Search Results - "Sinkovics, J G"

Vaccination against human cancers (review) by Sinkovics, J G, Horvath, J C

“…Classical and molecular immunological means of active tumor-specific immunization against human cancers yielded whole cell or tumor cell lysate vaccines of…”
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Newcastle disease virus (NDV): brief history of its oncolytic strains by Sinkovics, Joseph G., Horvath, Joseph C.

“…Background: While genetically engineered viruses are now being tested for the virus therapy of human cancers, some naturally occurring viruses display…”
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Genes of ancient microtubule-stabilizing proteins traveled through pre-Cambrian Echinoidea to advanced life forms of dry land and ended up in the human genome as the fusion oncogenes-oncoproteins eml1/EML1-abl/ABL, and eml4/EML4-alk/ALK by J G Sinkovics

“…The genes eml1/4 of the Echinodermata microtubule-stabilizing gene product-like 1/4 proteins EML1/4 of the sea cucumbers (Holothuroidea) traveled through the…”
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The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes by Sinkovics, J G

“…Malignantly transformed (cancer) cells of multicellular hosts, including human cells, operate activated biochemical pathways that recognizably derived from…”
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Virus therapy of human cancers by Sinkovics, J G, Horvath, J C

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Virological and immunological connotations of apoptotic and anti-apoptotic forces in neoplasia by Sinkovics, J G, Horvath, J C

“…Against the background of its earliest recognition, programmed cell death (PCD) or apoptosis (A) is presented in its fundamental biological contexts…”
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Kaposi's sarcoma: breeding ground of herpesviridae - A tour de force over viral evolution (review) by Sinkovics, J G, Horvath, J C

“…After reviewing the molecular biological basis of prominent theories for the integration of viruses into the earliest forms of living matter, an account is…”
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Can virus therapy of human cancer be improved by apoptosis induction? by Sinkovics, J.G., Horvath, J.

“…Direct virus inoculations and viral oncolysates may induce temporary remissions and prolong life with reduced tumor burden, or decrease relapse rates but fall…”
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Role of Apoptosis in Health and Disease by Sinkovics, Joseph G, Horvath, Joseph C

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A notable phenomenon recapitulated. A fusion product of a murine lymphoma cell and a leukemia virus-neutralizing antibody-producer host plasma cell formed spontaneously and secreting the specific antibody continuously by Sinkovics, J G

“…In the mid-1960s the #620 cell passage line of a murine lymphoma-leukemia was developed at the Section of Clinical Tumor Virology and Immunology, Department of…”
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Oncogenes and growth factors by Sinkovics, J G

“…Certain polypeptide gene products regulate mitosis, differentiation, and other basic biologic functions of cells. These genes and their products are well…”
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Hodgkin's disease revisited: Reed-Sternberg cells as natural hybridomas by Sinkovics, J G

“…The formation of natural hybridomas during the course of malignant lymphoproliferative diseases was first observed in 1969, and many times thereafter. This…”
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Active tumor-specific immunization of the bone marrow (progenitor stem cell) donor by Sinkovics, J G

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Kaposi's sarcoma: its 'oncogenes' and growth factors by Sinkovics, J G

“…Viral genes capable of inducing vascular tumors in the skin of transgenic mice are the tat gene of HIV-1 and polyoma virus' middle T antigen gene. Instead of…”
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Human chorionic gonadotropin‐beta subunit gene expression in cultured human fetal and cancer cells of different types and origins by Sinkovics, Joseph G.

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The molecular biology and immunology of glioblastoma multiforme (GBM) with the presentation of an immunotherapy protocol for a clinical trial by Sinkovics, J G, Horvath, J C

“…After a short explanatory Introduction, an immunotherapy protocol is presented for glioblastoma multiforme (GBM). GBM is considered to be an incurable tumor;…”
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Adoptive immunotherapy with activated peripheral blood lymphocytes by Horvath, J, Sinkovics, J G

“…Adoptive immunotherapy is used to treat malignant tumors resistant to conventional therapeutic modalities. Patients with metastatic melanoma, renal cell…”
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Oncogenes-antioncogenes and virus therapy of cancer by Sinkovics, J G

“…Viruses can render services to mankind. 1. Retroviruses pinpoint and transduce cellular oncogenes. 2. Retroviral vectors can introduce antioncogenes (the RB…”
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Cytotoxic lymphocytes by Sinkovics, J G

“…Interactions between human lymphocytes and target cells are highly variable. Lymphocytes may enter fibroblasts, establish cytoplasmic bridges, and draw…”
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Autologous activated lymphocyte therapy in a community hospital by Horváth, J, Szabó-Szabari, M, Sinkovics, J G

“…In the authors' institution patients suffering from metastatic melanoma, renal cell carcinoma or mesothelioma, resistant to conventional therapeutic…”
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