Search Results - "Sinnott, Deborah"

Syntheses and Characterization of the Acyl Glucuronide and Hydroxy Metabolites of Diclofenac by Kenny, Jane R, Maggs, James L, Meng, Xiaoli, Sinnott, Deborah, Clarke, Stephen E, Park, B. Kevin, Stachulski, Andrew V

“…In humans, metabolism of the commonly used nonsteroidal antiinflammatory drug diclofenac 1 yields principally the 4‘-hydroxy 2, 5-hydroxy 3, and acyl…”
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Convenient syntheses of deoxypyranose sugars from glucuronolactone by Stanford (nee Sinnott), Deborah, Stachulski, Andrew V.

“…d-Glucuronolactone is a versatile starting material for the synthesis of a number of deoxy sugars, as shown. The key steps are base-catalysed elimination from…”
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Glucuronidation of steroidal alcohols using iodosugar and imidate donors by Harding, John R, King, Clare D, Perrie, Jennifer A, Sinnott, Deborah, Stachulski, Andrew V

“…We report a study of the glucuronidation of a number of important steroidal secondary alcohols. The alcohols studied are androsterone 7, epiandrosterone 8,…”
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Glycosidation with a Disarmed Glycosyl Iodide:  Promotion and Scope by Perrie, Jennifer A, Harding, John R, King, Clare, Sinnott, Deborah, Stachulski, Andrew V

“…Glucuronyl iodide 1 has been studied in detail as a “disarmed” glycosyl donor. In a model reaction, using N-iodosuccinimide (NIS) as a promoter and…”
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