Search Results - "Sips, Adrienne J. A. M"

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration by De Jong, Wim H, Hagens, Werner I, Krystek, Petra, Burger, Marina C, Sips, Adriënne J.A.M, Geertsma, Robert E

“…Abstract A kinetic study was performed to determine the influence of particle size on the in vivo tissue distribution of spherical-shaped gold nanoparticles in…”
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The oral bioavailability of nitrate from nitrate-rich vegetables in humans by van Velzen, Agnes G., Sips, Adrienne J.A.M., Schothorst, Ronald C., Lambers, Annette C., Meulenbelt, Jan

“…High dietary nitrate intake may pose a risk to human health. Since up to 80–85% of dietary nitrate intake comes from vegetables, the aim of this study was to…”
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Bioavailability of sodium nitrite from an aqueous solution in healthy adults by Hunault, Claudine C., van Velzen, Agnes G., Sips, Adrienne J.A.M., Schothorst, Ronald C., Meulenbelt, Jan

“…Nitrate intake in humans is high through intake of vegetables such as beets, lettuce, and spinach. Nitrate itself is a compound of low toxicity but its…”
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Comparison of five in vitro digestion models to in vivo experimental results: Lead bioaccessibility in the human gastrointestinal tract by Van de Wiele, Tom R., Oomen, Agnes G., Wragg, Joanna, Cave, Mark, Minekus, Mans, Hack, Alfons, Cornelis, Christa, Rompelberg, Cathy J.M., De Zwart, Loeckie L., Klinck, Ben, Van Wijnen, Joop, Verstraete, Willy, Sips, Adriënne J.A.M.

“…This paper presents a multi-laboratory comparison study of in vitro models assessing bioaccessibility of soil-bound lead in the human gastrointestinal tract…”
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Comparison of Five In Vitro Digestion Models To Study the Bioaccessibility of Soil Contaminants by Oomen, Agnes G, Hack, Alfons, Minekus, Mans, Zeijdner, Evelijn, Cornelis, Christa, Schoeters, Greet, Verstraete, Willy, Van de Wiele, Tom, Wragg, Joanna, Rompelberg, Cathy J. M, Sips, Adriënne J. A. M, Van Wijnen, Joop H

“…Soil ingestion can be a major exposure route for humans to many immobile soil contaminants. Exposure to soil contaminants can be overestimated if oral…”
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Considerations for Safe Innovation: The Case of Graphene by Park, Margriet V.D.Z, Bleeker, Eric A.J, Brand, Walter, Cassee, Flemming R, van Elk, Merel, Gosens, Ilse, de Jong, Wim H, Meesters, Johannes A.J, Peijnenburg, Willie J.G.M, Quik, Joris T.K, Vandebriel, Rob J, Sips, Adriënne J.A.M

“…The terms “Safe innovation” and “Safe­(r)-by-design” are currently popular in the field of nanotechnology. These terms are used to describe approaches that…”
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Towards a nanospecific approach for risk assessment by Dekkers, Susan, Oomen, Agnes G., Bleeker, Eric A.J., Vandebriel, Rob J., Micheletti, Christian, Cabellos, Joan, Janer, Gemma, Fuentes, Natalia, Vázquez-Campos, Socorro, Borges, Teresa, Silva, Maria João, Prina-Mello, Adriele, Movia, Dania, Nesslany, Fabrice, Ribeiro, Ana R., Leite, Paulo Emílio, Groenewold, Monique, Cassee, Flemming R., Sips, Adrienne J.A.M., Dijkzeul, Aart, van Teunenbroek, Tom, Wijnhoven, Susan W.P.

“…In the current paper, a new strategy for risk assessment of nanomaterials is described, which builds upon previous project outcomes and is developed within the…”
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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing by Marx, Uwe, Andersson, Tommy B, Bahinski, Anthony, Beilmann, Mario, Beken, Sonja, Cassee, Flemming R, Cirit, Murat, Daneshian, Mardas, Fitzpatrick, Susan, Frey, Olivier, Gaertner, Claudia, Giese, Christoph, Griffith, Linda, Hartung, Thomas, Heringa, Minne B, Hoeng, Julia, de Jong, Wim H, Kojima, Hajime, Kuehnl, Jochen, Leist, Marcel, Luch, Andreas, Maschmeyer, Ilka, Sakharov, Dmitry, Sips, Adrienne J A M, Steger-Hartmann, Thomas, Tagle, Danilo A, Tonevitsky, Alexander, Tralau, Tewes, Tsyb, Sergej, van de Stolpe, Anja, Vandebriel, Rob, Vulto, Paul, Wang, Jufeng, Wiest, Joachim, Rodenburg, Marleen, Roth, Adrian

“…The recent advent of microphysiological systems - microfluidic biomimetic devices that aspire to emulate the biology of human tissues, organs and circulation…”
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A Methodological Safe-by-Design Approach for the Development of Nanomedicines by Schmutz, Mélanie, Borges, Olga, Jesus, Sandra, Borchard, Gerrit, Perale, Giuseppe, Zinn, Manfred, Sips, Ädrienne A J A M, Soeteman-Hernandez, Lya G, Wick, Peter, Som, Claudia

“…Safe-by-Design (SbD) concepts foresee the risk identification and reduction as well as uncertainties regarding human health and environmental safety in early…”
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Review of health safety aspects of nanotechnologies in food production by Bouwmeester, Hans, Dekkers, Susan, Noordam, Maryvon Y., Hagens, Werner I., Bulder, Astrid S., de Heer, Cees, ten Voorde, Sandra E.C.G., Wijnhoven, Susan W.P., Marvin, Hans J.P., Sips, Adriënne J.A.M.

“…Due to new, previously unknown, properties attributed to engineered nanoparticles many new products are introduced in the agro-food area. Nanotechnologies…”
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Mobilization of PCBs and Lindane from Soil during in Vitro Digestion and Their Distribution among Bile Salt Micelles and Proteins of Human Digestive Fluid and the Soil by Oomen, Agnes G, Sips, Adrienne J. A. M, Groten, John P, Sijm, Dick T. H. M, Tolls, Johannes

“…Children can take up contaminated soil via hand-to-mouth behavior. The contaminants can be mobilized from the soil by digestive juices and thus become…”
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A practical approach to determine dose metrics for nanomaterials by Delmaar, Christiaan J.E., Peijnenburg, Willie J.G.M., Oomen, Agnes G., Chen, Jingwen, de Jong, Wim H., Sips, Adriënne J.A.M., Wang, Zhuang, Park, Margriet V.D.Z.

“…Traditionally, administered mass is used to describe doses of conventional chemical substances in toxicity studies. For deriving toxic doses of nanomaterials,…”
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Governance of advanced materials: Shaping a safe and sustainable future by Groenewold, Monique, Bleeker, Eric A.J., Noorlander, Cornelle W., Sips, Adriënne J.A.M., van der Zee, Margriet, Aitken, Robert J., Baker, James H., Bakker, Martine I., Bouman, Evert A., Doak, Shareen H., Drobne, Damjana, Dumit, Verónica I., Florin, Marie-Valentine, Fransman, Wouter, Gonzalez, Mar M., Heunisch, Elisabeth, Isigonis, Panagiotis, Jeliazkova, Nina, Jensen, Keld Alstrup, Kuhlbusch, Thomas, Lynch, Iseult, Morrison, Mark, Porcari, Andrea, Rodríguez-Llopis, Isabel, Pozuelo, Blanca M., Resch, Susanne, Säämänen, Arto J., Serchi, Tommaso, Soeteman-Hernandez, Lya G., Willighagen, Egon, Dusinska, Maria, Scott-Fordsmand, Janeck J.

“…The past few decades of managing the uncertain risks associated with nanomaterials have provided valuable insights (knowledge gaps, tools, methods, etc.) that…”
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Biokinetics of Nanomaterials: the Role of Biopersistence by Laux, Peter, Riebeling, Christian, Booth, Andy M, Brain, Joseph D, Brunner, Josephine, Cerrillo, Cristina, Creutzenberg, Otto, Estrela-Lopis, Irina, Gebel, Thomas, Johanson, Gunnar, Jungnickel, Harald, Kock, Heiko, Tentschert, Jutta, Tlili, Ahmed, Schäffer, Andreas, Sips, Adriënne J A M, Yokel, Robert A, Luch, Andreas

“…Nanotechnology risk management strategies and environmental regulations continue to rely on hazard and exposure assessment protocols developed for bulk…”
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Effects of probiotic bacteria on the bioaccessibility of aflatoxin B1 and ochratoxin A using an in vitro digestion model under fed conditions by Kabak, Bulent, Brandon, Esther F.A, Var, Isil, Blokland, Marco, Sips, Adrienne J.A.M

“…In the present study, we aimed at determining the release of aflatoxin B 1 (AFB 1 ) and ochratoxin A (OTA) from different food products in the…”
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Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food by Versantvoort, Carolien H.M., Oomen, Agnes G., Van de Kamp, Erwin, Rompelberg, Cathy J.M., Sips, Adriënne J.A.M.

“…Food is considered a major route of exposure to many contaminants. Only the fraction of the contaminant that is released from the food (bioaccessibility) and…”
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What do we (need to) know about the kinetic properties of nanoparticles in the body? by Hagens, Werner I., Oomen, Agnes G., de Jong, Wim H., Cassee, Flemming R., Sips, Adriënne J.A.M.

“…Nowadays the development and applications of nanotechnology are of major importance in both industrial and consumer areas. However, the knowledge on human…”
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Modernizing innovation governance to meet policy ambitions through trusted environments by Soeteman-Hernández, Lya G., Sutcliffe, Hilary R., Sluijters, Teun, van Geuns, Jonathan, Noorlander, Cornelle W., Sips, Adriënne J.A.M.

“…A vision for modernization of nanotechnology innovation governance is a Safe Innovation Approach (SIA). SIA combines two concepts: Safe-by-Design (SbD) and…”
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Nano-silver - a review of available data and knowledge gaps in human and environmental risk assessment by Wijnhoven, Susan W.P., Peijnenburg, Willie J.G.M., Herberts, Carla A., Hagens, Werner I., Oomen, Agnes G., Heugens, Evelyn H.W., Roszek, Boris, Bisschops, Julia, Gosens, Ilse, Van De Meent, Dik, Dekkers, Susan, De Jong, Wim H., van Zijverden, Maaike, Sips, Adriënne J.A.M., Geertsma, Robert E.

“…Nano-silver is used in an increasing number of products. Some of the applications have resulted in the concern of governments and the public, since little is…”
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Effects of probiotic bacteria on the bioaccessibility of aflatoxin B 1 and ochratoxin A using an in vitro digestion model under fed conditions by Kabak, Bulent, Brandon, Esther F. A., Var, Isil, Blokland, Marco, Sips, Adrienne J. A. M.

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