Search Results - "Sinkovics, Joseph G"

The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review) by Sinkovics, Joseph G

“…Int J Oncol 47: 1211–1229, 2015 After the publication of the article, the author noted that there was an error on page 1212, right column, paragraph entitled…”
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The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review) by SINKOVICS, JOSEPH G

“…The cell survival pathways of the diploblastic early multicellular eukaryotic hosts contain and operate the molecular machinery resembling those of malignantly…”
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Molecular biology of oncogenic inflammatory processes. I. Non-oncogenic and oncogenic pathogens, intrinsic inflammatory reactions without pathogens, and microRNA/DNA interactions (Review) by SINKOVICS, Joseph G

“…In some inflammasomes tumor cells are generated. The internal environment of the inflammasome is conducive to the induction of malignant transformation…”
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Self-defense of human sarcoma cells against cytolytic lymphoid cells of their host by Sinkovics, Joseph G, Horvath, Joseph C

“…Metastatic human sarcomas temporarily respond to radio-chemotherapy relapse and remain highly resistant to further combination chemotherapy as to a curative…”
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Natural and genetically engineered viral agents for oncolysis and gene therapy of human cancers by Sinkovics, Joseph G, Horvath, Joseph C

“…Based on personal acquaintances and experience dating back to the early 1950s, the senior author reviews the history of viral therapy of cancer. He points out…”
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Horizontal gene transfers and cell fusions in microbiology, immunology and oncology (Review) by SINKOVICS, Joseph G

“…Evolving young genomes of archaea, prokaryota and unicellular eukaryota were wide open for the acceptance of alien genomic sequences, which they often…”
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Comments on cultured human sarcoma cells by Sinkovics, Joseph G

“…Human sarcoma cell populations maintained in culture reflect to the native tumor cells better if the culture retains those nonmalignant cells that comprised…”
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Horizontal gene transfers with or without cell fusions in all categories of the living matter by Sinkovics, Joseph G

“…This article reviews the history of widespread exchanges of genetic segments initiated over 3 billion years ago, to be part of their life style, by…”
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The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes by Sinkovics, J G

“…Malignantly transformed (cancer) cells of multicellular hosts, including human cells, operate activated biochemical pathways that recognizably derived from…”
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Evidence accumulating in support of cancer vaccines combined with chemotherapy : A pragmatic review of past and present efforts by SINKOVICS, Joseph G, HORVATH, Joseph C

“…In the early 1970s supervised clinical trials were initiated at The University of Texas M.D. Anderson Hospital in Houston, TX, for the combination of viral…”
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Adult human sarcomas. I. Basic science by Sinkovics, Joseph G

“…When connective tissue undergoes malignant transformation, glioblastomas and sarcomas arise. However, the ancient biochemical mechanisms, which are now…”
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Human natural killer cells: a comprehensive review by Sinkovics, Joseph G, Horvath, Joseph C

“…The senior author of this comprehensive review observed and reported in 1969 that his lymphocytes killed allogeneic tumor cells in vitro. Some of his research…”
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Adult human sarcomas. II. Medical oncology by Sinkovics, Joseph G

“…Human sarcoma cells can be killed by radio- and chemotherapy, but tumor cells acquiring resistance frequently kill the patient. A keen understanding of the…”
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Antileukemia and antitumor effects of the graft-versus-host disease: a new immunovirological approach by Sinkovics, Joseph G

“…In leukemic mice, the native host's explicit and well-defined immune reactions to the leukemia virus (a strong exogenous antigen) and to leukemia cells…”
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Newcastle disease virus (NDV): brief history of its oncolytic strains by Sinkovics, Joseph G., Horvath, Joseph C.

“…Background: While genetically engineered viruses are now being tested for the virus therapy of human cancers, some naturally occurring viruses display…”
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Abstract 3078: The fer/FerT cell survival pathway of the ancestral sponge ( Sycon raphanus ) becomes a mitochondrial proto-oncogene in the human genome by Sinkovics, Joseph G.

“…The Fer/FerT (truncated) genes and their encoded 879 aa / 100 kDa proteins (fujinami poultry sarcoma; feline sarcoma-related kinases) were discovered in the…”
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The cnidarian origin of the proto-oncogenes NF-[kappa]B/STAT and WNT-like oncogenic pathway drives the ctenophores by Sinkovics, Joseph G

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Chondrosarcoma cell differentiation: Experimental data and possible molecular mechanisms by Sinkovics, Joseph G.

“…A mixed population of lymphocytes from a healthy donor co-existed with an established culture of allogeneic chondrosarcoma cells, during which time the tumor…”
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[Erratum] Virological and immunological connotations of apoptotic and anti-apoptotic forces in neoplasia by Sinkovics, Joseph, Horvath, Joseph

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Studies on influenza- and Newcastle disease virus at the University's Institute of Microbiology (Budapest) in 1948-50 by Sinkovics, J G

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