Search Results - "Sirover, M A"

A Human Nuclear Uracil DNA Glycosylase is the 37-kDa Subunit of Glyceraldehyde-3-Phosphate Dehydrogenase by Meyer-Siegler, Katherine, Mauro, David J., Seal, Gita, Wurzer, James, deRiel, Jon K., Sirover, Michael A.

“…We have isolated and characterized a plasmid (pChug 20.1) that contains the cDNA of a nuclear uracil DNA glycosylase (UDG) gene isolated from normal human…”
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Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells by NASIMA RAHMAN MANSUR, MEYER-SIEGLER, K, WURZER, J. C, SIROVER, M. A

“…The cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH)/uracil DNA glycosylase (UDG) gene was examined in normal human cells. Steady…”
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New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase by Sirover, Michael A

“…Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical glycolytic protein examined for its pivotal role in energy production. It was also…”
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Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology by Sirover, Michael A.

“…The glycolytic protein glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) appeared to be an archtypical protein of limited excitement. However, independent…”
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New mechanism of action of the cancer chemotherapeutic agent 5-fluorouracil in human cells by Wurzer, J C, Tallarida, R J, Sirover, M A

“…5-Fluorouracil (5-FlUra), a cancer chemotherapeutic agent used in the treatment of colon, breast, ovarian and prostate cancer, is incorporated into DNA as a…”
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Mechanisms of excision of 5-fluorouracil by uracil DNA glycosylase in normal human cells by Mauro, D J, De Riel, J K, Tallarida, R J, Sirover, M A

“…Recent evidence indicates that 5-fluorouracil (5-FlUra) is incorporated into DNA and is removed by the DNA repair enzyme uracil DNA glycosylase. Synthetic…”
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Immunological Lesions in Human Uracil DNA Glycosylase: Association with Bloom Syndrome by Seal, Gita, Brech, Kilian, Karp, Seth J., Cool, Barbara L., Sirover, Michael A.

“…Three monoclonal antibodies that react with uracil DNA glycosylase of normal human placenta were tested to determine whether one of the antibodies could be…”
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Reduction of glyceraldehyde‐3‐phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts by Mazzola, Jennifer L., Sirover, Michael A.

“…New functions have been identified for glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) including its role in neurodegenerative disease and in apoptosis. GAPDH…”
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Physical Association of the Human Base-Excision Repair Enzyme Uracil DNA Glycosylase with the 70,000-Dalton Catalytic Subunit of DNA Polymerase α by Seal, Gita, Sirover, Michael A.

“…A monoclonal antibody prepared against a partially purified human uracil DNA glycosylase was found, on further purification of the enzyme, to be inactive…”
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Isolation and Characterization of the Human Uracil DNA Glycosylase Gene by Vollberg, Thomas M., Siegler, Katherine M., Cool, Barbara L., Sirover, Michael A.

“…A series of anti-human placental uracil DNA glycosylase monoclonal antibodies was used to screen a human placental cDNA library in phage λ gt11. Twenty-seven…”
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Proliferative dependent regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in human cells by Meyer-Siegler, K, Rahman-Mansur, N, Wurzer, J C, Sirover, M A

“…The relationship between the proliferative dependent expression of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH)/uracil DNA glycosylase (UDG) gene and…”
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Isolation and Characterization of Monoclonal Antibodies Directed against the DNA Repair Enzyme Uracil DNA Glycosylase from Human Placenta by Arenaz, Pablo, Sirover, Michael A.

“…A series of monoclonal antibodies has been prepared against the base excision repair enzyme uracil DNA glycosylase isolated from human placenta. Spleen cells…”
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Immunocytochemical localization of the base excision repair enzyme uracil DNA glycosylase in quiescent and proliferating normal human cells by COOL, B. L, SIROVER, M. A

“…The immunocytochemical localization of the base excision repair enzyme uracil DNA glycosylase was examined as a function of cell proliferation. Two…”
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Altered Temporal Expression of DNA Repair in Hypermutable Bloom's Syndrome Cells by Gupta, Pawan K., Sirover, Michael A.

“…The temporal regulation of DNA repair during synchronous cell proliferation was examined in normal human skin fibroblasts and in Bloom's syndrome skin…”
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Regulation of hypoxanthine DNA glycosylase in normal human and Bloom's syndrome fibroblasts by DEHAZYA, P, SIROVER, M. A

“…The regulation of the base excision repair enzyme hypoxanthine DNA glycosylase was examined in normal human skin fibroblasts (NHS) and fibroblasts from a…”
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On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase by Sirover, M A, Loeb, L A

“…The effect of metal activators on the fidelity of DNA synthesis has been examined. Using the DNA polymerase from avian myeloblastosis virus, the accuracy of…”
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Metal-Induced Infidelity during DNA Synthesis by Sirover, Michael A., Loeb, Lawrence A.

“…The effect of several divalent cations on the accuracy of DNA replication in vitro has been examined. Only Be2+altered the accuracy of DNA synthesis using…”
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Physical association of base excision repair enzymes with parental and replicating DNA in BHK-21 cells by LEE, K. A, SIROVER, M. A

“…The physical association of mammalian excision repair enzymes with DNA was examined as a function of cell proliferation. The molecular weight distribution of…”
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Regulation of DNA Repair in Serum-Stimulated Xeroderma Pigmentosum Cells by Gupta, Pawan K., Sirover, Michael A.

“…The regulation of DNA repair during serum stimulation of quiescent cells was examined in normal human cells, in fibroblasts from three xeroderma pigmentosum…”
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Biosynthesis of the human base excision repair enzyme uracil-DNA glycosylase by VOLLBERG, T. M, COOL, B. L, SIROVER, M. A

“…The biosynthesis of the human DNA repair enzyme uracil-DNA glycosylase has been characterized by the reaction of in vitro- and in vivo-produced protein with an…”
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