Search Results - "Sironen, Reijo K."

Epidermal Growth Factor Activates Hyaluronan Synthase 2 in Epidermal Keratinocytes and Increases Pericellular and Intracellular Hyaluronan by Pienimäki, Juha-Pekka, Rilla, Kirsi, Fülöp, Csaba, Sironen, Reijo K., Karvinen, Susanna, Pasonen, Sanna, Lammi, Mikko J., Tammi, Raija, Hascall, Vincent C., Tammi, Markku I.

“…Hyaluronan is an abundant and rapidly turned over matrix molecule between the vital cell layers of the epidermis. In this study, epidermal growth factor (EGF)…”
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Prognostic significance of matrix metalloproteinase‐7 in epithelial ovarian cancer and its relation to β‐catenin expression by Sillanpää, Sari M., Anttila, Maarit A., Voutilainen, Kirsi A., Ropponen, Kirsi M., Sironen, Reijo K., Saarikoski, Serpo V., Kosma, Veli‐Matti

“…We investigated the expression and prognostic significance of matrix metalloproteinase (MMP) ‐7, its relation to β‐catenin expression and clinicopathological…”
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High hydrostatic pressure inhibits the biosynthesis of eukaryotic elongation factor-2 by Elo, Mika A., Karjalainen, Hannu M., Sironen, Reijo K., Valmu, Leena, Redpath, Nicholas T., Browne, Gareth J., Kalkkinen, Nisse, Helminen, Heikki J., Lammi, Mikko J.

“…High continuous hydrostatic pressure is known to inhibit the total cellular protein synthesis. In this study, our goal was to identify pressure‐regulated…”
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Hydrostatic pressure-induced changes in cellular protein synthesis by Lammi, Mikko J, Elo, Mika A, Sironen, Reijo K, Karjalainen, Hannu M, Kaarniranta, Kai, Helminen, Heikki J

“…Hydrostatic pressure is a well-known effector of cellular protein synthesis. High continuous hydrostatic pressure inhibits protein synthesis in general. It has…”
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Reticulon 4 in chondrocytic cells: barosensitivity and intracellular localization by Sironen, Reijo K, Karjalainen, Hannu M, Törrönen, Kari J, Elo, Mika A, Hyttinen, Mika M, Helminen, Heikki J, Lammi, Mikko J

“…Members of the reticulon gene family are endoplasmic reticulum (ER)-related proteins expressed in various human tissues, but their molecular functions are not…”
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cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure by Sironen, Reijo K, Karjalainen, Hannu M, Elo, Mika A, Kaarniranta, Kai, Törrönen, Kari, Takigawa, Masaharu, Helminen, Heikki J, Lammi, Mikko J

“…Hydrostatic pressure (HP) has a profound effect on cartilage metabolism in normal and pathological conditions, especially in weight-bearing areas of the…”
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High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis by Sironen, Reijo K, Karjalainen, Hannu M, Törrönen, Kari, Elo, Mika A, Kaarniranta, Kai, Takigawa, Masaharu, Helminen, Heikki J, Lammi, Mikko J

“…Hydrostatic pressure has a profound effect on cartilage tissue and chondrocyte metabolism. Depending on the type and magnitude of pressure various responses…”
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Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells by Kaarniranta, Kai, Ryhänen, Tuomas, Sironen, Reijo K., Suuronen, Tiina, Elo, Mika A., Karjalainen, Hannu M., Lammi, Mikko J., Teräsvirta, Markku, Uusitalo, Hannu, Salminen, Antero

“…Reversible protein phosphorylation regulates the biological activities of many human proteins involved in crucial cellular processes, e.g., protein–protein…”
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FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women by Figlioli, Gisella, Billaud, Amandine, Ahearn, Thomas U, Antonenkova, Natalia N, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blok, Marinus J, Bogdanova, Natalia V, Bonanni, Bernardo, Burwinkel, Barbara, Camp, Nicola J, Campbell, Archie, Castelao, Jose E, Cessna, Melissa H, Chanock, Stephen J, Czene, Kamila, Devilee, Peter, Dörk, Thilo, Engel, Christoph, Eriksson, Mikael, Fasching, Peter A, Figueroa, Jonine D, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, González-Neira, Anna, Grassmann, Felix, Guénel, Pascal, Gündert, Melanie, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Harrington, Patricia A, He, Wei, Hillemanns, Peter, Hollestelle, Antoinette, Hooning, Maartje J, Hoppe, Reiner, Howell, Anthony, Humphreys, Keith, Jager, Agnes, Jakubowska, Anna, Khusnutdinova, Elza K, Ko, Yon-Dschun, Kristensen, Vessela N, Lindblom, Annika, Lissowska, Jolanta, Lubiński, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Mavroudis, Dimitrios, Newman, William G, Obi, Nadia, Panayiotidis, Mihalis I, Rashid, Muhammad U, Rhenius, Valerie, Rookus, Matti A, Saloustros, Emmanouil, Sawyer, Elinor J, Schmutzler, Rita K, Shah, Mitul, Sironen, Reijo, Southey, Melissa C, Suvanto, Maija, Tollenaar, Rob A E M, Tomlinson, Ian, Truong, Thérèse, van der Kolk, Lizet E, van Veen, Elke M, Wappenschmidt, Barbara, Yang, Xiaohong R, Bolla, Manjeet K, Dennis, Joe, Dunning, Alison M, Easton, Douglas F, Lush, Michael, Michailidou, Kyriaki, Pharoah, Paul D P, Wang, Qin, Adank, Muriel A, Schmidt, Marjanka K, Andrulis, Irene L, Chang-Claude, Jenny, Nevanlinna, Heli, Chenevix-Trench, Georgia, Evans, D Gareth, Milne, Roger L, Radice, Paolo, Peterlongo, Paolo

“…Evidence from literature, including the BRIDGES study, indicates that germline protein truncating variants (PTVs) in FANCM confer moderately increased risk of…”
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Churg-Strauss syndrome manifested by appendicitis, cholecystitis and superficial micronodular liver lesions--an unusual clinicopathological presentation by Sironen, R K, Seppä, A, Kosma, V M, Kuopio, T

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Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study by Karjalainen, Hannu M, Sironen, Reijo K, Elo, Mika A, Kaarniranta, Kai, Takigawa, Masaharu, Helminen, Heikki J, Lammi, Mikko J

“…Mechanical forces have a profound effect on cartilage tissue and chondrocyte metabolism. Strenuous loading inhibits the cellular metabolism, while optimal…”
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Differential regulation of stress proteins by high hydrostatic pressure, heat shock, and unbalanced calcium homeostasis in chondrocytic cells by Elo, Mika A., Sironen, Reijo K., Kaarniranta, Kai, Auriola, Seppo, Helminen, Heikki J., Lammi, Mikko J.

“…High hydrostatic pressure (HP) has recently been shown to increase cellular heat shock protein 70 (Hsp70) level in a specific way that does not involve…”
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Stress responses of mammalian cells to high hydrostatic pressure by Kaarniranta, Kai, Elo, Mika A, Sironen, Reijo K, Karjalainen, Hannu M, Helminen, Heikki J, Lammi, Mikko J

“…High hydrostatic pressure causes stress response in many types of mammalian cells. We have previously shown that an accumulation of heat shock protein 70…”
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Specific induction of heat shock protein 90beta by high hydrostatic pressure by Elo, Mika A, Sironen, Reijo K, Karjalainen, Hannu M, Kaarniranta, Kai, Helminen, Heikki J, Lammi, Mikko J

“…In chondrocytes, a low-amplitude intermittent hydrostatic pressure induces production of extracellular matrix molecules, while high hydrostatic pressure…”
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