Search Results - "Sinniah, Raja"

Inherited Interleukin-12 Deficiency: IL12B Genotype and Clinical Phenotype of 13 Patients from Six Kindreds by Picard, Capucine, Fieschi, Claire, Altare, Frédéric, Al-Jumaah, Suliman, Al-Hajjar, Sami, Feinberg, Jacqueline, Dupuis, Stéphanie, Soudais, Claire, Al-Mohsen, Ibrahim Zaid, Génin, Emmanuelle, Lammas, David, Kumararatne, Dinakantha S., Leclerc, Tony, Rafii, Arash, Frayha, Husn, Murugasu, Belinda, Wah, Lee Bee, Sinniah, Raja, Loubser, Michael, Okamoto, Emi, Al-Ghonaium, Abdulaziz, Tufenkeji, Haysam, Abel, Laurent, Casanova, Jean-Laurent

“…Interleukin-12 (IL12) is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-γ production by natural-killer and…”
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Neuropathological Homology in True Galloway-Mowat Syndrome by Keith, Julia, Fabian, Victoria A., Walsh, Peter, Sinniah, Raja, Robitaille, Yves

“…Galloway-Mowat syndrome is a rare condition that is likely hereditary though the underlying offending gene has not been identified, and is characterized by…”
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Effects of angiotensin II on regional afferent and efferent arteriole dimensions and the glomerular pole by Denton, K M, Anderson, W P, Sinniah, R

“…The diversity of renal arteriole diameters in different cortical regions has important consequences for control of glomerular capillary pressure. We examined…”
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Role of differential and cell type-specific expression of cell cycle regulatory proteins in mediating progressive glomerular injury in human IgA nephropathy by Qiu, Lian-Qun, Sinniah, Raja, Hsu, Stephen I-H

“…The activities of cell cycle regulatory proteins have been reported to be associated with the development of pathological lesions in glomerulonephritis. To…”
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Acute renal failure from myoglobinuria secondary to myositis from severe falciparum malaria by Sinniah, R, Lye, W

“…Renal disease is a common complication in malaria infection. In acute falciparum malaria renal involvement is usually mild, but in severe disease acute renal…”
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A case of end stage sarcoidosis in an explanted heart by Foo, Tiffany, Dias, Peter, Sinniah, Raja

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Urine laminin and kallikrein, markers of tubulointerstitial damage in experimental protein overload on pre-existing renal damage by Saw, Sharon, Aw, Tar-Choon, Sinniah, Raja

“…We studied the response of urinary protein overload on pre-existing tubulointerstitial nephritis (TIN), which was induced in male Sprague Dawley rats by…”
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Pathogenic Role of NF-κB Activation in Tubulointerstitial Inflammatory Lesions in Human Lupus Nephritis by Zheng, Ling, Sinniah, Raja, Hsu, Stephen I-Hong

“…In vitro and in vivo experimental studies suggest that the transcription factor NF-κB plays a role in tubulointerstitial injury. We investigated possible…”
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Renal Tubular Basement Membrane Changes in Tubulointerstitial Damage in Patients with Glomerular Diseases by Raja Sinniah, Tahir N. Khan

“…Injury to renal tubules and interstitium occur in various glomerular diseases, leading to functional impairment. Tubular basement membrane (TBM) is an…”
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Dasatinib therapy for systemic mastocytosis: four cases by Purtill, Duncan, Cooney, Julian, Sinniah, Raja, Carnley, Ben, Cull, Gavin, Augustson, Bradley, Cannell, Paul

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Study of renal tubular glycoconjugates in tubulointerstitial damage using conjugated lectins by Khan, T N, Sinniah, R

“…Changes in the glycoconjugates of renal tubules associated with tubular damage were studied by lectin histochemistry, and their possible significance was…”
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Renal tubular antiproteinase (alpha-1-antitrypsin and alpha-1-antichymotrypsin) response in tubulo-interstitial damage by Khan, T N, Sinniah, R

“…We studied the role of proteinase inhibitors (Pls) alpha 1-antitrypsin and alpha 1-antichymotrypsin in relation to lysozyme (LZM), and membrane attack complex…”
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Morphometric study showing the importance of distal tubular damage in impaired creatinine clearance by Khan, T N, Sinniah, R

“…It is established that the glomerular filtration rate (GFR) is affected by tubulointerstitial lesions (TIL) in various glomerulonephritides. The fall in GFR is…”
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In situ glomerular expression of activated NF-κB in human lupus nephritis and other non-proliferative proteinuric glomerulopathy by LING ZHENG, SINNIAH, Raja, HSU, Stephen I-Hong

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Renal cell apoptosis and proliferation may be linked to nuclear factor– κB activation and expression of inducible nitric oxide synthase in patients with lupus nephritis by Zheng, Ling, Sinniah, Raja, Hsu, Stephen I-Hong

“…The mechanism of renal cell apoptosis involves transcriptional activation of the inducible nitric oxide synthase ( iNOS) gene by nuclear factor (NF)- κB. The…”
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Pathogenic role of NF-kappaB activation in tubulointerstitial inflammatory lesions in human lupus nephritis by Zheng, Ling, Sinniah, Raja, Hsu, Stephen I-Hong

“…In vitro and in vivo experimental studies suggest that the transcription factor NF-kappaB plays a role in tubulointerstitial injury. We investigated possible…”
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Animal model of margosa oil ingestion with Reye-like syndrome. Pathogenesis of microvesicular fatty liver by Sinniah, R, Sinniah, D, Chia, L S, Baskaran, G

“…The aetiology and pathogenesis of Reye's syndrome (RS) are incompletely understood. A number of environmental toxins and biological agents, including viruses,…”
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Cellular and humoral immune responses in Campylobacter pylori-associated chronic gastritis by Kazi, J I, Sinniah, R, Jaffrey, N A, Alam, S M, Zaman, V, Zuberi, S J, Kazi, A M

“…Gastric cellular and humoral immune response investigated by immunoperoxidase staining of 53 antral biopsies showed significant differences in Campylobacter…”
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Downregulation of Bcl-2 by podocytes is associated with progressive glomerular injury and clinical indices of poor renal prognosis in human IgA nephropathy by OIU, Lian-Oun, SINNIAH, Raja, HSU, Stephen I-Hong

“…Bcl-2 defines a new class of proto-oncogenes that block cell death without promoting cell proliferation. To elucidate the role of Bcl-2 in the development of…”
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Coupled induction of iNOS and p53 upregulation in renal resident cells may be linked with apoptotic activity in the pathogenesis of progressive IgA nephropathy by Qiu, Lian-Qun, Sinniah, Raja, Hsu, Stephen I-Hong

“…In situ hybridization, immunohistochemistry, and TUNEL staining were applied to renal biopsy specimens of immunoglobulin A nephropathy (IgAN) patients to…”
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