Search Results - "Sirma, Hüseyin"

Proteasome-Dependent Degradation of Daxx by the Viral E1B-55K Protein in Human Adenovirus-Infected Cells by Schreiner, Sabrina, Wimmer, Peter, Sirma, Hüseyin, Everett, Roger D, Blanchette, Paola, Groitl, Peter, Dobner, Thomas

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Replication of ICP0-Null Mutant Herpes Simplex Virus Type 1 Is Restricted by both PML and Sp100 by Everett, Roger D, Parada, Carlos, Gripon, Philippe, Sirma, Hüseyin, Orr, Anne

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Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness by Kari, Vijayalakshmi, Mansour, Wael Yassin, Raul, Sanjay Kumar, Baumgart, Simon J, Mund, Andreas, Grade, Marian, Sirma, Hüseyin, Simon, Ronald, Will, Hans, Dobbelstein, Matthias, Dikomey, Ekkehard, Johnsen, Steven A

“…The CHD1 gene, encoding the chromo‐domain helicase DNA‐binding protein‐1, is one of the most frequently deleted genes in prostate cancer. Here, we examined the…”
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ERG Status Is Unrelated to PSA Recurrence in Radically Operated Prostate Cancer in the Absence of Antihormonal Therapy by MINNER, Sarah, ENODIEN, Malaika, BRASE, Jan C, LIU, Alvin Y, SCHLÜTER, Hartmut, PANTEL, Klaus, SCHUMACHER, Udo, BOKEMEYER, Carsten, STEUBER, Thomas, GRAEFEN, Markus, SAUTER, Guido, SCHLOMM, Thorsten, SIRMA, Hüseyin, LUEBKE, Andreas M, KROHN, Antje, MAYER, Pascale S, SIMON, Ronald, TENNSTEDT, Pierre, MÜLLER, Julia, SCHOLZ, Laura

“…About 50% of prostate cancers have TMPRSS2-ERG fusions with concurrent ERG overexpression. The aim of this study was to determine whether clinical differences…”
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Loss of pSer2448‐mTOR expression is linked to adverse prognosis and tumor progression in ERG‐fusion‐positive cancers by Müller, Julia, Ehlers, Arne, Burkhardt, Lia, Sirma, Hüseyin, Steuber, Thomas, Graefen, Markus, Sauter, Guido, Minner, Sarah, Simon, Ronald, Schlomm, Thorsten, Michl, Uwe

“…Prevalence and clinical significance of mammalian target of rapamycin (mTOR) phosphorylation at the serine 2448 is disputed in prostate cancer. A tissue…”
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PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication by Cuchet, Delphine, Sykes, Amanda, Nicolas, Armel, Orr, Anne, Murray, Jill, Sirma, Hüseyin, Heeren, Joerg, Bartelt, Alexander, Everett, Roger D

“…Intrinsic antiviral resistance mediated by constitutively expressed cellular proteins is one arm of defence against virus infection. Promyelocytic leukaemia…”
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TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling by Brase, Jan C, Johannes, Marc, Mannsperger, Heiko, Fälth, Maria, Metzger, Jennifer, Kacprzyk, Lukasz A, Andrasiuk, Tatjana, Gade, Stephan, Meister, Michael, Sirma, Hüseyin, Sauter, Guido, Simon, Ronald, Schlomm, Thorsten, Beissbarth, Tim, Korf, Ulrike, Kuner, Ruprecht, Sültmann, Holger

“…TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion…”
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CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo by Oh-Hohenhorst, Su Jung, Tilki, Derya, Ahlers, Ann-Kristin, Suling, Anna, Hahn, Oliver, Tennstedt, Pierre, Matuszcak, Christiane, Maar, Hanna, Labitzky, Vera, Hanika, Sandra, Starzonek, Sarah, Baumgart, Simon, Johnsen, Steven A., Kluth, Martina, Sirma, Hüseyin, Simon, Ronald, Sauter, Guido, Huland, Hartwig, Schumacher, Udo, Lange, Tobias

“…The outcome of prostate cancer (PCa) patients is highly variable and depends on whether or not distant metastases occur. Multiple chromosomal deletions have…”
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Duck Hepatitis B Virus Requires Cholesterol for Endosomal Escape during Virus Entry by FUNK, Anneke, MHAMDI, Mouna, HOHENBERG, Heinz, HEEREN, Jörg, REIMER, Rudolph, LAMBERT, Carsten, PRANGE, Reinhild, SIRMA, Hiiseyin

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High lysophosphatidylcholine acyltransferase 1 expression independently predicts high risk for biochemical recurrence in prostate cancers by Grupp, Katharina, Sanader, Stella, Sirma, Hüseyin, Simon, Ronald, Koop, Christina, Prien, Kristina, Hube-Magg, Claudia, Salomon, Georg, Graefen, Markus, Heinzer, Hans, Minner, Sarah, Izbicki, Jakob R., Sauter, Guido, Schlomm, Thorsten, Tsourlakis, Maria Christina

“…Lysophosphatidylcholine acyltransferase 1 (LPCAT1) has been suggested to play a role in cancer. To assess its role in prostate cancer, LPCAT1 expression was…”
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Nuclear Translocation of Papillomavirus Minor Capsid Protein L2 Requires Hsc70 by Florin, Luise, Becker, Katrin A, Sapp, Cornelia, Lambert, Carsten, Sirma, Hüseyin, Müller, Martin, Streeck, Rolf E, Sapp, Martin

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Matrix conditions and KLF2-dependent induction of heme oxygenase-1 modulate inhibition of HCV replication by fluvastatin by Wuestenberg, Andrea, Kah, Janine, Singethan, Katrin, Sirma, Hüseyin, Keller, Amelie Dorothea, Rosal, Sergio René Perez, Schrader, Jörg, Loscher, Christine, Volz, Tassilo, Bartenschlager, Ralf, Lohmann, Volker, Protzer, Ulrike, Dandri, Maura, Lohse, Ansgar W, Tiegs, Gisa, Sass, Gabriele

“…HMG-CoA-reductase-inhibitors (statins) have been shown to interfere with HCV replication in vitro. We investigated the mechanism, requirements and contribution…”
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Selection and Counterselection of the rtI233V Adefovir Resistance Mutation during Antiviral Therapy by Schildgen, Oliver, Olotu, Cynthia, Funk, Anneke, Zöllner, Bernhard, Helm, Martin, Rockstroh, Jürgen Kurt, Sirma, Hüseyin

“…Recently, we reported on three patients with chronic hepatitis B virus (HBV) infection for whom adefovir (ADF) therapy virologically failed, most likely due to…”
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Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx by SIRMA, H, GIANNINI, C, POUSSIN, K, PATERLINI, P, KREMSDORF, D, BRECHOT, C

“…Chronic infection by HBV is the leading cause of hepatocellular carcinoma in man. Several lines of evidence suggest that the viral transactivator HBx plays a…”
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Overexpression of the chromatin remodeler death-domain–associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence by Tsourlakis, Maria Christina, MD, Schoop, Michael, PhD, Plass, Christoph, PhD, Huland, Hartwig, MD, Graefen, Markus, MD, Steuber, Thomas, MD, Schlomm, Thorsten, MD, Simon, Ronald, PhD, Sauter, Guido, MD, Sirma, Hüseyin, MD, Minner, Sarah, MD

“…Summary Molecular markers reliably predicting the aggressiveness of prostate cancer are currently lacking. Death-domain–associated protein (DAXX) has been…”
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Intratumoral heterogeneity of KRAS mutation is rare in non-small-cell lung cancer by Alsdorf, Winfried H., Clauditz, Till S., Hoenig, Tobias, Quaas, Alexander, Sirma, Hüseyin, Koenig, Alexandra M., Izbicki, Jakob, Sauter, Guido, Marx, Andreas H., Grob, Tobias J.

“…Several lines of evidence indicate that mutational activation of KRAS is an early event in the carcinogenesis of non-small cell lung cancer (NSCLC)…”
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Itinerary of Hepatitis B Viruses: Delineation of Restriction Points Critical for Infectious Entry by FUNK, Anneke, MHAMDI, Mouna, LI LIN, WILL, Hans, SIRMA, Hüseyin

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Identification of a Structural Motif Crucial for Infectivity of Hepatitis B Viruses by Stoeckl, Lars, Funk, Anneke, Kopitzki, Ariane, Brandenburg, Boerries, Oess, Stefanie, Will, Hans, Sirma, Hüseyin, Hildt, Eberhard

“…Infectious entry of hepatitis B viruses (HBV) has nonconventional facets. Here we analyzed whether a cell-permeable peptide [translocation motif (TLM)]…”
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New Hepatitis B Virus of Cranes That Has an Unexpected Broad Host Range by Prassolov, Alexej, Hohenberg, Heinz, Kalinina, Tatyana, Schneider, Carola, Cova, Lucyna, Krone, Oliver, Frölich, Kai, Will, Hans, Sirma, Hüseyin

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Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression by MÖLLER, Andreas, SIRMA, Hüseyin, HOFMANN, Thomas G, STAEGE, Hannah, GRESKO, Ekaterina, LÜDI, Katharina Schmid, KLIMCZAK, Elisabeth, DRÖGE, Wulf, WILL, Hans, SCHMITZ, M. Lienhard

“…HIPK2 shows overlapping localization with p53 in promyelocytic leukemia (PML) nuclear bodies (PML-NBs) and functionally interacts with p53 to increase gene…”
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