Search Results - "Sironi, Juan J"

STAT1-induced Apoptosis Is Mediated by Caspases 2, 3, and 7 by Sironi, Juan J., Ouchi, Toru

“…STAT1 (signal transducer and activator of transcription 1) has been implicated as a mediator of a variety of biological responses in response to stimulation by…”
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Quantitative peptidomics of Purkinje cell degeneration mice by Berezniuk, Iryna, Sironi, Juan J, Wardman, Jonathan, Pasek, Raymond C, Berbari, Nicolas F, Yoder, Bradley K, Fricker, Lloyd D

“…Cytosolic carboxypeptidase 1 (CCP1) is a metallopeptidase that removes C-terminal and side-chain glutamates from tubulin. The Purkinje cell degeneration (pcd)…”
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Cytosolic Carboxypeptidase 1 Is Involved in Processing α- and β-Tubulin by Berezniuk, Iryna, Vu, Hang T., Lyons, Peter J., Sironi, Juan J., Xiao, Hui, Burd, Berta, Setou, Mitsutoshi, Angeletti, Ruth H., Ikegami, Koji, Fricker, Lloyd D.

“…The Purkinje cell degeneration (pcd) mouse has a disruption in the gene encoding cytosolic carboxypeptidase 1 (CCP1). This study tested two proposed functions…”
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Cytosolic Carboxypeptidase 5 Removes α- and γ-Linked Glutamates from Tubulin by Berezniuk, Iryna, Lyons, Peter J., Sironi, Juan J., Xiao, Hui, Setou, Mitsutoshi, Angeletti, Ruth H., Ikegami, Koji, Fricker, Lloyd D.

“…Cytosolic carboxypeptidase 5 (CCP5) is a member of a subfamily of enzymes that cleave C-terminal and/or side chain amino acids from tubulin. CCP5 was proposed…”
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Ser-262 in human recombinant tau protein is a markedly more favorable site for phosphorylation by CaMKII than PKA or PhK by Sironi, Juan J, Yen, Shu-Hui, Gondal, Javed A, Wu, Qiongli, Grundke-Iqbal, Inge, Iqbal, Khalid

“…Several kinases have been shown to phosphorylate tau protein at Ser-262, an important site involved in the regulation of the binding of tau to microtubules. In…”
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The association of tubulin carboxypeptidase activity with microtubules in brain extracts is modulated by phosphorylation/dephosphorylation processes by Sironi, J J, Barra, H S, Arce, C A

“…Tubulin carboxypeptidase, the enzyme which releases the COOH terminal tyrosine from the alpha-chain of tubulin, remains associated with microtubules through…”
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Association of tubulin carboxypeptidase with microtubules in living cells by CONTIN, María A., SIRONI, Juan J., BARRA, Héctor S., ARCE, Carlos A.

“…Tubulin carboxypeptidase is the enzyme that releases the C-terminal tyrosine from α-tubulin, converting tyrosine-terminated (Tyr) to detyrosinated (Glu)…”
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Association of tubulin carboxypeptidase with microtubules in living cells by Contin, M A, Sironi, J J, Barra, H S, Arce, C A

“…Tubulin carboxypeptidase is the enzyme that releases the C-terminal tyrosine from alpha-tubulin, converting tyrosine-terminated (Tyr) to detyrosinated (Glu)…”
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Tubulin Carboxypeptidase Assay Based on the Action of the Enzyme on [14C]Tyrosinated Tubulin Bound to Nitrocellulose Membrane by Sironi, Juan J., Barra, Héctor S., Arce, Carlos A.

“…We have developed a method for the determination of tubulin carboxypeptidase activity which is based on the action of the enzyme on the substrate,…”
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Isolation of [alpha] and [beta] Brain Tubulin Subunits after Alkaline Treatment of the Protein by Beltramo, Dante M, Fernandez, Mariana Nuñez, Alonso, Alejandra Del; C, Sironi, Juan J, Barra, Héctor S

“…Issue Title: Dedicated to Dr. Eduardo Soto We demonstrate here that brain purified tubulin can be dissociated into α and β subunits at pH > 10 and that the…”
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Isolation of α and β brain tubulin subunits after alkaline treatment of the protein by BELTRAMO, D. M, NUNEZ FERNANDEZ, M, DEL C. ALONSO, A, SIRONI, J. J, BARRA, H. S

“…We demonstrate here that brain purified tubulin can be dissociated into alpha and beta subunits at pH > 10 and that the subunits can be separated by using the…”
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