Search Results - "Siouve, Elise"

A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways by Morton, Stephen W, Lee, Michael J, Deng, Zhou J, Dreaden, Erik C, Siouve, Elise, Shopsowitz, Kevin E, Shah, Nisarg J, Yaffe, Michael B, Hammond, Paula T

“…Exposure to the EGFR (epidermal growth factor receptor) inhibitor erlotinib promotes the dynamic rewiring of apoptotic pathways, which sensitizes cells within…”
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Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors by Rousset, François, Cui, Lun, Siouve, Elise, Becavin, Christophe, Depardieu, Florence, Bikard, David

“…High-throughput genetic screens are powerful methods to identify genes linked to a given phenotype. The catalytic null mutant of the Cas9 RNA-guided nuclease…”
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Mechanistic insights into the rational design of masked antibodies by Orozco, Carolina T., Bersellini, Manuela, Irving, Lorraine M., Howard, Wesley W., Hargreaves, David, Devine, Paul W. A., Siouve, Elise, Browne, Gareth J., Bond, Nicholas J., Phillips, Jonathan J., Ravn, Peter, Jackson, Sophie E.

“…Although monoclonal antibodies have greatly improved cancer therapy, they can trigger side effects due to on-target, off-tumor toxicity. Over the past decade,…”
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Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination by Dunsmore, Lavinia, Navo, Claudio D., Becher, Julie, de Montes, Enrique Gil, Guerreiro, Ana, Hoyt, Emily, Brown, Libby, Zelenay, Viviane, Mikutis, Sigitas, Cooper, Jonathan, Barbieri, Isaia, Lawrinowitz, Stefanie, Siouve, Elise, Martin, Esther, Ruivo, Pedro R., Rodrigues, Tiago, da Cruz, Filipa P., Werz, Oliver, Vassiliou, George, Ravn, Peter, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.

“…Natural products that contain ortho -quinones show great potential as anticancer agents but have been largely discarded from clinical development because their…”
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Mechanistic insights into the rational design of masked antibodies by Orozco, Carolina T., Bersellini, Manuela, Irving, Lorraine M., Howard, Wesley W., Hargreaves, David, Devine, Paul W. A., Siouve, Elise, Browne, Gareth J., Bond, Nicholas J., Phillips, Jonathan J., Ravn, Peter, Jackson, Sophie E.

“…Although monoclonal antibodies have greatly improved cancer therapy, they can trigger side effects due to on-target, off-tumor toxicity. Over the past decade,…”
Get full text