Search Results - "Sio, Terence"

Strategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma by Oberoi, Rajneet K, Parrish, Karen E, Sio, Terence T, Mittapalli, Rajendar K, Elmquist, William F, Sarkaria, Jann N

“…Glioblastoma (GBM) is a lethal and aggressive brain tumor that is resistant to conventional radiation and cytotoxic chemotherapies. Molecularly targeted agents…”
Get full text

Intensity Modulated Proton Therapy Versus Intensity Modulated Photon Radiation Therapy for Oropharyngeal Cancer: First Comparative Results of Patient-Reported Outcomes by Sio, Terence T., MD, MS, Lin, Huei-Kai, MS, Shi, Qiuling, PhD, Gunn, G. Brandon, MD, Cleeland, Charles S., PhD, Lee, J. Jack, PhD, Hernandez, Mike, MS, Blanchard, Pierre, MD, PhD, Thaker, Nikhil G., MD, Phan, Jack, MD, PhD, Rosenthal, David I., MD, Garden, Adam S., MD, Morrison, William H., MD, Fuller, C. David, MD, PhD, Mendoza, Tito R., PhD, Mohan, Radhe, PhD, Wang, Xin Shelley, MD, MPH, Frank, Steven J., MD

“…Purpose We hypothesized that patients with oropharyngeal cancer treated with intensity modulated proton therapy (IMPT) would have lower symptom burdens, as…”
Get full text

The protective effects of quercetin nano-emulsion on intestinal mucositis induced by 5-fluorouracil in mice by Lotfi, Mandana, Kazemi, Sohrab, Shirafkan, Fatemeh, Hosseinzadeh, Rezvan, Ebrahimpour, Anahita, Barary, Mohammad, Sio, Terence T., Hosseini, Seyed Mohammad, Moghadamnia, Ali Akbar

“…Intestinal mucositis is one of chemotherapeutics' most common adverse effects, such as 5-fluorouracil (5-FU). Quercetin (QRC), a naturally occurring flavonoid,…”
Get full text

Stereotactic body radiotherapy (SBRT) for central and ultracentral node-negative lung tumors by Owen, Dawn, Sio, Terence T.

“…Advancements in imaging and radiotherapy (RT) techniques have allowed for remarkably precise delivery of high radiation dose per treatment fraction to…”
Get full text

Reirradiation of Head and Neck Cancers With Proton Therapy: Outcomes and Analyses by Phan, Jack, MD, PhD, Sio, Terence T., MD, MS, Nguyen, Theresa P., BS, Takiar, Vinita, MD, PhD, Gunn, G. Brandon, MD, Garden, Adam S., MD, Rosenthal, David I., MD, Fuller, Clifton D., MD, PhD, Morrison, William H., MD, Beadle, Beth, MD, PhD, Ma, Dominic, BS, Zafereo, Mark E., MD, Hutcheson, Kate A., PhD, Kupferman, Michael E., MD, William, William N., MD, Frank, Steven J., MD

“…Purpose Reirradiation of head and neck (H&N) cancer is a clinical challenge. Proton radiation therapy (PRT) offers dosimetric advantages for normal tissue…”
Get full text

Evaluating large language models on a highly-specialized topic, radiation oncology physics by Holmes, Jason, Liu, Zhengliang, Zhang, Lian, Ding, Yuzhen, Sio, Terence T, McGee, Lisa A, Ashman, Jonathan B, Li, Xiang, Liu, Tianming, Shen, Jiajian, Liu, Wei

“…We present the first study to investigate Large Language Models (LLMs) in answering radiation oncology physics questions. Because popular exams like AP…”
Get full text

The effect of propolis on 5-fluorouracil-induced cardiac toxicity in rats by Barary, Mohammad, Hosseinzadeh, Rezvan, Kazemi, Sohrab, Liang, Jackson J., Mansoori, Razieh, Sio, Terence T., Hosseini, Mohammad, Moghadamnia, Ali Akbar

“…5-Fluorouracil (5-FU) is one of the most common chemotherapeutic agents used in treating solid tumors, and the 5-FU-induced cardiotoxicity is the second cause…”
Get full text

Intensity‐modulated proton therapy (IMPT) interplay effect evaluation of asymmetric breathing with simultaneous uncertainty considerations in patients with non‐small cell lung cancer by Shan, Jie, Yang, Yunze, Schild, Steven E., Daniels, Thomas B., Wong, William W., Fatyga, Mirek, Bues, Martin, Sio, Terence T., Liu, Wei

“…Purpose Intensity‐modulated proton therapy (IMPT) is sensitive to uncertainties from patient setup and proton beam range, as well as interplay effect. In…”
Get full text

A novel and individualized robust optimization method using normalized dose interval volume constraints (NDIVC) for intensity‐modulated proton radiotherapy by Shan, Jie, Sio, Terence T., Liu, Chenbin, Schild, Steven E., Bues, Martin, Liu, Wei

“…Purpose Intensity‐modulated proton therapy (IMPT) is known to be sensitive to patient setup and range uncertainty issues. Multiple robust optimization methods…”
Get full text

The Impact of Tumor Treating Fields on Glioblastoma Progression Patterns by Glas, Martin, Ballo, Matthew T., Bomzon, Ze'ev, Urman, Noa, Levi, Shay, Lavy-Shahaf, Gitit, Jeyapalan, Suriya, Sio, Terence T., DeRose, Paul M., Misch, Martin, Taillibert, Sophie, Ram, Zvi, Hottinger, Andreas F., Easaw, Jacob, Kim, Chae-Yong, Mohan, Suyash, Stupp, Roger

“…Tumor-treating fields (TTFields) are an antimitotic treatment modality that interfere with glioblastoma (GBM) cell division and organelle assembly by…”
Get full text

Radiation therapy considerations during the COVID‐19 Pandemic: Literature review and expert opinions by Mohindra, Pranshu, Buckey, Courtney R., Chen, Shifeng, Sio, Terence T., Rong, Yi

“…1 More than 662,000 cases have been reported in the United States with more than 29,000 deaths. 2 The overall crude mortality rate now stands at 6.6% (may…”
Get full text

Deep-learning based fast and accurate 3D CT deformable image registration in lung cancer by Ding, Yuzhen, Feng, Hongying, Yang, Yunze, Holmes, Jason, Liu, Zhengliang, Liu, David, Wong, William W, Yu, Nathan Y, Sio, Terence T, Schild, Steven E, Li, Baoxin, Liu, Wei

“…Deformable Image Registration (DIR) is an essential technique required in many applications of radiation oncology. However, conventional DIR approaches…”
Get full text

Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial by Sio, Terence T, Le-Rademacher, Jennifer G, Leenstra, James L, Loprinzi, Charles L, Rine, Grant, Curtis, Amarinthia, Singh, Anurag K, Martenson, James A, Novotny, Paul J, Tan, Angelina D, Qin, Rui, Ko, Stephen J, Reiter, Paul L, Miller, Robert C

“…IMPORTANCE: Oral mucositis causes substantial morbidity during head and neck radiotherapy. In a randomized study, doxepin mouthwash was shown to reduce oral…”
Get full text

Impact of Spot Size and Spacing on the Quality of Robustly Optimized Intensity Modulated Proton Therapy Plans for Lung Cancer by Liu, Chenbin, Schild, Steven E., Chang, Joe Y., Liao, Zhongxing, Korte, Shawn, Shen, Jiajian, Ding, Xiaoning, Hu, Yanle, Kang, Yixiu, Keole, Sameer R., Sio, Terence T., Wong, William W., Sahoo, Narayan, Bues, Martin, Liu, Wei

“…To investigate how spot size and spacing affect plan quality, robustness, and interplay effects of robustly optimized intensity modulated proton therapy (IMPT)…”
Get full text

NRG Oncology and Particle Therapy Co-Operative Group Patterns of Practice Survey and Consensus Recommendations on Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy and Hypofractionated Radiation Therapy for Thoracic Malignancies by Liu, Wei, Feng, Hongying, Taylor, Paige A., Kang, Minglei, Shen, Jiajian, Saini, Jatinder, Zhou, Jun, Giap, Huan B., Yu, Nathan Y., Sio, Terence S., Mohindra, Pranshu, Chang, Joe Y., Bradley, Jeffrey D., Xiao, Ying, Simone, Charles B., Lin, Liyong

“…Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic…”
Get full text

NRG Oncology and PTCOG Patterns of Practice Survey and Consensus Recommendations on Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy and Hypofractionated Radiation Therapy for Thoracic Malignancies by Liu, Wei, Feng, Hongying, Taylor, Paige A, Kang, Minglei, Shen, Jiajian, Saini, Jatinder, Zhou, Jun, Giap, Huan B, Yu, Nathan Y, Sio, Terence S, Mohindra, Pranshu, Chang, Joe Y, Bradley, Jeffrey D, Xiao, Ying, Simone, 2nd, Charles B, Lin, Liyong

“…Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic…”
Get full text

Technical Note: 4D robust optimization in small spot intensity‐modulated proton therapy (IMPT) for distal esophageal carcinoma by Feng, Hongying, Shan, Jie, Ashman, Jonathan B., Rule, William G., Bhangoo, Ronik S., Yu, Nathan Y., Chiang, Jennifer, Fatyga, Mirek, Wong, William W., Schild, Steven E., Sio, Terence T., Liu, Wei

“…Purpose To compare the dosimetric performances of small‐spot three‐dimensional (3D) and four‐dimensional (4D) robustly optimized intensity‐modulated proton…”
Get full text

Coronavirus disease 2019 (Covid‐19) vaccination recommendations in special populations and patients with existing comorbidities by Mohseni Afshar, Zeinab, Babazadeh, Arefeh, Janbakhsh, Alireza, Mansouri, Feizollah, Sio, Terence T., Sullman, Mark J. M., Carson‐Chahhoud, Kristin, Hosseinzadeh, Rezvan, Barary, Mohammad, Ebrahimpour, Soheil

“…Summary Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a crucial step in ending the current worldwide pandemic. However,…”
Get full text

Beam mask and sliding window‐facilitated deep learning‐based accurate and efficient dose prediction for pencil beam scanning proton therapy by Zhang, Lian, Holmes, Jason M., Liu, Zhengliang, Vora, Sujay A., Sio, Terence T., Vargas, Carlos E., Yu, Nathan Y., Keole, Sameer R., Schild, Steven E., Bues, Martin, Li, Sheng, Liu, Tianming, Shen, Jiajian, Wong, William W., Liu, Wei

“…Background Accurate and efficient dose calculation is essential for on‐line adaptive planning in proton therapy. Deep learning (DL) has shown promising dose…”
Get full text

Technical Note: Treatment planning system (TPS) approximations matter — comparing intensity‐modulated proton therapy (IMPT) plan quality and robustness between a commercial and an in‐house developed TPS for nonsmall cell lung cancer (NSCLC) by Liu, Chenbin, Yu, Nathan Y., Shan, Jie, Bhangoo, Ronik S., Daniels, Thomas B., Chiang, Jennifer S., Ding, Xiaoning, Lara, Pedro, Patrick, Christopher L., Archuleta, James P., DeWees, Todd, Hu, Yanle, Schild, Steven E., Bues, Martin, Sio, Terence T., Liu, Wei

“…Purpose Approximate dose calculation methods were used in the nominal dose distribution and the perturbed dose distributions due to uncertainties in a…”
Get full text