The effect of artificial sweeteners on body weight of mice

The effect of artificial sweeteners on body weight of mice

Artificial Sweeteners (AS) are synthetic sugar substitutes that have sweetening potency hundreds of times more than the table sugar (sucrose). Artificial sweeteners are regarded as attractive alternatives to sugar as they add no calories to food intake. There are many hypotheses suggesting that AS m...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Biological Research Vol. 93; no. 2
Main Authors: Ali, Iyad, Shraim, Naser, Atrash, Wafaa’, Sirafi, Aisha, Abadi, Huda
Format: Journal Article
Language:English
Published: Pavia PAGEPress Publications 01-01-2020
Subjects:
Animal behavior
Appetite
Artificial Sweeteners
Body weight
Body weight gain
Calories
Cyproheptadine
Energy balance
Fluid intake
Food
Food consumption
Food intake
mice
Oral administration
Sucrose
Sugar
Sweeteners
Thymus vulgaris
Zingiber officinale
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Artificial Sweeteners (AS) are synthetic sugar substitutes that have sweetening potency hundreds of times more than the table sugar (sucrose). Artificial sweeteners are regarded as attractive alternatives to sugar as they add no calories to food intake. There are many hypotheses suggesting that AS may enhance appetite and cause weight gain. The aim of this study was to evaluate the effect of AS on food intake, fluid intake and body weight of mice. Acceptable daily intakes of AS solutions were administered orally to different set of mice for four weeks. The body weight, food consumption and fluid intake were measured. At the same time, the effect of Zingiber officinale extracts (natural appetite suppressor), Thymus vulgaris extracts (natural appetite inducer) and cyproheptadine (an appetite stimulant drug) on body weight of mice was evaluated. Artificial sweeteners consumption cause insignificant changes in body weight (p>0.05). However, the mean consumption of food and solutions varies significantly for some groups. The consumption of AS has no significant effect on body weight and may contribute to weight maintenance and energy balance as substitutes to high caloric sugar
ISSN:1826-8838
2284-0230
DOI:10.4081/jbr.2020.8783