, Agda K, Shaw, Kenna R, Mills, Gordon B, Gershenwald, Jeffrey E, Radvanyi, Laszlo G, Hwu, Patrick, Futreal, P Andrew, Gibbons, Don L, Lazar, Alexander J, Bernatchez, Chantale, Davies, Michael A, Woodman, Scott E

“…While clinical outcomes following immunotherapy have shown an association with tumor mutation load using whole exome sequencing (WES), its clinical…”
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MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer by Siroy, Alan, MD, Abdul-Karim, Fadi W., MD, Miedler, John, MD, Fong, Nancy, MD, Fu, Pingfu, PhD, Gilmore, Hannah, MD, Baar, Joseph, MD, PhD

“…Summary Triple-negative breast cancer comprises 10% to 15% of newly diagnosed breast cancer and lacks expression of the estrogen, progesterone, and human…”
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Granuloma Annulare Secondary to Vemurafenib Therapy for Lung Adenocarcinoma by Jenkinson, Helena A, Siroy, Alan E, Choksi, Adrienne

“…Numerous cutaneous manifestations have been associated with use of BRAF inhibitors, including two previously reported cases of granuloma annulare (GA)…”
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Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy by Mauzo, Shakuntala H, Tetzlaff, Michael T, Milton, Denái R, Siroy, Alan E, Nagarajan, Priyadharsini, Torres-Cabala, Carlos A, Ivan, Doina, Curry, Jonathan L, Hudgens, Courtney W, Wargo, Jennifer A, Sahin, Aysegul A, Pettaway, Curtis A, Prieto, Victor G, Aung, Phyu P

“…Extramammary Paget disease (EMPD) is a locally aggressive cutaneous malignancy that usually arises in anogenital or axillary skin. Immune checkpoint inhibitors…”
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Clinical Significance of BRAF V600E Mutational Status in Capsular Nevi of Sentinel Lymph Nodes in Patients with Primary Cutaneous Melanoma by Siroy, Alan E., MD,MPH, Aung, Phyu P., MD, PhD, Torres-Cabala, Carlos A., MD, Tetzlaff, Michael T., MD, PhD, Nagarajan, Priyadharsini, MD, PhD, Milton, Denái R., MS, Curry, Jonathan L., MD, Ivan, Doina, MD, Prieto, Victor G., MD, PhD

“…Capsular nevi (CN) are clusters of benign melanocytes situated in the capsule of lymph nodes and occur in up to 20% of lympadenectomy specimens. The molecular…”
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Acneiform eruptions associated with epidermal growth factor receptor–targeted chemotherapy by DeWitt, Christine A., MD, Siroy, Alan E., MPH, Stone, Stephen P., MD

“…A relatively newer class of chemotherapy agents, known as the epidermal growth factor receptor inhibitors (EGF-RIs), is being used to treat advanced stages of…”
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Tyrosine Kinase Inhibitor and Immune Checkpoint Inhibitor Responses in KIT-Mutant Metastatic Melanoma by McKean, Meredith, Oba, Junna, Ma, Junsheng, Roth, Katherine G, Wang, Wei-Lien, Macedo, Mariana P., Carapeto, Fernando C.L., Haydu, Lauren E., Siroy, Alan E., Vo, Phuong, Hong, David S., Eterovic, Agda K., Patel, Keyur Pravinchandra, Bassett, Roland L, Grimm, Elizabeth A., Lazar, Alexander J., Woodman, Scott E.

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Primary melanoma of the bladder by Siroy, Alan E, MacLennan, Gregory T

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Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression by Roszik, Jason, Wu, Chang-Jiun, Siroy, Alan E., Lazar, Alexander J., Davies, Michael A, Woodman, Scott E, Kwong, Lawrence N

“…Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists…”
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Abstract LB-330: Somatic copy number alterations at oncogenic loci show diverse correlations with gene expression by Roszik, Jason, Wu, Ching Jiun, Siroy, Alan E., Lazar, Alexander J., Davies, Michael A., Woodman, Scott, Kwong, Lawrence N.

“…Abstract Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon…”
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Clinicopathological features and clinical outcomes associated with TP53 and BRAF N on- V 600 mutations in cutaneous melanoma patients by Kim, Dae Won, Haydu, Lauren E, Joon, Aron Y, Bassett, Jr, Roland L, Siroy, Alan E, Tetzlaff, Michael T, Routbort, Mark J, Amaria, Rodabe N, Wargo, Jennifer A, McQuade, Jennifer L, Kemnade, Jan, Hwu, Patrick, Woodman, Scott E, Roszik, Jason, Kim, Kevin B, Gershenwald, Jeffrey E, Lazar, Alexander J, Davies, Michael A

“…BRAF , NRAS, TP53, and BRAF are among the most common mutations detected in non-acral cutaneous melanoma patients. Although several studies have identified…”
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Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon‐V600 mutations in cutaneous melanoma patients by Kim, Dae Won, Haydu, Lauren E., Joon, Aron Y., Bassett, Roland L., Siroy, Alan E., Tetzlaff, Michael T., Routbort, Mark J., Amaria, Rodabe N., Wargo, Jennifer A., McQuade, Jennifer L., Kemnade, Jan, Hwu, Patrick, Woodman, Scott E., Roszik, Jason, Kim, Kevin B., Gershenwald, Jeffrey E., Lazar, Alexander J., Davies, Michael A.

“…BACKGROUND BRAFV600, NRAS, TP53, and BRAFNon‐V600 are among the most common mutations detected in non‐acral cutaneous melanoma patients. Although several…”
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Anti-MDA-5 Dermatomyositis With Development of Drug-Mediated Necrolytic Skin Lesions by Case, Robert A., Patel, Vishal, Mejia-Otero, Carolina, Siroy, Alan E., Patel, Divya C.

“…A 59-year-old male presented with 1 month of progressive dyspnea, 30-lb weight loss, and skin changes on the digits of the hands. In the 4 weeks prior to…”
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Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations by Stockman, David L., Curry, Jonathan L., Torres-Cabala, Carlos A., Watson, Ian R., Siroy, Alan E., Bassett, Roland L., Zou, Lihua, Patel, Keyur P., Luthra, Rajyalakshmi, Davies, Michael A., Wargo, Jennifer A., Routbort, Mark A., Broaddus, Russell R., Prieto, Victor G., Lazar, Alexander J., Tetzlaff, Michael T.

“…Background SMARCB1 (INI1/BAF47/SNF5) encodes a part of a multiprotein complex that regulates gene expression through chromatin remodeling. SMARCB1 expression…”
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A novel approach: chest wall cyst excised by MIS by AlJamal, Yazan N., Siroy, Alan E., Farley, David R.

“…We present a 62-year-old male with a recurrent cyst in the left posterior chest. MRI demonstrated a fluid-filled cavity measuring 23 cm in length and 11 cm in…”
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Beyond BRAF V600 : Clinical Mutation Panel Testing by Next-Generation Sequencing in Advanced Melanoma by Siroy, Alan E., Boland, Genevieve M., Milton, Denái R., Roszik, Jason, Frankian, Silva, Malke, Jared, Haydu, Lauren, Prieto, Victor G., Tetzlaff, Michael, Ivan, Doina, Wang, Wei-Lien, Torres-Cabala, Carlos, Curry, Jonathan, Roy-Chowdhuri, Sinchita, Broaddus, Russell, Rashid, Asif, Stewart, John, Gershenwald, Jeffrey E., Amaria, Rodabe N., Patel, Sapna P., Papadopoulos, Nicholas E., Bedikian, Agop, Hwu, Wen-Jen, Hwu, Patrick, Diab, Adi, Woodman, Scott E., Aldape, Kenneth D., Luthra, Rajyalakshmi, Patel, Keyur P., Shaw, Kenna R., Mills, Gordon B., Mendelsohn, John, Meric-Bernstam, Funda, Kim, Kevin B., Routbort, Mark J., Lazar, Alexander J., Davies, Michael A.

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