Search Results - "Sinnecker, D."

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy by Moretti, A., Fonteyne, L., Giesert, F., Hoppmann, P., Meier, A. B., Bozoglu, T., Baehr, A., Schneider, C. M., Sinnecker, D., Klett, K., Fröhlich, T., Rahman, F. Abdel, Haufe, T., Sun, S., Jurisch, V., Kessler, B., Hinkel, R., Dirschinger, R., Martens, E., Jilek, C., Graf, A., Krebs, S., Santamaria, G., Kurome, M., Zakhartchenko, V., Campbell, B., Voelse, K., Wolf, A., Ziegler, T., Reichert, S., Lee, S., Flenkenthaler, F., Dorn, T., Jeremias, I., Blum, H., Dendorfer, A., Schnieke, A., Krause, S., Walter, M. C., Klymiuk, N., Laugwitz, K. L., Wolf, E., Wurst, W., Kupatt, C.

“…Frameshift mutations in the DMD gene, encoding dystrophin, cause Duchenne muscular dystrophy (DMD), leading to terminal muscle and heart failure in patients…”
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Influence of radiotherapy on cardiac implantable device lead parameters by Warmbrunn, J, Straube, C, Haase, H U, Sinnecker, D, Laugwitz, K L, Combs, S E, Schneider, S, Habermehl, D

“…Abstract Purpose Incidences of both cardiac implantable electronic devices (CIED) and malignant tumors are rising, likewise the number of patients undergoing…”
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P4844Sleep-disordered breathing assessed from cyclic variation of heart rate in Holter ECGs as a risk predictor after myocardial infarction by Sinnecker, D, Cao, X, Muller, A, Barthel, P, Schmidt, G

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Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome by Krane, Markus, Dreßen, Martina, Santamaria, Gianluca, My, Ilaria, Schneider, Christine M., Dorn, Tatjana, Laue, Svenja, Mastantuono, Elisa, Berutti, Riccardo, Rawat, Hilansi, Gilsbach, Ralf, Schneider, Pedro, Lahm, Harald, Schwarz, Sascha, Doppler, Stefanie A., Paige, Sharon, Puluca, Nazan, Doll, Sophia, Neb, Irina, Brade, Thomas, Zhang, Zhong, Abou-Ajram, Claudia, Northoff, Bernd, Holdt, Lesca M., Sudhop, Stefanie, Sahara, Makoto, Goedel, Alexander, Dendorfer, Andreas, Tjong, Fleur V.Y., Rijlaarsdam, Maria E., Cleuziou, Julie, Lang, Nora, Kupatt, Christian, Bezzina, Connie, Lange, Rüdiger, Bowles, Neil E., Mann, Matthias, Gelb, Bruce D., Crotti, Lia, Hein, Lutz, Meitinger, Thomas, Wu, Sean, Sinnecker, Daniel, Gruber, Peter J., Laugwitz, Karl-Ludwig, Moretti, Alessandra

“…Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most common and severe…”
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PO-0869: Influence of cardiac implantable electronic devices onto dosimetric parameters during radiotherapy by Straube, C., Warmbrunn, J., Haase, H.U., Sinnecker, D., Laugwitz, K.L., Combs, S.E., Schneider, S., Habermehl, D.

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P2561All-optical imaging of membrane potential and calcium signalling in patient-specific hiPSC-derived cardiomyocytes by Sinnecker, D., Chen, Z., Goedel, A., My, I., Dreizehnter, L., Moretti, A., Laugwitz, K.-L.

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Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors by Poch, Christine M., Foo, Kylie S., De Angelis, Maria Teresa, Jennbacken, Karin, Santamaria, Gianluca, Bähr, Andrea, Wang, Qing-Dong, Reiter, Franziska, Hornaschewitz, Nadja, Zawada, Dorota, Bozoglu, Tarik, My, Ilaria, Meier, Anna, Dorn, Tatjana, Hege, Simon, Lehtinen, Miia L., Tsoi, Yat Long, Hovdal, Daniel, Hyllner, Johan, Schwarz, Sascha, Sudhop, Stefanie, Jurisch, Victoria, Sini, Marcella, Fellows, Mick D., Cummings, Matthew, Clarke, Jonathan, Baptista, Ricardo, Eroglu, Elif, Wolf, Eckhard, Klymiuk, Nikolai, Lu, Kun, Tomasi, Roland, Dendorfer, Andreas, Gaspari, Marco, Parrotta, Elvira, Cuda, Giovanni, Krane, Markus, Sinnecker, Daniel, Hoppmann, Petra, Kupatt, Christian, Fritsche-Danielson, Regina, Moretti, Alessandra, Chien, Kenneth R., Laugwitz, Karl-Ludwig

“…Heart regeneration is an unmet clinical need, hampered by limited renewal of adult cardiomyocytes and fibrotic scarring. Pluripotent stem cell-based strategies…”
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Pluripotent stem cell models of human heart disease by Moretti, Alessandra, Laugwitz, Karl-Ludwig, Dorn, Tatjana, Sinnecker, Daniel, Mummery, Christine

“…Understanding the molecular basis of many cardiac diseases has been hampered by the lack of appropriate in vitro cell culture models that accurately reflect…”
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211Machine learning in risk prediction of post-MI patients by Steger, A, Hapfelmeier, A, Sinnecker, D, Dommasch, M, Mueller, A, Barthel, P, Schmidt, G

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P1622Assessment of expiration-triggered sinus arrhythmia from high-resolution ECG recordings for risk prediction in patients after acute myocardial infarction by Dommasch, M., Sinnecker, D., Steger, A., Barthel, P., Mueller, A., Ubrich, R., Laugwitz, KL, Schmidt, G.

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P1612Bivariate PRSA: a novel tool for detection of functional respiration-triggered SA-blocks by Steger, A., Mueller, A., Toifl, M., Sinnecker, D., Dommasch, M., Barthel, P., Pramstaller, PP, Schmidt, G.

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Negating the dominant-negative allele: a new treatment paradigm for arrhythmias explored in human induced pluripotent stem cell-derived cardiomyocytes by Sinnecker, Daniel, Moretti, Alessandra, Laugwitz, Karl-Ludwig

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Reversible Photobleaching of Enhanced Green Fluorescent Proteins by Sinnecker, Daniel, Voigt, Philipp, Hellwig, Nicole, Schaefer, Michael

“…Color variants of green fluorescent protein (GFP) are increasingly used for multicolor imaging, fluorescence resonance energy transfer (FRET), and fluorescence…”
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Rationale and design of the EU‐CERT‐ICD prospective study: comparative effectiveness of prophylactic ICD implantation by Zabel, Markus, Sticherling, Christian, Willems, Rik, Lubinski, Andrzej, Bauer, Axel, Bergau, Leonard, Braunschweig, Frieder, Brugada, Josep, Brusich, Sandro, Conen, David, Cygankiewicz, Iwona, Flevari, Panagiota, Taborsky, Milos, Hansen, Jim, Hasenfuß, Gerd, Hatala, Robert, Huikuri, Heikki V., Iovev, Svetoslav, Kääb, Stefan, Kaliska, Gabriela, Kasprzak, Jaroslaw D., Lüthje, Lars, Malik, Marek, Novotny, Tomas, Pavlović, Nikola, Schmidt, Georg, Shalganov, Tchavdar, Sritharan, Rajeeva, Schlögl, Simon, Szavits Nossan, Janko, Traykov, Vassil, Tuinenburg, Anton E., Velchev, Vasil, Vos, Marc A., Willich, Stefan N., Friede, Tim, Svendsen, Jesper Hastrup, Merkely, Béla

“…Aims The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. The EUropean Comparative…”
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Real-time analysis of phospholipase C activity during different patterns of receptor-induced Ca super(2+) responses in HEK293 cells by Sinnecker, D, Schaefer, M

“…[Ca super(2+)] sub(i) oscillations can either depend on oscillatory inositol-1, 4, 5-trisphosphate (InsP sub(3)) formation by phospholipase C (PLC) or rely on…”
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Real-time analysis of phospholipase C activity during different patterns of receptor-induced Ca2+ responses in HEK293 cells by Sinnecker, Daniel, Schaefer, Michael

“…[Ca(2+)](i) oscillations can either depend on oscillatory inositol-1,4,5-trisphosphate (InsP(3)) formation by phospholipase C (PLC) or rely on local feedback…”
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Expiration-Triggered Sinus Arrhythmia Predicts Outcome in Survivors of Acute Myocardial Infarction by Sinnecker, Daniel, MD, Dommasch, Michael, MD, Steger, Alexander, MD, Berkefeld, Anna, MD, Hoppmann, Petra, MD, Müller, Alexander, MSc, Gebhardt, Josef, MSc, Barthel, Petra, MD, Hnatkova, Katerina, PhD, Huster, Katharina M., MD, Laugwitz, Karl-Ludwig, MD, Malik, Marek, MD, PhD, Schmidt, Georg, MD

“…Abstract Background Respiratory sinus arrhythmia (RSA), a measure of cardiac vagal modulation, provides cardiac risk stratification information. RSA can be…”
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Nocturnal Respiratory Rate Predicts Non–Sudden Cardiac Death in Survivors of Acute Myocardial Infarction by Dommasch, Michael, MD, Sinnecker, Daniel, MD, Barthel, Petra, MD, Müller, Alexander, MSc, Dirschinger, Ralf J., MD, Hapfelmeier, Alexander, PhD, Huster, Katharina M., MD, Laugwitz, Karl-Ludwig, MD, Malik, Marek, MD, PhD, Schmidt, Georg, MD

“…To the Editor: Survivors of acute myocardial infarction (MI) are at substantial risk of subsequent death due to progressive heart failure, arrhythmic events,…”
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Assessment of mean respiratory rate from ECG recordings for risk stratification after myocardial infarction by Sinnecker, Daniel, MD, Dommasch, Michael, MD, Barthel, Petra, MD, Müller, Alexander, MSc, Dirschinger, Ralf J., MD, Hapfelmeier, Alexander, PhD, Huster, Katharina M., MD, Laugwitz, Karl-Ludwig, MD, Malik, Marek, PhD, MD, Schmidt, Georg, MD

“…Abstract Background We recently reported that nocturnal respiratory rate (NRR) predicts non-sudden cardiac death in survivors of myocardial infarction (MI)…”
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Sex differences in the non-invasive risk stratification and prognosis after myocardial infarction by Sinnecker, Daniel, MD, Huster, Katharina M., MD, Müller, Alexander, MSc, Dommasch, Michael, MD, Hapfelmeier, Alexander, PhD, Gebhardt, Josef, MSc, Hnatkova, Katerina, PhD, Laugwitz, Karl-Ludwig, MD, Malik, Marek, PhD, MD, Barthel, Petra, MD, Schmidt, Georg, MD

“…Abstract Background Women have unfavorable prognosis after myocardial infarction (MI). This text describes sex differences in mortality and in the power of…”
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