Search Results - "Sirajuddin, Minhajuddin"

Regulation of microtubule motors by tubulin isotypes and post-translational modifications by Sirajuddin, Minhajuddin, Rice, Luke M., Vale, Ronald D.

“…The ‘tubulin-code’ hypothesis proposes that different tubulin genes or post-translational modifications (PTMs), which mainly confer variation in the…”
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Structural insights into actin filament recognition by commonly used cellular actin markers by Kumari, Archana, Kesarwani, Shubham, Javoor, Manjunath G, Vinothkumar, Kutti R, Sirajuddin, Minhajuddin

“…Cellular studies of filamentous actin (F‐actin) processes commonly utilize fluorescent versions of toxins, peptides, and proteins that bind actin. While the…”
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Structural insight into filament formation by mammalian septins by Wittinghofer, Alfred, Hauer, Florian, Sirajuddin, Minhajuddin, Macara, Ian G, Stark, Holger, Farkasovsky, Marian, Kühlmann, Dorothee, Weyand, Michael

“…Septins are GTP-binding proteins that assemble into homo- and hetero-oligomers and filaments. Although they have key roles in various cellular processes,…”
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Lysate-based pipeline to characterize microtubule-associated proteins uncovers unique microtubule behaviours by Jijumon, A. S., Bodakuntla, Satish, Genova, Mariya, Bangera, Mamata, Sackett, Violet, Besse, Laetitia, Maksut, Fatlinda, Henriot, Veronique, Magiera, Maria M., Sirajuddin, Minhajuddin, Janke, Carsten

“…The microtubule cytoskeleton forms complex macromolecular assemblies with a range of microtubule-associated proteins (MAPs) that have fundamental roles in cell…”
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Cardiomyocyte orientation recovery at micrometer scale reveals long-axis fiber continuum in heart walls by Dileep, Drisya, Syed, Tabish A, Sloan, Tyler Fw, Dhandapany, Perundurai S, Siddiqi, Kaleem, Sirajuddin, Minhajuddin

“…Coordinated cardiomyocyte contraction drives the mammalian heart to beat and circulate blood. No consensus model of cardiomyocyte geometrical arrangement…”
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GTP-induced conformational changes in septins and implications for function by Sirajuddin, Minhajuddin, Farkasovsky, Marian, Zent, Eldar, Wittinghofer, Alfred

“…Septins constitute a group of GTP-binding proteins involved in cytokinesis and other essential cellular functions. They form heterooligomeric complexes that…”
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Genetically encoded live-cell sensor for tyrosinated microtubules by Kesarwani, Shubham, Lama, Prakash, Chandra, Anchal, Reddy, P Purushotam, Jijumon, A S, Bodakuntla, Satish, Rao, Balaji M, Janke, Carsten, Das, Ranabir, Sirajuddin, Minhajuddin

“…Microtubule cytoskeleton exists in various biochemical forms in different cells due to tubulin posttranslational modifications (PTMs). Tubulin PTMs are known…”
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De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy by Esmaeeli Nieh, Sahar, Madou, Maura R. Z., Sirajuddin, Minhajuddin, Fregeau, Brieana, McKnight, Dianalee, Lexa, Katrina, Strober, Jonathan, Spaeth, Christine, Hallinan, Barbara E., Smaoui, Nizar, Pappas, John G., Burrow, Thomas A., McDonald, Marie T., Latibashvili, Mariam, Leshinsky‐Silver, Esther, Lev, Dorit, Blumkin, Luba, Vale, Ronald D., Barkovich, Anthony James, Sherr, Elliott H.

“…Objective To determine the cause and course of a novel syndrome with progressive encephalopathy and brain atrophy in children. Methods Clinical whole‐exome…”
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Thermodynamic effects of proline introduction on protein stability by Prajapati, Ravindra Singh, Das, Mili, Sreeramulu, Sridhar, Sirajuddin, Minhajuddin, Srinivasan, Sankaranarayanan, Krishnamurthy, Vaishnavi, Ranjani, Ranganathan, Ramakrishnan, C., Varadarajan, Raghavan

“…The amino acid Pro is more rigid than other naturally occurring amino acids and, in proteins, lacks an amide hydrogen. To understand the structural and…”
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De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy by Esmaeeli Nieh, Sahar, Madou, Maura R. Z., Sirajuddin, Minhajuddin, Fregeau, Brieana, McKnight, Dianalee, Lexa, Katrina, Strober, Jonathan, Spaeth, Christine, Hallinan, Barbara E., Smaoui, Nizar, Pappas, John G., Burrow, Thomas A., McDonald, Marie T., Latibashvili, Mariam, Leshinsky‐Silver, Esther, Lev, Dorit, Blumkin, Luba, Vale, Ronald D., Barkovich, Anthony James, Sherr, Elliott H.

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Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility by McKenney, Richard J, Huynh, Walter, Vale, Ronald D, Sirajuddin, Minhajuddin

“…Post‐translational modifications (PTMs) of α/β‐tubulin are believed to regulate interactions with microtubule‐binding proteins. A well‐characterized PTM…”
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It takes two to tango: regulation of G proteins by dimerization by Wittinghofer, Alfred, Gasper, Raphael, Meyer, Simon, Gotthardt, Katja, Sirajuddin, Minhajuddin

“…Guanine nucleotide-binding (G) proteins are regulated by GTPase-activating proteins and guanine nucleotide-exchange factors. Another class of G proteins is…”
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Nanobody derived using a peptide epitope from the spike protein receptor-binding motif inhibits entry of SARS-CoV-2 variants by Mendon, Nivya, Ganie, Rayees A., Kesarwani, Shubham, Dileep, Drisya, Sasi, Sarika, Lama, Prakash, Chandra, Anchal, Sirajuddin, Minhajuddin

“…The emergence of new escape mutants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has escalated its penetration among the human…”
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Cryo-EM research in India by Shukla, Arun K, Banerjee, Manidipa, Singh, Appu K, Penmatsa, Aravind, Dutta, Somnath, Anand, Ruchi, Sirajuddin, Minhajuddin, Srivastava, Shanti Swaroop

“…To celebrate the 50th anniversary of Cell Press and the Cell special issue focusing on structural biology, we want to highlight the rapid progress of cryo-EM…”
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Sequence diversity of tubulin isotypes in regulation of the mitochondrial voltage-dependent anion channel by Rostovtseva, Tatiana K., Gurnev, Philip A., Hoogerheide, David P., Rovini, Amandine, Sirajuddin, Minhajuddin, Bezrukov, Sergey M.

“…The microtubule protein tubulin is a heterodimer comprising α/β subunits, in which each subunit features multiple isotypes in vertebrates. For example, seven…”
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Tyrosination of [alpha]-tubulin controls the initiation of processive dynein-dynactin motility by McKenney, Richard J, Huynh, Walter, Vale, Ronald D, Sirajuddin, Minhajuddin

“…Post-translational modifications (PTMs) of [alpha]/[beta]-tubulin are believed to regulate interactions with microtubule-binding proteins. A well-characterized…”
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Regulation of microtubule motors by tubulin isotypes and posttranslational modifications by Sirajuddin, Minhajuddin, Rice, Luke M., Vale, Ronald D.

“…The ‘tubulin-code’ hypothesis proposes that different tubulin genes or posttranslational modifications (PTMs), which mainly confer variation in the…”
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Using Engineered Recombinant Tubulin Sotypes to Study VDAC Regulation by Gurnev, Philip A., Hoogerheide, David P., Sirajuddin, Minhajuddin, Bergdoll, Lucie, Abramson, Jeff, Rostovtseva, Tatiana K., Bezrukov, Sergey M.

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Contribution of Cation−π Interactions to Protein Stability by Prajapati, Ravindra S, Sirajuddin, Minhajuddin, Durani, Venuka, Sreeramulu, Sridhar, Varadarajan, Raghavan

“…Calculations predict that cation−π interactions make an important contribution to protein stability. While there have been some attempts to experimentally…”
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